Hi, I am using ADVAN 6 to do some PKPD modeling and got this error message: NUMERICAL DIFFICULTIES WITH INTEGRATION ROUTINE.
MAXIMUM NO. OF EVALUATIONS OF DIFFERENTIAL EQUATIONS, 1000000, EXCEEDED. I know in NONMEM 6 you may use following code to increase maximum number of integration of differential equation: "FIRST " COMMON /PRCOMG/ IDUM1,IDUM2,IMAX,IDUM4,IDUM5 " INTEGER IDUM1,IDUM2,IMAX,IDUM4,IDUM5 " IMAX=100000000 But in NONMEM 7 it gave error message: (WARNING 113) VERBATIM CODE CONTAINS "COMMON". IF THIS IS NOT A USER-DEFINED COMMON, IT SHOULD BE REPLACED BY THE APPROPRIATE MODULE. CREATING MUMODEL ROUTINE... Thus, how can I increase maximum number of integration of differential equation in NONMEM 7? Thank you. lili
