Hi Soren,

Take a look at PhyloSim (http://bit.ly/psim-cran, http://bit.ly/phylosim),
especially at chapter 2.6 (Simulating heterotachy) of the vignette (
http://bit.ly/psim-doc).

Regards,
Botond



On Tue, Aug 13, 2013 at 3:19 PM, Søren Faurby <[email protected]>wrote:

> Hi All,
>
> I am trying to simulate sequence evolution where the underlying parameters
> such as the Transition/Transversion Ratio and GC-content change over time
> in each lineage for instance via Brownian motion (but other models may also
> be acceptable).
>
> Can anyone point me to any codes capable of doing this within or outside R.
>
> Kind regards,
> Søren Faurby
>
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>
>
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-- 
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