Why not just use a totem-pole pre-driver for the MOSFET ?

BTW, this touches on a challenge when designing HV drivers, whether they 
are for DC-DC converters or driving cathodes. Most high-voltage NMOS 
devices (~400V)  need 5-6 volts for solid gate turn-on, yet logic-levels on 
most micro-controllers and FPGAs are only 1.2 to 3.3volts.  That leaves a 
few options:

1. Use high-voltage logic, such as 4000-series CMOS, to drive HV NMOS. My 
first nixie clock does this.

2. Use NPN drivers; you can easily design constant-current drivers running 
from 3.3V. I've used surface-mount devices with 2 NPNs inside, and they are 
rated at 250V.

3. Use a level-shifter between your logic and the driver. I'm doing this on 
my current design with a HV5530.

4. Find a device with a low-voltage gate. Good luck on this; most 
logic-levels NMOS devices only handle 60V or less. If you also want low Rds 
(necessary for DC-DC converters), you have even fewer options.

5. Pull-up resistor. Ugghhh... It will work, but you will burn more power. 
Could be dangerous for a DC-DC converter if the logic/software turning off 
the gate goes haywire, which would lead to large current/burnout.


I advise against relying upon the voltage-drop of the nixie tube to protect 
the driver, though this is commonly done with designs using the 74141. I 
always select my driver to handle the maximum-possible anode supply, and 
add margin above that. I've never had a fried driver, ghosting, etc. 
Parasitic capacitance and leakage can stress drivers above their maximum 
ratings, which will lead to premature failure.

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