Hi Jan
 
I've just checked Hale (2002).  This medication is approved by the American Academy of Paediatrics for use in b/f mothers.
In a study of 9 pts given 400 mg doses the infant dose correlated to 0.025% of the maternal dose.  No problems have been reported, but infant should be monitored for thyroid function (T4 TSH) during therapy.  Lactation risk is L2 which means "it has been studied in a limited number of women without an increase in adverse effects in the infant.  And/or the evidence of a demonstrated risk which is likely to follow use of this medication in a breasfeeding woman is remote."
Joy
 
Joy Cocks RN (Div 1) RM CBE IBCLC
BRIGHT Vic 3741
email:[EMAIL PROTECTED]
----- Original Message -----
Sent: Tuesday, October 21, 2003 15:26 PM
Subject: [ozmidwifery] graves disease and breastfeeding

I have a client who has graves disease. She is taking 3 50 mgs propylthiouracil 3 times a day. I would like to know if anyone has any information regarding the effects this medication may have on breastfeeding a 7 week old boy. The boy has no thyroid problems. Also, if this medication is increased will there be any effects on the breastfeeding.
 
Thanks for any help you can give me.jan
 

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