If you have a pituitary tumor, your doctor is basically saying that your pitutiary is not releasing the LH and FSH hormones correctly and therefore, your ovaries are not functioning properly. Untreated, this could lead to osteoporosis. Per the article below, you can also have some other unpleasant symptoms, such as hot flashes and sweating. Psychological symptoms inclue anxiety, emotional lability and irritability. Urinary symptoms may include Genitourinary symptoms include dyspareunia (painful intercourse), increased vaginal infections, urgency of micturition (having to urinate alot). "Female hypogonadism may be due to either hypothalamic-pituitary defect or primary gonadal defect. 1) The commonest presentation of sex hormone disorder in females is amenorrhoea or absence of menstruation. This can be primary and secondary. Primary amenorrhoea may be due to hypothalamic or pituitary lesion where the necessary releasing hormone or gonadotrophin is lacking resulting in absence of necessary of sex hormones. Structural abnormalities of the female genital tract need to be excluded. Certain chronic systemic diseases may effect the normal release of ovarian hormones and may delay the onset of menstruation. Secondary amenorrhoea is a relatively common problem. This may occur due to anorexia nervosa or secondarily due to underlying chronic diseases like tuberculosis, malignancy or hyperthyroidism. The above mentioned cases primarily has got loss of weight. The reverse condition i.e. massive weight gain may suggest Cushing's syndrome, hypothyroidism, etc. in case of secondary amenorrhoea. Another seual hormonal disorder is hirsutism - occuring as a result of excess androgen ( commonly found in case of polycystic ovarian syndrome). Often excess androgen from androgen secreting tumours(rarely found) produce virilisation i.e. deepening of voice, breast atrophy, clitoromegaly apart from amenorrhoea. MENOPAUSE is the commonest cause of secondary amenorrhoea occurring in the life of every woman at around 45 years(+ 5 years,-5 years). Menopause is a normal phenomenon where the menses cease to flow after that certain age but there are some patients whose menopause is associated with major problems: Vasomotor symptoms include hot flushes, sweating. Psychologically the patient suffers from anxiety, emotional lability and irritability. Genitourinary symptoms include dysperaunia, increased vaginal infections, urgency of micturition. Fall in oestrogen secretion is associated with increased bone resorption i.e. loss of bone mass which eventually result in osteoporosis with an increased incidence of vertebral compression fracture, fractured neck of femur and distal radius in comparison to the male." http://www.homeoint.org/site/classhom/sexhormonal.htm You can read more here: E-Medicine: Here is a link to the Pituitary Foundation that lists the hormone replacement drugs: Your doctor could put you on a combination of drugs that improves your quality of life and reduces your risk for cancer. Read up on the published studies so that you can be an informed patient when talking with our doctor. The benefits may outweigh the risks in a hypopituitary woman of your age. Good luck and good health! Minnie | 