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New Message on Pituitary Chat

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From: hope1112
Message 4 in Discussion

Hi, Rissy1101, I've been taking bromocriptine for 10 years for a 
microprolactinoma. My really bad side effects went away after about a month, so 
hang in there.  The side effect that did not leave was stuffy nose but I find 
if I break the pill up in many smaller doses over the day, the impact isn't as 
bad.  The first time I was prescribed this drug, I took the whole 2.5 mg. at 
once, like my doctor stupidly suggested.  I felt as if I was going to pass out, 
my knees buckled, and I couldn't breath at all through my nose.  When I 
reported this to the endocrinologist, he told me not to take it anymore because 
of the side effects.  So I didn't and spent many years merely on estrogen 
replacement therapy because the high prolactin lowers estrogen.  But I was 
scared of possible cancer from the hormone therapy, so I found another 
endocrinologist who told me to take the 2.5 mg. tablet and break it into 
quarters.  She said to take 1 quarter for 1-2 weeks, then add another quarter 
for 1-2 weeks, etc. By the time I was up to 3/4 of a 2.5 mg. tablet, my period 
came back, so I had a blood test and my prolactin level was around 20 or so.  
Because it normalized, I did not feel I had to add another quarter tablet.  So 
3/4 of a 2.5 mg. tablet worked for me for 10 years. Taking the full amount at 
night orally, with food (without food really stuffed up my nose,) worked for me 
for a long time, until I developed really bad allergies 2 years ago which 
stuffed my nose up horribly and did not allow me to sleep at night, when my 
nose closed up the most.  So I take my dose now during the day, which does make 
me a bit tired, for about 2-3 hours, when the pill seems to peak.  It seems to 
take 2-3 hours to peak, and the episode lasts 2-3 hours but then gets better.  
I drink some coffee to get me through that.  But if you don't have allergies 
that hurt your breathing at night, eventually being able to take the full dose 
at night would be best.  I've find Breathe Right nasal strips help. Hope that 
helps.   Also, to answer about the link to lactation and thinning of the bones, 
unfortunately there is a link to high prolactin levels (which causes lactation) 
and osteoporosis. But if you control your prolactin levels with the bromo, your 
estrogen levels should normalize which will help your bones.  (High prolactin 
lowers estrogen, and lack of estrogen can thin your bones)  I would recommend 
taking a good calcium-magnesium-vitamin D supplement to help with the bone 
issue. This is what I have heard, but you should ask your doctor.   All the 
best, Cathy

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