I will make AnnotationDB later, but for the variation analysis, in order to
save sequence information, I prefer pairwise NLMSA only for the nucleotides
that has been changed during sequencing. It would be better to have only one
NLMSA, but I rather choose to have two NLMSA (AnnotationDB & pairwise NLMSA)
for now. AnnotationDB for coverage and gene analysis and pairwise NLMSA for
variation analysis.
Do you think it is a good idea? I agree that it is kind of inelegant to have
two NLMSA... But I was afraid that the input files will be very big...

Namshin Kim



On Mon, Jun 29, 2009 at 12:06 PM, C. Titus Brown <[email protected]> wrote:

>
> On Mon, Jun 29, 2009 at 11:20:53AM +0900, Namshin Kim wrote:
> -> No. I am building pairwise NLMSA from custom-made axtNet files. axtFiles
> are
> -> not that big but there are 14m sequences in it. It would take 2-3 hours
> for
> -> pygr to make .idDict and .seqIDdict.
>
> ahh, I see.  is that how you'd recommend doing this sort of thing, then?
> transforming the input first? seems kind of inelegant...
>
> --t
>
> >
>

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