Based on supporting similar Optiplexes: is there a chance that "low power mode" 
is set to "off" in the BIOS and/or "Wake on LAN" is set to "on"? Screenshot 
here:

http://www.itninja.com/uploads/images/22659/yEx4RP.jpg?1363380277845

http://www.itninja.com/uploads/images/22659/EmtLX4.jpg?1363380296775

Check that there are no USB-specific settings in the BIOS, too. I doubt there 
are but while you're there…

FWIW we're using Supermicro chassis/mainboard/PSU components (Intel Xeons) for 
our 7 Rivendell systems (soon to be 9). But our first test box was a recycled 
Optiplex 745 small-form-factor desktop, which shouldn't be too different from 
your 740 (guessing here based on the 745s, 755s, 760s, and 780s we have). Want 
to rackmount everything in a central place? Instead of KVM runs, try a Teradici 
PCoIP card from eVGA and a PCoIP thin-client box in the studio. We've done this 
and it rocks. No drivers needed unless you need a USB CD-ROM drive at the 
thin-client box (we have remote-start CD players in the chain via the audio 
router, so that was not needed for our setup).

You might check the mainboard for bulging caps like someone else suggested -- 
might try running a Linux-based "live" CD of some other flavor of Linux to 
ensure it isn't your particular distro.

--
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On 04/04/14 16:58, Larry wrote:
Larry <larry@...> writes:

I have searched the archives and no one else has posted this problem
that
I can find. I have installed the Paravel broadcast automation appliance
this week and the mouse will freeze/stop working after just a few
minutes
of use. I have to reboot to get the mouse back but it always freezes. I
have installed this on a Dell Optiplex 740 dual core 64 bit processor,
2GB
Ram, 1TB hard drive, ALSA compatible M-Audio Delta 44 sound card and USB
mouse and keyboard. After the mouse freezes the USB keyboard will still
work using the up/down and F keys but the mouse stops no matter what USB
port I use. Appreciate any help.
This Dell Optiplex 740 has been running Windows XP reliably with the same
mouse and keyboard since 2009. I have tried 2 different mice and they are
USB and it is not the mouse. I have figured out the problem is all the USB
ports go dead when this happens. When the mouse the stops, the keyboard
works for a while but If I unplug keyboard and plug it back in it will no
longer work at all. Nothing works in any of the USB ports after the mouse
stops. I have tried re-installing the appliance, removing the sound card,
removing memory one stick at a time and the video card and the USB ports
will stop working. I have downgraded the BIOS to 4 former versions and
that makes no difference. There must be something in this Dell chipset
that is conflicting with CentOS. Nothing shows up in dmesg or
the /var/log/messages file. My next step will be downgrading the the
version 1 appliance but I don't have high hopes.

What brand and model computer are you guys using that have success with
Rivendell Appliance?
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