Thanks all for the wonderful input and confirming cathode current limiters 
is a valid replacement for passive anode current limiting, even though the 
latter is far more common. Despite the active cathode current limiters 
requiring more parts and cost, the benefits are worth it for the projects I 
have in mind.

Side note, good looking Sperry SP-151 display you have there Robert L. The 
rectangluar neon segment displays always looked awesome to me.

Additionally, good call on the pull-down resistor, that was indeed an extra 
part added to make sure the simulation worked correctly. In reality 595 
outputs will a controlled high or low and never set to the High-Z state. 
Hence pull-down not needed in reality as pointed out.

To give some added background, I want to add IN-12 or other common Nixie 
tubes to devices that already have high voltage supplies. In practice if 
some vintage hardware is already rectifying grid power to create high 
voltage DC source generally 25mA can be siphoned off for a Nixie display 
and not affect the vintage device. Of course exact implementation 
will assessed on a case by case bases for best results.

Thanks again for the input everyone,

Allen

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