mark
i know how to do it in excel. but, excel is the saturn next to my
porsche (R).
dennis
Dennis Fisher MD
P < (The "P Less Than" Company)
Phone: 1-866-PLessThan (1-866-753-7784)
Fax: 1-415-564-2220
www.PLessThan.com
On Feb 28, 2007, at 6:42 AM, Mark Sale - Next Level Solutions wrote:
Dennis,
I'll show you how to do it in Excel someday. But the answer is to
use
the SUBPROBLEMS option in the SIMULATION record
SUBPROBLEMS=n
Requests that the entire NONMEM problem is to be repeated n times
in succession (including all NONMEM steps: simulation, estima-
tion, covariance, table, scatterplot). Each subproblem includes
the Simulation Step, but the random sources are simply continued
from subproblem to subproblem. If n=0 or n=1, there is only one
subproblem; this is the default. May also be coded SUBPROBS,
NSUBPROBLEMS, NSUBPROBS.
Mark Sale MD
Next Level Solutions, LLC
www.NextLevelSolns.com
-------- Original Message --------
Subject: Re: [NMusers] create simulation file for 5000 patients ?
From: "navin goyal" <[EMAIL PROTECTED]>
Date: Tue, February 27, 2007 10:28 pm
To: "Dennis Fisher" <[EMAIL PROTECTED]>, [email protected]
thanks for the reply.
Could excel help me if I had less patients say around 100-200.
I mean.. could i generate an excel file then ??
How could I do it ??
Thanks again.
Navin
On 2/27/07, Dennis Fisher <[EMAIL PROTECTED]> wrote: use R or
Splus
Excel would be a disaster - it is capped at ~ 64000 lines.
Dennis Fisher MD P < (The "P Less Than" Company) Phone: 1-866-
PLessThan (1-866-753-7784) Fax: 1-415-564-2220 www.PLessThan.com
On Feb 27, 2007, at 1:39 PM, navin goyal wrote:
Hello everybody,
I am trying to simulate PKPD data for 5000 patients, with each
patient having around 100 time points.
How could I create a data file for this simulation??
Any help is appreciated.
Thanks
Navin
