There are lots of inexpensive isolated DC-DC converters. I've been using 
products from Cui and Recom. Here's a 12V unit I use: 
http://www.digikey.com/product-detail/en/VIBLSD1-S5-S12-SIP/102-1432-ND/989887

They are available in all sorts of input and output voltages. Be careful 
that some require a *minimum* load, which can be for driving a power-on LED 
indicator. Also be careful filter caps on the output; they often have 
max-cap limits in the datasheet.

Anyways, they are easy to use. Connect the 2 input pins to your low-voltage 
supply observing correct polairty.
For the DC-DC converter outputs, connect the *positive* terminal to your 
anode supply; the negative output becomes the bias supply for your current 
regulator(s).

To make the anode current adjustable, connect a pot across the DCDC 
converter's output, then use the wiper to supply the bias voltage. I'd 
suggest 10-turn trimmers, rather than standard (cheap) 3/4 turn.

   - If you are using PNPs, be mindful of the base current. It may force 
   you to use lower-value potentiometers (ie,below 1K).
   - If you use PMOS, there is no current so just use any pot you have; 
   anything from 1K to 100K or more is fine. Best to add a zener diode to 
   clamp any potential voltage spikes that could happen (startup/shutdown 
   transients, ESD, etc) to protect the PMOS. The zener voltage needs to be 
   greater than the DC-DC converters output voltage, AND less than the max Vgs 
   specified in the PMOS datasheet.

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