Re: Killings, evil and pictures to assure accountabillity was, Re: The Mercies of The Vatican

2004-08-31 Thread Doug Pensinger
Dan wrote:
I realize that this involves a switch in worldview because most of us 
were taught a convenient fiction in school.  I certainly believed that 
the
Nazi's had a police state, even for the Ayrians, from the start.  I 
thought the Holocaust was very secret.  But now, I accept the evidence 
that Nazi
Germany was not a police state and the Holocaust was not all that hidden.
Even if the Holocaust wasn't hidden, was there a mechanism for protest?  
Could someone have voiced their objections with impunity.  Written a 
letter to the editor?  Staged a protest?  The idea seems rather ludicrous 
to me especially in view of the fact that their country was at war 
assumedly with the rights restrictions that are normally present in such 
cases.

I'm not taking sides, BTW, but I'd be interested in further reading on 
this if anyone has a reference.

--
Doug
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Re: A pox on both your houses

2004-08-31 Thread Gary Denton
On Mon, 30 Aug 2004 22:56:49 -0500, Dan Minette
[EMAIL PROTECTED] wrote:
 
 
 
 - Original Message -
 From: Julia Randolph [EMAIL PROTECTED]
 To: Killer Bs Discussion [EMAIL PROTECTED]
 Sent: Monday, August 30, 2004 10:05 PM
 Subject: Re: A pox on both your houses
 
  Where might one find the entire article, so as to read it in its
  entirety and draw one's own conclusions?
 
 That's what I obtained from my friend.  I'm pretty sure that's the entire
 article.
 
 Dan M.

   
washingtonpost.com 
The Other Candidate Bounce 

http://www.washingtonpost.com/ac2/wp-dyn/A50944-2004Aug8?language=printer

F*GI

gary
-- 
#2 on google for liberal news
I don't try harder
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Re: Killings, evil and pictures to assure accountabillity L3

2004-08-31 Thread Sonja van Baardwijk-Holten
Dan Minette wrote:
- Original Message - 
From: Sonja van Baardwijk-Holten [EMAIL PROTECTED]
To: Killer Bs Discussion [EMAIL PROTECTED]
Sent: Sunday, August 29, 2004 7:55 PM
Subject: Re: Killings, evil and pictures to assure accountabillity was, Re:
The Mercies of The Vatican

 

Gautam Mukunda wrote:
   

Sonja, I'll make you a deal.  If you stop making
excuses for people who participated in the Holocaust,
I'll stop calling you on it when you do it.

 

No deal. Your basic presumption is flawed. Not every German during the
holocaust was automatically and without exception a participant in the
holocaust and a jew murdering nazi.
   

Not every one, probably not.  But, it was common knowledge and there was no
indication of public horror at it.  As Gautam said, it wasn't accidental;
it was deliberate policy from on high.
 

My point is that the lack of public horror wasn't contained or even 
exclusive to Germany. Europe, the US and the rest of the world were 
similarly disinterested in the stories of persecutions that did the 
rounds. I hold that it is too easy to dismiss a horror story (perhaps 
also because of the fact that the scope and magnitude these crimes were 
perpetrated on, up untill then, were totally unheard of) when you 
haven't got physical evidence as in f.i. pictures, portraying the actual 
magnitude of violence happening. I mean would you have believed Abu 
Graihb or believed that it was that severe if you'd not seen pictures of 
it? Would there have been a similar outcry? Up until a point in the war, 
the world simply didn't have an interest and without physical proof and 
ready available pictures/physical proof there was no incentive to change 
this attitude in what happened because it was convenient, not on their 
doorstep and basically at the time without solid irrefutable widespread 
proof.

I've read your arguements on this type of subject for a while, and I've
seen a pattern that I'd like some feedback on.  Consistancy, you lump all
bad outcomes together.  What happened in Abu Ghraib was wrong.  People
should be punished; and that includes officers who were derelict in their
duty to provide the proper environment.  You saw my opinion expressed in my
recent post.
Having said that; there is no comparison with this and genocide.
Genocide starts with that first murder, the first act against a fellow 
human. So I feel that there is room for thought experiments and comparison.

One was, IMHO, a criminal neglect to establish a proper prison environment, where the 
long established procedure was not enforced.  The second was a
systematic, well planned slaughter of millions of innocent humans that
gained momentum as new, more efficent murder techniques were developed.
Information about this, according to documentation from the time, was
readily available to the average citizen.
Actually here we differ considerably. It wasn't mere neglect that caused 
it, to me it was a premeditated and consiously carried out policy of 
establishing superiority toward what are considered inferior peoples, at 
all cost. So the intent factor and the underlying potential for worse, 
to me makes it really bad.

In the US, there was a hue and cry about the crimes.  It may very well be
that we will not sufficiently punish people far enough up the chain of
command, but it is also clear that a number of pro-military people in the
US are mad as hell that things were not done right.
 

As always only some, not all. There are those that are even madder at 
the story getting out in the first place, and I'm not so sure that the 
displayed outrage for some isn't a mere saving face gesture. Of course 
there are those that are truely outraged so there is still hope for the 
future, although the edict to forbid camera's in the army isn't exactly 
inspiring much confidence. :o)

I have not seen an acknowledgement of the multiple order of magnitude in
the difference between these two things.  To me, its like comparing a
mother who yells at her kids when she shouldn't because she is upset about
something else and a mother who burns her kids with a cigarette.  Both are
wrong, but the order of magnitude of the wrongs are enormously different.
 

There is a magnitude of difference, but do I have to acknowledge that 
everytime I breach the subject. To me it is just as offensive to lump 
all people on the BADEVIL heap each time something controversial on US 
behaviour is mentioned on Brin-L. If I'd wanted I could construe that 
into something along the lines of being a denyer and defender for 
massacres committed in the name of the US and it's believes. But I don't 
since I do understand there is a difference.

It seems to me that you differ with this idea.  Bad is bad, wrong is wrong,
and there is no worse.
 

Indeed, bad is bad and wrong is wrong. To me the *only* difference is 
the magnitude and the scale. Maybe that's what's offensive, I don't know.

The difficutly with this is that it lumps all non perfect things 

Re: Privately funded medical research is evil, why it must be eradicated [was: Fascist Censorship Spreads: Vichy Style]

2004-08-31 Thread Erik Reuter
On Mon, Aug 30, 2004 at 06:13:40PM -0700, Gautam Mukunda wrote:
 --- Dan Minette [EMAIL PROTECTED] wrote:
  My numbers indicate that about 20% of the cost of
  drugs goes into
  development, cost and production, and that the rest
  is systematic overhead.
 
 I can't comment on this much (for obvious reasons).  I

Not so obvious, actually. There is plenty of publicly available
information. I haven't studied the drug industry, but here is a very
short look at some numbers from the income statements of a few:

20022003   20032003 TOTALTOTAL % 
 PFEMRK ABT LLY  OF SALES

Revenue32373   22486   19681   1258287122 100.0
COGS404543159473267520508  23.5

Gross Profit   28328   18171   10207990766613  76.5

Operating Expenses
SGA   1084663955051405526347  30.2
RD 517632801834235012640  14.5
Other630   (1106)  0   0 (476) (0.5)

Operating  1167690833322350227583  31.7
Income 

Other Income and Expenses
Interest Inc 120 419 412(240) 711   0.8
Taxes   26092433 981 701 6724   7.7

Net Income  912667392753256121179  24.3


I'm not going to try to explain all of the accounting conventions above
to those who aren't familiar with them (but I will answer specific
questions). But briefly, my way of looking at it is to start with Sales
and look at everything else as a percentage of Sales.  I added up the
income statement numbers for Pfizer, Merck, Abbott, and Lilly as shown
above.

Total revenues were $87B. Cost of goods sold accounted for 23.5% of
revenues. Sales, general, and administrative used up 30.2% of revenue,
and research and development used of 14.5% of revenue. Unlike most
companies these days, the drug companies are cash machines with little
debt -- they actually EARNED 0.8% of sales as interest income (most
other companies pay interest on their debt). They paid 7.7% of revenues
as taxes, leaving a net profit margin of 24.3% (quite exceptional, few
companies are so high).

To summarize the major components of where revenue went:

 23.5%  COGS
 30.2%  SGA
 14.5%  RD
  7.7%  Tax
 24.3%  Net Income
--
100.2%  TOTAL (not 100% since I left out a few small numbers)

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The McCain Fizzle

2004-08-31 Thread The Fool
http://www.thenation.com/capitalgames/index.mhtml?bid=3pid=1732

Mccain'll never win the GOP presidential primary.
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RE: The Next Superpower Re: AIDs in Africa

2004-08-31 Thread Ritu

JDG wrote:

 In terms of China running into potential instability 
 vis-a-vis a Civil War or Taiwan, the risks of this strike me 
 as on balance only marginally greater than the potential 
 risks of India running into instability
 vis-a-vis a Civil War of their own, or else a 
 Pakistan-Kashmir crisis.   

What would a Pakistan-Kashmir crisis entail, and what would drive India
to civil war?
I'd like to hear more. :)

Ritu
GCU Curious

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New iMac

2004-08-31 Thread William T Goodall
http://www.apple.com/imac/
I predict this one will sell better than the desk-lamp one because it 
looks more normal...

--
William T Goodall
Mail : [EMAIL PROTECTED]
Web  : http://www.wtgab.demon.co.uk
Blog : http://radio.weblogs.com/0111221/
Our products just aren't engineered for security. - Brian Valentine, 
senior vice president in charge of Microsoft's Windows development 
team.

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Re: Privately funded medical research is evil, why it must be eradicated [was: Fascist Censorship Spreads: Vichy Style]

2004-08-31 Thread Gautam Mukunda
--- Erik Reuter [EMAIL PROTECTED] wrote:

 On Mon, Aug 30, 2004 at 06:13:40PM -0700, Gautam
 Mukunda wrote:
  I can't comment on this much (for obvious
 reasons).  I
 
 Not so obvious, actually. 

All right.  The reason is that I spent most of the
last two years working as a consultant to several
companies in the pharmaceutical industry and therefore
am not allowed to comment on the details of their
financial performance, because much of what I saw
during that time is confidential (that is, I would be
in violation of confidentiality agreements).  Does
that make it clear?

=
Gautam Mukunda
[EMAIL PROTECTED]
Freedom is not free
http://www.mukunda.blogspot.com



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James Doohan bids farewell to fans

2004-08-31 Thread Bryon Daly
I had no idea that James Doohan was suffering from both Alzheimer's
and Parkinson's disease.  Wow, that's rough.


http://www.trektoday.com/news/300804_02.shtml


Doohan Bids Farewell To Fans
August 30, 2004 - 9:57 PM

James Doohan said farewell to the world of Star Trek this weekend at a
convention in his honour entitled Beam Me Up Scotty, attended by the
entire living cast of the original series and leading up to the
ceremony on Tuesday at which he will be given a star on the Hollywood
Walk of Fame. Though ailing, Doohan was reportedly in high spirits for
this final round of public appearances, attended by fans as well as
actors, family members and an astronaut.

The Associated Press (via The Mercury News) reported that the
84-year-old Scotty actor blew kisses to fans during events held to
benefit a research foundation for Alzheimer's disease, from which
Doohan suffers. The actor's son Chris Doohan credited Star Trek fans
with helping raise money for the actor's star.

The Los Angeles Times' Richard Fausset wrote from a ballroom at the
Renaissance Hollywood Hotel that the denizens of this peculiar
universe stood united: the valiant Starfleet commanders, the fierce
Romulan warriors, the pimply speculators in the action figure market,
noting that fans had paid up to $995 to take part in the two-day
convention, where Doohan - suffering from Parkinson's disease as well
- spoke at a news conference and circulated among fans.

Some of the hundreds who made the trip for the chance to see him one
last time said they paid the admission because over the years, the man
they knew as Scotty always took the time to talk to them, sign
autographs and chat about alternate universes, obscure plot points and
spaceship specs, Fausset said. Chris Doohan observed that while many
actors become upset about typecasting, that didn't concern him,
because he was typecast as Scotty...it's been his bread and butter.

TrekWeb has posted a report sent in by a fan, who first visited the
dealer's room and saw Roddenberry On Patrol and the auction at which
Doohan's outfit from Star Trek IV: The Voyage Home. Then William
Shatner (Kirk) and Leonard Nimoy (Spock) held a panel at which they
insult[ed] each other for an hour, with Nimoy joking about Shatner's
weight and Shatner claiming that when he named a price for appearing
on Star Trek: Enterprise, the producers seemed less interested in
having him appear. After a taped tribute, Doohan himself appeared in a
motorized wheelchair with his family and was greeted by astronaut Neil
Armstrong.

Planet Xpo put on the convention last weekend. Doohan will receive his
star in front of the Hollywood Entertainment Museum at 7021 Hollywood
Boulevard at 10:30 a.m. on Tuesday.
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Re: Privately funded medical research is evil, why it must be eradicated [was: Fascist Censorship Spreads: Vichy Style]

2004-08-31 Thread Erik Reuter
On Tue, Aug 31, 2004 at 07:05:23AM -0700, Gautam Mukunda wrote:

 --- Erik Reuter [EMAIL PROTECTED] wrote:

  Not so obvious, actually.

 All right.  The reason is that I spent most of the last two years
 working as a consultant to several companies in the pharmaceutical
 industry and therefore am not allowed to comment on the details
 of their financial performance, because much of what I saw during
 that time is confidential (that is, I would be in violation of
 confidentiality agreements).  Does that make it clear?

It was clear what you meant before your clarification, just not
relevant. You can obviously comment on publicly available information,
of which there is a great deal, as I posted. Acting like you know a
lot about a subject based on secret information that you can't share
may score points in the consultant world, but not here, especially
when you are disputing someone else's point who isn't claiming secret
information.


-- 
Erik Reuter   http://www.erikreuter.net/
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reply to msg 49 re: new drug development

2004-08-31 Thread kate sisco
Exerpt msg 49 post:
I really don't disagree with you concerning the problems inherent in
demanding cheap AIDs drugs, one way or another, we need to pay for the
research and development.  But, putting my rational advisor hat on, I'd
argue that a successful drug company should do no real breakthrough
developments.  Rather, is should focus on developing patentable small
variations in the chemical compound already used.  Look for small
advantages, and then market the heck out of them.  The development 
risks
are minimal, as are the market risks.  Indeed, from what I've read, 
this is
the model drug companies are going to.  Its not that they wouldn't 
market a
cure; its that, when ideas are pitched, the low risk higher gain ideas 
will
get the money first.
 
I have seen figures that say 60% of new drugs are existing drugs whose patent is 
about to expire and become public domain.  The companies tinker with the formula in a 
small way and market a new drug, again covered under patent rights.  I am not familiar 
with the ins and out of the current argument so perhaps I should not comment rather 
than be exposed for an uninformed layman, but doesn't this type of action have the 
consequence of supressing new discoveries that could lay in other areas than drug 
development?


ks 
http//:www.chequamegon.blogspot.com


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Re: reply to msg 49 re: new drug development

2004-08-31 Thread Gautam Mukunda
--- kate sisco [EMAIL PROTECTED] wrote:
 I have seen figures that say 60% of new drugs are
 existing drugs whose patent is about to expire and
 become public domain.  The companies tinker with the
 formula in a small way and market a new drug, again
 covered under patent rights.  I am not familiar with
 the ins and out of the current argument so perhaps I
 should not comment rather than be exposed for an
 uninformed layman, but doesn't this type of action
 have the consequence of supressing new discoveries
 that could lay in other areas than drug development?
 
 ks 

Well, the issue here is that in this situation the old
drug has gone off patent and gone generic.  So if
there's no therapeutic benefit for the new drug then
it's a doctor's responsibility to prescribe the old
one.  Once a drug's patent has been filed, then the
clock is ticking on its lifespan.  That drug will go
generic and nothing is going to stop that.  So yes,
lots of drug companies try this tactic, but unless the
altered drug is therapeutically superior to the
earlier one, it doesn't work very well at all.  And
isn't the purpose of the system to reward new,
therapeutically superior drugs?

=
Gautam Mukunda
[EMAIL PROTECTED]
Freedom is not free
http://www.mukunda.blogspot.com




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Re: The McCain Fizzle

2004-08-31 Thread Bryon Daly
On Tue, 31 Aug 2004 06:02:53 -0500, The Fool [EMAIL PROTECTED] wrote:
 http://www.thenation.com/capitalgames/index.mhtml?bid=3pid=1732
 
 Mccain'll never win the GOP presidential primary.

I don't think so either.  I think despite McCain's loyalty to the
party in campaigning for and endorsing Bush (and rejecting the Kerry
VP offer), he will be remembered by the Republicans far more for his
few small disloyalties like his assorted criticisms of Bush over the
years, his weak Bush endorsement, and words of praise for Kerry.
Given the close race, I think that these small things will be given
exagerated weight, and he will be a major scapegoat if Bush loses.
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Re: The McCain Fizzle

2004-08-31 Thread Bryon Daly
Gah - I'm having some send issues here - my apologies if this
message gets sent more than once!

On Tue, 31 Aug 2004 06:02:53 -0500, The Fool [EMAIL PROTECTED] wrote:
 http://www.thenation.com/capitalgames/index.mhtml?bid=3pid=1732
 
 Mccain'll never win the GOP presidential primary.

I don't think so either.  I think despite McCain's loyalty to the
party in campaigning for and endorsing Bush (and rejecting the Kerry
VP offer), he will be remembered by the Republicans far more for his
few small disloyalties like his assorted criticisms of Bush over the
years, his weak Bush endorsement, and words of praise for Kerry.
Given the close race, I think that these small things will be given
exagerated weight, and he will be a major scapegoat if Bush loses.
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Re: Privately funded medical research is evil, why it must be eradicated [was: Fascist Censorship Spreads: Vichy Style]

2004-08-31 Thread Gautam Mukunda
--- Erik Reuter [EMAIL PROTECTED] wrote:
 It was clear what you meant before your
 clarification, just not
 relevant. You can obviously comment on publicly
 available information,
 of which there is a great deal, as I posted. Acting
 like you know a
 lot about a subject based on secret information that
 you can't share
 may score points in the consultant world, but not
 here, especially
 when you are disputing someone else's point who
 isn't claiming secret
 information.

Well, Erik, I guess I'll have to live with your
disapproval...forgive me while I sob.  Anyone who read
what I wrote might note:
1. I disputed it only to the point that I thought it
was a little low
2. It was neither germane nor significant to the
discussion

If, at some point in the future, someone trusts you
with a job that involves decisions and information
that have to be handled responsibly, perhaps you will
understand where I'm coming from.

=
Gautam Mukunda
[EMAIL PROTECTED]
Freedom is not free
http://www.mukunda.blogspot.com




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Re: Privately funded medical research is evil, why it must be eradicated

2004-08-31 Thread Alberto Monteiro
Gautam Mukunda wrote:

 Well, Erik, I guess I'll have to live with your
 disapproval...forgive me while I sob.  Anyone who read
 what I wrote might note:
 1. I disputed it only to the point that I thought it
 was a little low

I agree, there was no dispute, because we both agree on this
subject - except that what Gautam points as an orientation
for the future...

  As a purely rational advisor to the industry, I would
  tell them it was the dumbest mistake they ever made,
  though.  Any pharmaco that invested in AIDS research
  and got a success out of it got _screwed_.  I would
  use a harsher word, but I know how it bothers John. 
  They took enormous publicity hits, and then were
  forced to sell it at a very low price.  From a
  business standpoint, any pharmaco that invested in
  AIDS twenty years ago made a mistake.  Any pharmaco
  that did it today would have to be run by idiots or
  saints, and the reason why is precisely the attitudes
  you describe.

... I claim that has _already_ been oriented to them
in the past 50 or so years, where _no_ significant
disease has found a final _cure_.

Alberto Monteiro

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Re: thinking about free will

2004-08-31 Thread Dave Land
Folks,
From the posts I've seen on this list, I'm guessing that not too many 
here hold with Harvard psychologist Steven Pinker, who rejects both 
what he calls the naturalistic fallacy (the belief that if something 
is natural, it must be good) and the moralistic fallacy (the belief 
that moral traits arise from nature).

Pinker asserts that human values do not arise from nature, but in 
/spite/ of nature. Nature is what we are put here on this earth to 
rise above, he says, begging the question as to who or what put us 
here in the first place.

Dave
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Re: Privately funded medical research is evil, why it must be eradicated

2004-08-31 Thread Gautam Mukunda
--- Alberto Monteiro [EMAIL PROTECTED] wrote:
 ... I claim that has _already_ been oriented to them
 in the past 50 or so years, where _no_ significant
 disease has found a final _cure_.
 
 Alberto Monteiro

The problem, Alberto, is that the antibiotics were
discovered a little bit before that.  Anti-viral
research is hard.  No one has ever succeeded at that. 
Why, exactly, do you blame the pharma companies for
not succeeding in doing something that no one has ever
succeeded in doing?  They have successfully managed to
cure every bacterial disease - that's a pretty good
record.

Also, btw, you're completely ignoring the enormous
progress that has been made against (for example)
cancer.  A generation ago (I don't remember the exact
numbers, but these will be roughly correct) the
majority of pediatric cancer patients died.  Now it's
under a quarter.  Almost all of that improvement is
due to the work of the pharmaceutical companies, and
that's just a beginning.

So if your argument is We can't beat cancer with one
pill, and I blame the pharmacos, well, blame them all
you want, but unless you want to point out to me the
huge medical advances that (for example) the Soviet
Union made I think you've got a pretty difficult
situation trying to prove that this is because of a
choice on their part.

As the chief of RD at a very large pharmaco said in
an interview a couple of weeks ago - This isn't
rocket science.  This is _much harder_ than rocket
science.  You can see a rocket.  You know exactly how
a rocket works.  We don't (for example) understand the
liver at all well - we barely understand it at all,
really.  Drug development is harder now because all of
the low-hanging fruit - the bacterial diseases and the
easy vaccines, basically - have already been plucked. 
Now the really hard slog is there.  Despite that fact,
the same pharma companies that you criticize have
managed to change AIDS from a fatal to chronic disease
and improve the survival rates for most forms of
cancer by _multiples_.  Do you think that was _easy_? 
Merck has more Nobel prize winners on staff than most
universities - they didn't win all of those because
they do poor work.  They won them because they do
extraordinary work on exceptionally difficult areas of research.

=
Gautam Mukunda
[EMAIL PROTECTED]
Freedom is not free
http://www.mukunda.blogspot.com



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Re: Privately funded medical research is evil, why it must be eradicated

2004-08-31 Thread Dan Minette

- Original Message - 
From: Gautam Mukunda [EMAIL PROTECTED]
To: Killer Bs Discussion [EMAIL PROTECTED]
Sent: Tuesday, August 31, 2004 1:11 PM
Subject: Re: Privately funded medical research is evil,why it must be
eradicated


 --- Alberto Monteiro [EMAIL PROTECTED] wrote:
  ... I claim that has _already_ been oriented to them
  in the past 50 or so years, where _no_ significant
  disease has found a final _cure_.
 
  Alberto Monteiro

 The problem, Alberto, is that the antibiotics were
 discovered a little bit before that.  Anti-viral
 research is hard.  No one has ever succeeded at that.

Yes and no.  It is possible to come up with vacines to prevent viral
diseases.  The polio vacine is a great example of this.  When the virus
mutates on a regular basis, (e.g. the flu), the vacine is not as effective
against the mutated form.  The greater the mutation, the less immuity that
a previous exposure/vacine gives.

We now have a hepititus B vacine (IIRC), as well as German measles,
measles, and mumps.  They have all been developed during the last 30-40
years.

 Also, btw, you're completely ignoring the enormous
 progress that has been made against (for example)
 cancer.  A generation ago (I don't remember the exact
 numbers, but these will be roughly correct) the
 majority of pediatric cancer patients died.  Now it's
 under a quarter.  Almost all of that improvement is
 due to the work of the pharmaceutical companies, and
 that's just a beginning.


And there are subsets of pediatric cancer that have even higher sucess
rates.  With cancer, its never called a cure, but remissions that last 20
years and counting are a first order approximation to a cure.

Dan M.


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Re: Privately funded medical research is evil, why it must be eradicated

2004-08-31 Thread Gautam Mukunda
--- Dan Minette [EMAIL PROTECTED] wrote:
 Yes and no.  It is possible to come up with vacines
 to prevent viral
 diseases.  The polio vacine is a great example of
 this.  When the virus
 mutates on a regular basis, (e.g. the flu), the
 vacine is not as effective
 against the mutated form.  The greater the mutation,
 the less immuity that
 a previous exposure/vacine gives.
 
 We now have a hepititus B vacine (IIRC), as well as
 German measles,
 measles, and mumps.  They have all been developed
 during the last 30-40
 years.

Sorry - by anti-viral research I meant literally,
research on anti-virals - drugs that can be used to
treat viral infections, not just vaccines.  There has,
in fact, been considerable work done on vaccines in
the last 50 years.

Here is (_again_) an area where the industry gets
screwed, though.  When a vaccine is put on the market,
either or both of two things usually happens:
1. The government becomes the sole purchaser,
exercises monopsony power, and sets a price so low
that the vaccine never pays off the investment to
develop it
2. The pharmaco that puts out the vaccine gets sued on
specious grounds, and ends up having to pay through
the nose

I don't see, though, how either of these two things
are the industry's _fault_.  If anything, those
pharmacos that do still do vaccine research (and some
do) should be praised (although not, probably, by
their shareholders) for being willing to continue on
with this sort of research in this environment.

=
Gautam Mukunda
[EMAIL PROTECTED]
Freedom is not free
http://www.mukunda.blogspot.com




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RE: JDG-Type ...Fool, this is out-of-line.

2004-08-31 Thread Horn, John
 Behalf Of Andrew Paul
  
   Let's NOT have a flamewar with the TITLES of our posts?
  
  Seconded.
 
 Thirded.

Fourthed.  Fourth-a-ded.  Four-a-th.  Uh, me too!

 - jmh
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RE: JDG-Type ...Fool, this is out-of-line.

2004-08-31 Thread Gautam Mukunda
--- Horn, John [EMAIL PROTECTED] wrote:

  Behalf Of Andrew Paul
   
Let's NOT have a flamewar with the TITLES of
 our posts?
   
   Seconded.
  
  Thirded.
 
 Fourthed.  Fourth-a-ded.  Four-a-th.  Uh, me too!
 
  - jmh

It is, of course, out of line...but the Fool has been
similarly out of line for years.  What makes this
particular egregious insult any worse from ones in the
past, if I may ask?

=
Gautam Mukunda
[EMAIL PROTECTED]
Freedom is not free
http://www.mukunda.blogspot.com




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Re: JDG-Type ...Fool, this is out-of-line.

2004-08-31 Thread Dan Minette

- Original Message - 
From: Gautam Mukunda [EMAIL PROTECTED]
To: Killer Bs Discussion [EMAIL PROTECTED]
Sent: Tuesday, August 31, 2004 3:32 PM
Subject: RE: JDG-Type ...Fool, this is out-of-line.


 --- Horn, John [EMAIL PROTECTED] wrote:
 
   Behalf Of Andrew Paul

 Let's NOT have a flamewar with the TITLES of
  our posts?

Seconded.
   
   Thirded.
  
  Fourthed.  Fourth-a-ded.  Four-a-th.  Uh, me too!
  
   - jmh
 
 It is, of course, out of line...but the Fool has been
 similarly out of line for years.  What makes this
 particular egregious insult any worse from ones in the
 past, if I may ask?

It migrated to the title, I think.  

quote
Let's NOT have a flamewar with the TITLES of our posts?

---David

end quote

Dan M.

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Re: Privately funded medical research is evil, why it must be eradicated

2004-08-31 Thread Alberto Monteiro
Gautam Mukunda wrote:

 ... I claim that has _already_ been oriented to them
 in the past 50 or so years, where _no_ significant
 disease has found a final _cure_.

 The problem, Alberto, is that the antibiotics were
 discovered a little bit before that.  

Yep. And vaccines another 50 years before that. And sterile
surgery another 50. So maybe there's a 50-year-cycle here :-)

 Anti-viral
 research is hard.  No one has ever succeeded at that.

And I have a suspicion as to _why_.

Every other science has progressed geometrically over the past
50 years. If Medicine had advanced the way computers have, we
would have a life expectancy of 500 years [except that once every
42 days our bodies would burn, and we would have to be rebuild
from the clone backup :-)]

 Why, exactly, do you blame the pharma companies for
 not succeeding in doing something that no one has ever
 succeeded in doing?  

I am not blaming them for _not_ doing this. I am blaming
everybody else that allows them to control medical research.

 They have successfully managed to
 cure every bacterial disease - that's a pretty good
 record.

Did they? What about the new superbacterias that resist every
antibiotic?

 Also, btw, you're completely ignoring the enormous
 progress that has been made against (for example)
 cancer.  

No, I am not. But there is no _cure_, just expensive drugs
to turn cancer into a chronical disease.

 A generation ago (I don't remember the exact
 numbers, but these will be roughly correct) the
 majority of pediatric cancer patients died.  Now it's
 under a quarter.  Almost all of that improvement is
 due to the work of the pharmaceutical companies, and
 that's just a beginning.

Who extract huge profits from drugs that keep cancer
patients bound to them _forever_.

 So if your argument is We can't beat cancer with one
 pill, and I blame the pharmacos, well, blame them all
 you want, but unless you want to point out to me the
 huge medical advances that (for example) the Soviet
 Union made I think you've got a pretty difficult
 situation trying to prove that this is because of a
 choice on their part.

Ok, but then it's still 0 x 0 :-)

 As the chief of RD at a very large pharmaco said in
 an interview a couple of weeks ago - This isn't
 rocket science.  This is _much harder_ than rocket
 science.  You can see a rocket.  You know exactly how
 a rocket works.  We don't (for example) understand the
 liver at all well - we barely understand it at all,
 really.  Drug development is harder now because all of
 the low-hanging fruit - the bacterial diseases and the
 easy vaccines, basically - have already been plucked.
 Now the really hard slog is there.  Despite that fact,
 the same pharma companies that you criticize have
 managed to change AIDS from a fatal to chronic disease
 and improve the survival rates for most forms of
 cancer by _multiples_.  Do you think that was _easy_?
 Merck has more Nobel prize winners on staff than most
 universities - they didn't win all of those because
 they do poor work.  They won them because they do
 extraordinary work on exceptionally difficult areas of research.

I don't doubt the difficulty of the problem, and I don't deny that
they deserve merit for those paliative drugs.

But your keen understanding of _Capitalist_ just clarified my
point. Do you think you are so much smarter than any advisor
that has ever counseled the drug companies? Don't you think
any other intelligent consultant could duplicate your reasoning
that it's a bad idea to research a drug that cures disease X
instead of a drug that keeps a X-patient forced _forever_ to buy
drugs that will extend his life?

Capitalism has no compassion :-/

Alberto Monteiro

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Re: JDG-Type ...Fool, this is out-of-line.

2004-08-31 Thread Alberto Monteiro
Gautam Mukunda wrote:

 It is, of course, out of line...but the Fool has been
 similarly out of line for years.  What makes this
 particular egregious insult any worse from ones in the
 past, if I may ask?

Because it's an insult in the subject line. It's like if you
replied to me in the pharmaco thread with Alberto
is a children-eating communist!

Alberto Monteiro

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Re: Privately funded medical research is evil, why it must be eradicated [was: Fascist Censorship Spreads: Vichy Style]

2004-08-31 Thread Erik Reuter
On Tue, Aug 31, 2004 at 10:20:01AM -0700, Gautam Mukunda wrote:

 If, at some point in the future, someone trusts you with a job
 that involves decisions and information that have to be handled
 responsibly, perhaps you will understand where I'm coming from.

You know, Gautam, if you don't keep reminding us we might forget how
important you are and how you have all sorts of contacts and secret
information that you can't share with us.


-- 
Erik Reuter   http://www.erikreuter.net/
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Re: Privately funded medical research is evil, why it must be eradicated

2004-08-31 Thread Russell Chapman
Alberto Monteiro wrote:
Don't you think
any other intelligent consultant could duplicate your reasoning
that it's a bad idea to research a drug that cures disease X
instead of a drug that keeps a X-patient forced _forever_ to buy
drugs that will extend his life?
Capitalism has no compassion :-/
Doesn't that become a pricing issue?
My wife is two-thirds of the way through her chemotherapy, plus a 
radiotherapy treatment yet to come, and then many years of Tamoxifen 
still to come after that.
While the pharmaceutical costs of all this must be high (and therefore 
the return to the drug companies lucrative), I wouldn't hesitate to 
mortgage our house to pay for a cure.

Even on a basic financial cost, the price I would pay for a cure is the 
future value of the next 5 years of Tamoxifen, plus the cost of the 
Neurolastin for the next few months, plus the cost of the Epirubicin, 
Flourouracil and Cyclophosphamide currently being used, plus the cost of 
all the palliatives used to survive the treating drugs. Therefore, at 
that minimum a drug company could reasonably expect to be able to charge 
 that much for its cure drug.

Additionally, the drug company with the cure gets all of my money, 
whereas the maker of each treatment drug gets only the money for their 
component of the treatment package. Again, the return is higher for the 
cure.

On top of that, what premium wouldn't I pay to not have her go through 
the trauma of chemo and the discomfort and inconvenience of 
radiotherapy? Perhaps (depending on the cure) to not have to go through 
the second and third operations she went through, or the reconstructions 
she faces next year? The answer is I would pay anything for a cure drug.

Cheers
Russell C.


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Re: JDG-Type ...Fool, this is out-of-line.

2004-08-31 Thread William T Goodall
On 1 Sep 2004, at 12:20 am, Alberto Monteiro wrote:
Gautam Mukunda wrote:
It is, of course, out of line...but the Fool has been
similarly out of line for years.  What makes this
particular egregious insult any worse from ones in the
past, if I may ask?
Because it's an insult in the subject line. It's like if you
replied to me in the pharmaco thread with Alberto
is a children-eating communist!
You're not a communist!
--
William T Goodall
Mail : [EMAIL PROTECTED]
Web  : http://www.wtgab.demon.co.uk
Blog : http://radio.weblogs.com/0111221/
Mac OS X is a rock-solid system that's beautifully designed. I much 
prefer it to Linux. - Bill Joy.

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Re: Privately funded medical research is evil, why it must be eradicated

2004-08-31 Thread Erik Reuter
On Wed, Sep 01, 2004 at 09:58:39AM +1000, Russell Chapman wrote:

 On top of that, what premium wouldn't I pay to not have her go
 through the trauma of chemo and the discomfort and inconvenience
 of radiotherapy? Perhaps (depending on the cure) to not have to
 go through the second and third operations she went through, or
 the reconstructions she faces next year? The answer is I would pay
 anything for a cure drug.

No. You would pay as much as you had (or could lay your hands on), but
not anything. There is definitely a limit. For most people, that limit
would probably be much lower than for you (the higher the price, the
less the demand). And if insurance pays for it, then everyone pays for
it, and the government(s) would find a way to force a lower price. Or
someone else would find a slight variation and undercut the price of the
original treatment. Or there would be a big black market. Or all of the
above. It is almost surely less profitable to develop a cure rather than
a long treatment.


-- 
Erik Reuter   http://www.erikreuter.net/
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Re: Privately funded medical research is evil, why it must be eradicated

2004-08-31 Thread Russell Chapman
Erik Reuter responded when:
On Wed, Sep 01, 2004 at 09:58:39AM +1000, Russell Chapman wrote:
On top of that, what premium wouldn't I pay to not have her go
through the trauma of chemo and the discomfort and inconvenience
of radiotherapy? Perhaps (depending on the cure) to not have to
go through the second and third operations she went through, or
the reconstructions she faces next year? The answer is I would pay
anything for a cure drug.
No. You would pay as much as you had (or could lay your hands on), but
not anything. There is definitely a limit. For most people, that limit
would probably be much lower than for you (the higher the price, the
less the demand). And if insurance pays for it, then everyone pays for
it, and the government(s) would find a way to force a lower price. Or
someone else would find a slight variation and undercut the price of the
original treatment. Or there would be a big black market. Or all of the
above. It is almost surely less profitable to develop a cure rather than
a long treatment.
But whatever that abritrary amount is that I can lay my hands on, or 
that insurance companies will supply, it will always be a lot higher 
than for the treatment drugs. Especially if it removes all the hospital 
time and surgeon's costs that the patient and/or insurance company pay 
as well.
All the other factors (undercutting/black market etc) apply to the 
treatment drugs as well so aren't as significant when we are talking 
about return on a cure compared to return on a treatment.

Cheers
Russell C.

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Re: The McCain Fizzle

2004-08-31 Thread JDG
At 12:33 PM 8/31/2004 -0400 Bryon Daly wrote:
I don't think so either.  I think despite McCain's loyalty to the
party in campaigning for and endorsing Bush (and rejecting the Kerry
VP offer), he will be remembered by the Republicans far more for his
few small disloyalties like his assorted criticisms of Bush over the
years, his weak Bush endorsement, and words of praise for Kerry.
Given the close race, I think that these small things will be given
exagerated weight, and he will be a major scapegoat if Bush loses.

You missed the biggest one... you have to be pro-life to win the Republican
primaries, and McCain has gained a reputation as being insufficiently
pro-life.

JDG

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RE: JDG-Type ...Fool, this is out-of-line.

2004-08-31 Thread JDG
At 01:32 PM 8/31/2004 -0700 Gautam Mukunda wrote:
Let's NOT have a flamewar with the TITLES of
 our posts?
   
   Seconded.
  
  Thirded.
 
 Fourthed.  Fourth-a-ded.  Four-a-th.  Uh, me too!
 
  - jmh

It is, of course, out of line...but the Fool has been
similarly out of line for years.  What makes this
particular egregious insult any worse from ones in the
past, if I may ask?

Thank you to all those who responded.   The ironic thing, of course, is
that I have long since concluded that The Fool is not interested in serious
conversation and he has been firmly planted in my killfile for a while now.
  So, without this welcome uproar I would never have known that this had
happened.   I am curious as to what a Jeeb-O is?   

Hopefully this will inspire The Fool to act like a member of a community,
let alone a civilization.

JDG


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Re: Fascist Censorship Spreads: Vichy Style

2004-08-31 Thread Warren Ockrassa
On Aug 26, 2004, at 7:18 AM, Alberto Monteiro wrote:
Warren Ockrassa wrote:
So Perestroika and Glasnost and so on, and eventually Communism in
Russia went away (for now!). The same will *probably* happen in China
and North Korea, but I'll say again that it doesn't magically happen.
There must be competition from other societies, if for no other reason
than to get the oppressed thinking in terms of their own rights and
liberties (as being at least as valid as those of the Great Leader).
I think exactly the _opposite_: a totalitarian regime can only survive 
for
a long time if there is an external competition. The external 
competition
is the stabilizing factor that prevents the minions of the Evil 
Overlord
to fight among themselves to become the next Evil Overlord.
Mm, but you could argue that a similar social decay is taking place now 
in the US; we no longer have an Evil Empire to face, so we're slowly 
destroying ourselves, working frantically to hate *someone* and turning 
to the guy next door to do it.

Of course this does not prevent the worst-case-scenario of 1984,
with three competing totalitarian regimes. Could we become this,
with China, the USA and someone else [Europe? The Muslim World?
An Arab-Europe coalition?] turned into totalitarian regimes and
oppressing the world?
Three, or four maybe, sure.
-- WthmO
Warren's Workable Gun Control Plan:
Arm everyone but the wealthy.
--
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AIDS: The Moral Scourge

2004-08-31 Thread The Fool
The RNC Speaker just told the assembly that hiv/AIDS was a Moral
Scourge.


--
[I]t is proper to take alarm at the first experiment on our liberties.
The freemen of America did not wait till usurped power had strengthened
itself by exercise, and entangled the question in precedents. They saw
all the consequences in the principle, and they avoided the consequences
by denying the principle.
— James Madison, Remonstrance Against Religious Assessments (1786).
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Re: The Mercies of The Vatican

2004-08-31 Thread Warren Ockrassa
On Aug 26, 2004, at 1:07 PM, Travis Edmunds wrote:

From: Warren Ockrassa [EMAIL PROTECTED]

Gene space arguments are fine if you're discussing creatures with no 
clear sense of self-awareness or consequences for actions, such as 
bacteria or tobacco company attorneys. Once you install a sense of 
I, things change.
Keep in mind, that a sense of I is limited entirely to the I.
No; it actually predicts you -- by distinguishing oneself from 
others, others must logically spring into existence.

That is, I don't think you can have an I in a vacuum. This means that 
the presence of self-awareness, being almost by definition 
other-awareness as well, changes how an I-conscious being behaves. 
Gene-motivated actions aren't the sole deciding factor any more.

-- WthmO
This email is a work of fiction. Any similarity between its contents 
and any truth, entire or partial, is purely coincidental and should not 
be misconstrued.
--

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Re: The McCain Fizzle

2004-08-31 Thread The Fool
 From: JDG [EMAIL PROTECTED]
 
 At 12:33 PM 8/31/2004 -0400 Bryon Daly wrote:
 I don't think so either.  I think despite McCain's loyalty to the
 party in campaigning for and endorsing Bush (and rejecting the Kerry
 VP offer), he will be remembered by the Republicans far more for his
 few small disloyalties like his assorted criticisms of Bush over the
 years, his weak Bush endorsement, and words of praise for Kerry.
 Given the close race, I think that these small things will be given
 exagerated weight, and he will be a major scapegoat if Bush loses.
 
 You missed the biggest one... you have to be pro-life to win the
Republican
 primaries, and McCain has gained a reputation as being insufficiently
 pro-life.

I might be talked into voting for someone like mccain.  I will never vote
for someone like JDG.

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Re: The Mercies of The Vatican

2004-08-31 Thread Warren Ockrassa
On Aug 26, 2004, at 6:43 PM, [EMAIL PROTECTED] wrote:
In a message dated 8/25/2004 9:31:32 PM Eastern Daylight Time,
[EMAIL PROTECTED] writes:

That's not evolved; the only reason one would have guilt after rape
would be if one believed it to be a bad thing. Guilt is a
socially-created phenomenon.
Ah but here you are wrong. Guilt serves a very useful purpose in social
animals that use recipricol altruism. It is an internal and largely 
unconscious
talleying up of whether one's actions are likley to be viewed as 
reasonable by
other members of the society.
But that underscores my point of view. Assuming social rules change, 
and they do, guilt definitions change as well. Not wanting to be 
outcast from the group is surely older than primates (think small 
huddling rodentlike creatures); the idea of guilt over an action that 
is *socially proscribed* is really an extension of the desire not to be 
outcast. But the action itself is determined by society to be 
acceptable or not, so the presence of guilt (and the degree to which 
it's felt, and the ways in which it is to be ameliorated or addressed) 
are also social phenomena.

Guilt is an internal sense of whether one is
behaving correctly and therefore it is a inhibitor of selfish behavior.
No; it's an inhibitor of behavior that one's peers would find 
objectionable.

-- WthmO
This email is being broadcast with a 5-second delay.
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Re: Privately funded medical research is evil, why it must be eradicated

2004-08-31 Thread Erik Reuter
On Wed, Sep 01, 2004 at 10:52:48AM +1000, Russell Chapman wrote:

 But whatever that abritrary amount is that I can lay my hands on, or
 that insurance companies will supply, it will always be a lot higher
 than for the treatment drugs.

No, in total it will be a lot lower. It is much easier to come up with
$1000 per week than it is to come up with $1,000,000 at once. It is much
easier to get around paying asking price for a single cure than it is
for a drawn-out treatment.

 All the other factors (undercutting/black market etc) apply to the
 treatment drugs as well   

No, I don't think so. Not to the same degree. It is much easier to do it
for a single cure than for a continuing treatment.

-- 
Erik Reuter   http://www.erikreuter.net/
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Re: Fascist Censorship Spreads: Vichy Style

2004-08-31 Thread Warren Ockrassa
On Aug 26, 2004, at 6:40 AM, Gautam Mukunda wrote:
--- Warren Ockrassa [EMAIL PROTECTED] wrote:
I still feel (so far) that, all things being equal
or equivalent
(population, power, etc) at the beginning of a
contest, if you have two
evenly-matched nations, one of which is totalitarian
and the other more
liberty-oriented, the totalitarian system will
ultimately, eventually
collapse. I don't believe totalitarian systems are
flexible, innovative
or robust enough to survive that kind of
competition.
This is an argument first made my Machiavelli in his
Discourses on Livy.  Tocqueville also suggested in
_Democracy in America_, although, oddly enough, he
didn't apply it to the US.  In both cases, though,
they believed that this was something that could
happen only after a democracy had a long time to
develop.
I suppose the question then becomes how long a long time is. And one 
could argue that any government, at inception, is vulnerable; but it's 
probably fair to say that democracies tend to be more vulnerable for a 
longer time initially than, say, a dictatorship or theocracy. (But I 
repeat myself. ;)

The point Dan and I are making, though, is that
historically, things usually aren't equal.
Very true. Which is why a democratic superpower is an interesting 
concept.

There are
lots of highly plausible scenarios you can spin where
the most powerful country in the world is a fascist
dictatorship (Nazi Germany), a totalitarian Communist
dictatorship (the USSR), or any number of other
options.  For example, had the North lost the Civil
War, it's arguable that democratic reform in England
would have been far less successful - certainly,
that's what Gladstone thought, and he ought to have
known.
Well, maybe. IIRC France had already taken up the banner by then as 
well, so possibly that could have been a factor. My European history 
is, however, nowhere near sufficient to let me speculate in anything 
like useful depth.

If any of these things had happened, we
wouldn't even know about this hypothetical advantage
democracies have.  The argument that good
governments win their wars is based on events that
could very easily have gone other ways, suggesting
that such an advantage, if it exists, is so small that
it's hardly sufficient to use to justify the
superiority of liberal governments.
I'm not so sure. Yes, the South was disadvantaged industrially in the 
American Civil War, and that could have just been an accident -- I mean 
if the North had been pro-slavery and the South against it, things 
might have gone quite differently. Of course another thing to consider 
is that agriculture might have been better suited to supporting slavery 
to begin with.

But that's dipping back awfully far to try to counter an argument 
discussing events which are, in truth, historically unprecedented. For 
that reason I;m not entirely certain that looking at the history of 
Greece (example) can tell us much about what we'll have to deal with in 
the next 50 years, nor can it tell us much about the whys and 
wherefores of our current apparent position of success.

It's a little weird, really, almost like trying to divine the present 
moment by scrying the past. Nostradamus would love it.

-- WthmO
I don't need a luxury yacht.
A bare necessity yacht will do just fine, thanks.
--
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Re: The McCain Fizzle

2004-08-31 Thread Robert Seeberger

- Original Message - 
From: The Fool [EMAIL PROTECTED]
To: Killer Bs Discussion [EMAIL PROTECTED]
Sent: Tuesday, August 31, 2004 7:59 PM
Subject: Re: The McCain Fizzle


  From: JDG [EMAIL PROTECTED]
 
  At 12:33 PM 8/31/2004 -0400 Bryon Daly wrote:
  I don't think so either.  I think despite McCain's loyalty to the
  party in campaigning for and endorsing Bush (and rejecting the
Kerry
  VP offer), he will be remembered by the Republicans far more for
his
  few small disloyalties like his assorted criticisms of Bush
over the
  years, his weak Bush endorsement, and words of praise for Kerry.
  Given the close race, I think that these small things will be
given
  exagerated weight, and he will be a major scapegoat if Bush
loses.
 
  You missed the biggest one... you have to be pro-life to win the
 Republican
  primaries, and McCain has gained a reputation as being
insufficiently
  pro-life.

 I might be talked into voting for someone like mccain.  I will never
vote
 for someone like JDG.

Well.I wouldn't vote for John for a federal office either.
But I *would* certainly vote for him in a more local office like Mayor
or City Councilperson.
I disagree with John on several issues, but I know him to be
trustworthy and sincere.

xponent
No Really!!! Maru
rob


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Re: JDG-Type ...Fool, this is out-of-line.

2004-08-31 Thread Medievalbk
 
In a message dated 8/31/2004 6:39:01 PM US Mountain Standard Time, 
[EMAIL PROTECTED] writes:

I am curious as to what a Jeeb-O is?   





Any video footage of a Florida governor that makes him look bad 
and can be put on national network news, replacing a minor news
story, say like a 7.0 earthquake in Japan.
 
There's always more room tor more Jeeb-O.
 
Vilyehm
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Re: Privately funded medical research is evil, why it must be eradicated

2004-08-31 Thread Robert Seeberger

- Original Message - 
From: Erik Reuter [EMAIL PROTECTED]
To: Killer Bs Discussion [EMAIL PROTECTED]
Sent: Tuesday, August 31, 2004 8:11 PM
Subject: Re: Privately funded medical research is evil,why it must be
eradicated


 On Wed, Sep 01, 2004 at 10:52:48AM +1000, Russell Chapman wrote:

  But whatever that abritrary amount is that I can lay my hands on,
or
  that insurance companies will supply, it will always be a lot
higher
  than for the treatment drugs.

 No, in total it will be a lot lower. It is much easier to come up
with
 $1000 per week than it is to come up with $1,000,000 at once. It is
much
 easier to get around paying asking price for a single cure than it
is
 for a drawn-out treatment.

  All the other factors (undercutting/black market etc) apply to the
  treatment drugs as well

 No, I don't think so. Not to the same degree. It is much easier to
do it
 for a single cure than for a continuing treatment.


Erik is right.
Think: vitamins vs. immortality treatments
(Per the claim that vitamins can extend ones life.)

xponent
Exaggerations Maru
rob


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Re: The Mercies of The Vatican

2004-08-31 Thread Alberto Monteiro
Warren Ockrassa wrote:

 Keep in mind, that a sense of I is limited entirely to the I.

 No; it actually predicts you -- by distinguishing oneself from
 others, others must logically spring into existence.

 That is, I don't think you can have an I in a vacuum. This means that
 the presence of self-awareness, being almost by definition
 other-awareness as well, changes how an I-conscious being behaves.
 Gene-motivated actions aren't the sole deciding factor any more.

Experimentally, there is no such thing as an I: take a healthy person,
cut the brain in half, removing all communication between the two
hemispheres, and you end up with _two_ different personalities, each
one of them remembers being the former I. I imagine that if it were
possible to keep cutting with surviving remains we would get other
smaller versions of I.

Alberto Monteiro

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Re: thinking about free will

2004-08-31 Thread Warren Ockrassa
On Aug 27, 2004, at 4:44 PM, Alberto Monteiro wrote:
Erik Reuter wrote:

Free will, pretty well be definition, means that it is possible to
make
Except you don't have a useful definition of free will, as you well
know.
Free Will means that your decisions are taken by a soul.
*Screech of tires*
...would you care to define soul?
A soul means that there is something in you that can't be explained
by physics, chemistry, or biology.
Explained, or simply observed?
 = or =
(Materialist definition) A soul means that the processes that happen
inside a brain are so complex that it's impossible [*] to build any 
machine
that exactly reproduces them.

[*] because such machine would be bigger than the Universe
But then there are people like me who reject *any* concept of soul 
and who don't even use the term because it's far too laden with 
baggage.

I also don't believe the processes in the brain are too complex to be 
reproduced or modeled; that's obviously false, as there are 6 billion 
human examples of brainic models right outside my yard.

It's a pretty grave mistake to take today's technology and, using it, 
try to determine what will be impossible in the next few decades. 
While miniaturization of microchips is probably close to its bottom 
limit now, there are other computer options out there, and we might 
eventually see a biological-mechanical hybrid, an engineered collection 
of neurons that functions like a computer, but organically.

Definitions are evil, why they must be eradicated: then an electron has
a soul, because by QM we can't predict the behaviour of one electron 
:-/
That doesn't say anything except that -- possibly -- QM is incomplete, 
though.

And maybe not even that. I can't predict better than 50% reliability 
how a balanced coin will toss. That doesn't mean the coin is volitional 
*or* ensouled. It means it can occupy one of two states; my assigning 
it a value for each toss -- either before *or* after the flip -- is, on 
some level, arbitrary. (It presupposes consciousness and will, yes, but 
not in the coin.)

-- WthmO
More fun than a bucket of live bait.
But not as much fun as a trailerful of raccoons.
--
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Re: JDG-Type ...Fool, this is out-of-line.

2004-08-31 Thread Nick Arnett
I'd like to put a cap on this thread by adding that Julia and I have a 
agreed that this deserved a formal warning from the list managers, to 
refrain from personal attacks, which we're hereby offering to the Fool.

Often, we do this in public, but given the fact that so many others 
publicly condemned it, I figured we might as well say so in public... 
which also seems reasonable given the fact that the Fool chooses not to 
comply with the list's request that people identify themselves by their 
real names, and thus the only personality affected by such a warning is 
the fictious one.

Nick
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Re: The Mercies of The Vatican

2004-08-31 Thread Warren Ockrassa
On Aug 31, 2004, at 6:47 PM, Alberto Monteiro wrote:
Warren Ockrassa wrote:

Keep in mind, that a sense of I is limited entirely to the I.
No; it actually predicts you -- by distinguishing oneself from
others, others must logically spring into existence.
That is, I don't think you can have an I in a vacuum. This means 
that
the presence of self-awareness, being almost by definition
other-awareness as well, changes how an I-conscious being behaves.
Gene-motivated actions aren't the sole deciding factor any more.

Experimentally, there is no such thing as an I: take a healthy 
person,
cut the brain in half, removing all communication between the two
hemispheres, and you end up with _two_ different personalities, each
one of them remembers being the former I.
I seem to recall something along those lines, yes. Says something 
pretty interesting about the nature of consciousness. Mostly (I think) 
that it's not a constant state; that in order for consciousness to 
exist it must always be changing. Memory appears to give us a sense of 
continuity, but the process itself seems like soap in bathwater: The 
harder you try to get hold of it the faster it squirts away.

I imagine that if it were
possible to keep cutting with surviving remains we would get other
smaller versions of I.
I'm sure you're correct. This is actually one reason I was so intrigued 
by _Kiln People_ -- a sort of energetic resonance being passed into 
clay, and then inloaded (before it had too much time to digress into 
its own consciousness) is an interesting idea. If you haven't read the 
book you might want to. ;)

It's why I don't really buy the idea of someone becoming immortal by 
putting his consciousness into a machine. There'd be immediate 
divergence which would only grow over time; in essence you'd have two 
distinct entities in very short order. (Oh, you could kill the body -- 
but that would end the distinct consciousness in the body. I don't 
think there's one essence allotted to a person, IOW.)

But my point was that in distinguishing oneself from the world, one has 
already defined the existence of a place called the world from which 
one is distinct, and any decisions one takes will have that in the 
account. So purely genetics-delimited behavioral definitions do not 
wash with me, especially where high intellect (primate, cetacian, 
possibly mollusccan) is present.

-- WthmO
There is no such thing as mad vegetable disease.
--
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Re: Privately funded medical research is evil, why it must be eradicated [was: Fascist Censorship Spreads: Vichy Style]

2004-08-31 Thread Gautam Mukunda
--- Erik Reuter [EMAIL PROTECTED] wrote:
 You know, Gautam, if you don't keep reminding us we
 might forget how
 important you are and how you have all sorts of
 contacts and secret
 information that you can't share with us.
 
 Erik Reuter   http://www.erikreuter.net/

You know, Erik, if you didn't keep reminding us we
might forget what a jackass you are.  Let me try to be
more clear.  There are certain things I can't comment
on.  Even commenting on publicly available information
can involve me needing to consult a lawyer on
potential securities violations.  Since I'm not an
expert on that field and I don't feel any desire to do
that, I don't, and can't, comment on anything
involving the financials of any pharmaceutical
company, or the industry in general.  I was trying to
courteously say that to Dan, so that he would not
carry that part of the discussion further.  Being a
considerate guy, he understood that.  Since you
aren't, you didn't.  I _can_ talk about general
principles on non-financial issues which is, in fact,
what I've done.  Now is it clear?  My ego's okay, and
of all the ways I can think of to boost it, showing
off in front of you has got to be dead last on the list.

=
Gautam Mukunda
[EMAIL PROTECTED]
Freedom is not free
http://www.mukunda.blogspot.com



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US wounded total in Iraq approaching 7,000

2004-08-31 Thread Robert G. Seeberger
http://www.boston.com/dailynews/244/wash/US_wounded_total_in_Iraq_approP.shtml



The number of American troops wounded in Iraq since the U.S.-led
invasion in March 2003 is approaching 7,000, according to figures
published Tuesday by the Pentagon. The death toll for U.S. military
personnel is 975, plus three Defense Department civilians.
The wounded total has approximately doubled since mid-April, when
casualties and deaths mounted rapidly as the insurgency intensified.
The death toll over that period has grown by about 300.

The Pentagon, which generally updates its casualty count each week,
said the number of wounded stands at 6,916, up 226 from a week
earlier. In the two months since the United States handed over
political sovereignty to an interim Iraq government, the wounded total
has grown by about 1,500.

The vast majority of casualties have been Marines and Army soldiers,
although the Pentagon announced on Tuesday the 13th member of the Air
Force to die in Iraq. Airman 1st Class Carl L. Anderson Jr., 21, of
Georgetown, S.C., was killed by a roadside bomb on Sunday near the
northern city of Mosul. He was assigned to the 3rd Logistics Readiness
Squadron based at Elmendorf Air Force Base, Alaska.



xponent

Not Good News Maru

rob


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Re: JDG-Type ...Fool, this is out-of-line.

2004-08-31 Thread Nick Arnett
Nick Arnett wrote:

Often, we do this in public
I meant private, of course...
Had a sleep study a few weeks ago, which showed that I have severe sleep 
apnea, with 42 events (not breathing for at least 10 seconds) a hour. 
This will now be my excuse for any mistakes I may make... ;-)

Nick
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Re: JDG-Type ...Fool, this is out-of-line.

2004-08-31 Thread Warren Ockrassa
On Aug 31, 2004, at 7:53 PM, Nick Arnett wrote:
Had a sleep study a few weeks ago, which showed that I have severe 
sleep apnea, with 42 events (not breathing for at least 10 seconds) a 
hour. This will now be my excuse for any mistakes I may make... ;-)
Ah. Apnea subverts your free will!
-- WthmO
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Re: Privately funded medical research is evil, why it must be eradicated

2004-08-31 Thread Gautam Mukunda
--- Alberto Monteiro [EMAIL PROTECTED] wrote:
 Gautam Mukunda wrote:
 And I have a suspicion as to _why_.
 
 Every other science has progressed geometrically
 over the past
 50 years. If Medicine had advanced the way computers
 have, we
 would have a life expectancy of 500 years [except
 that once every
 42 days our bodies would burn, and we would have to
 be rebuild
 from the clone backup :-)]

I was about to make that joke...

First, I don't think every other science _has_
progressed geometrically over the past 50 years.  I'm
not sure that theoretical physics, for example, is all
that far advanced today over where it was in 1960, say
- Dan M. can confirm or deny that statement.

But the reason for that is because biology doesn't
have the theoretical foundations that physics and
chemistry do.  It doesn't have anything to do with the
pharmacos, it's just that this stuff is harder.  We
don't have a theoretical model of any high degree of
usefulness for the brain or the liver, for example. 
We still don't understand how proteins interact.  We
only sequenced the human genome a few years ago, and
we've barely begun figuring out what proteins are
expressed by it, much less how those proteins will
interact with each other.  That puts biology in about
the place physics was...before Newton.  So _of course_
medical science hasn't advanced geometrically yet.  

 I am not blaming them for _not_ doing this. I am
 blaming
 everybody else that allows them to control medical
 research.

But they don't.  They're pretty good at it, but I
doubt that even half of the US's research spending is
from the pharmacos.  What they do control is
_development_, but they control it because they're the
only people who are any good at it.  Medical research
is still heavily the province of governments and
universities, so if we're not finding cures, it's
because _they_ haven't found them.

 Did they? What about the new superbacterias that
 resist every
 antibiotic?

What about them?  There are almost no cases of such
bacteria actually doing much outside the laboratory. 
As it is, we got 50 years of virtual freedom from
bacterial diseases, which was pretty good, and we can
still knock them back much more often than 999 times
out of 1000.  The reason that those superbacteria
aren't killing many people yet is, again, because of
the fecundity of the pharmacos, developing not just
one antibiotic (penicillin), but everything from
amoxicillin to cipro, so we have many different ways
to attack a bug.  Not enough, and we need to develop
more, but the ones we have are because of private
industry efforts.

 No, I am not. But there is no _cure_, just expensive
 drugs
 to turn cancer into a chronical disease.

Alberto, I don't understand what you mean by this. 
One of my aunt's had breast cancer a few years ago -
she had surgery, took chemo for a while, and now she's
not.  It's past the five year point, so statistically
her likelihood of a recurrence is (IIRC) about the
same as that for a person who has never had cancer. 
She's not taking any drugs right now.  If that's not a
cure, what is?  Cancer isn't a bacteria, we can't kill
it with a single pill.  It's hard to do.  What's
amazing is how far we've come.


 Who extract huge profits from drugs that keep cancer
 patients bound to them _forever_.

Except they don't.  To pick an example, one of my best
friends in high school had pediatric cancer as an
infact - something in his eye, I think.  He wasn't on
any drugs.  He had been cured, for all practical
purposes?

Now, if a pharmaco could create a drug that could turn
every cancer into a chronic condition - what a
blessing that would be!  If only we were somehow able
to do that.  But we can't.  The record so far is
pretty good, though.  Not good enough, but it gets
better every day.  I would not be stunned to see most
cancers treated exactly that way - turned into chronic
conditions - in my lifetime.  I _expect_ to see heart
disease treated that way in my lifetime (if the
results from the Phase II clinical trials on Pfizer's
HDL enhancing drug end up being as good as some people
hope, that result might actually be in sight.)

 Ok, but then it's still 0 x 0 :-)

Yeah, but the record of people trying to run a 2
minute mile is also pretty bad.  We don't tell runners
to stop running because of it, or call them
incompetent for failing to do it.

 Do you think you are so much smarter than any
 advisor
 that has ever counseled the drug companies? Don't
 you think
 any other intelligent consultant could duplicate
 your reasoning
 that it's a bad idea to research a drug that cures
 disease X
 instead of a drug that keeps a X-patient forced
 _forever_ to buy
 drugs that will extend his life?

I was a very average consultant, so I'm sure plenty of
other consultants have made this calculation.  Here's
the thing, though.  If pharmaco A has a drug that
converts a life-threatening condition into a chronic
one...then pharmacos B, C, D, E, and F have an
incentive to 

Re: The McCain Fizzle

2004-08-31 Thread Bryon Daly
On Tue, 31 Aug 2004 20:44:26 -0400, JDG [EMAIL PROTECTED] wrote:
 At 12:33 PM 8/31/2004 -0400 Bryon Daly wrote:
 I don't think so either.  I think despite McCain's loyalty to the
 party in campaigning for and endorsing Bush (and rejecting the Kerry
 VP offer), he will be remembered by the Republicans far more for his
 few small disloyalties like his assorted criticisms of Bush over the
 years, his weak Bush endorsement, and words of praise for Kerry.
 Given the close race, I think that these small things will be given
 exagerated weight, and he will be a major scapegoat if Bush loses.
 
 You missed the biggest one... you have to be pro-life to win the Republican
 primaries, and McCain has gained a reputation as being insufficiently
 pro-life.

Really?  I had thought one of the serious sticking points that kept him from 
taking the Kerry VP spot was his pro-life position.

If not the pres nomination itself, do you think McCain has a chance to get a 
Republican VP offer?
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Re: The McCain Fizzle

2004-08-31 Thread JDG
At 11:11 PM 8/31/2004 -0400 Bryon Daly wrote:
On Tue, 31 Aug 2004 20:44:26 -0400, JDG [EMAIL PROTECTED] wrote:
 At 12:33 PM 8/31/2004 -0400 Bryon Daly wrote:
 I don't think so either.  I think despite McCain's loyalty to the
 party in campaigning for and endorsing Bush (and rejecting the Kerry
 VP offer), he will be remembered by the Republicans far more for his
 few small disloyalties like his assorted criticisms of Bush over the
 years, his weak Bush endorsement, and words of praise for Kerry.
 Given the close race, I think that these small things will be given
 exagerated weight, and he will be a major scapegoat if Bush loses.
 
 You missed the biggest one... you have to be pro-life to win the Republican
 primaries, and McCain has gained a reputation as being insufficiently
 pro-life.

Really?  I had thought one of the serious sticking points that kept him from 
taking the Kerry VP spot was his pro-life position.

True also.   McCain has managed to strike a middle-of-the-road position on
abortion that ends up pleasing noone. 

At the core of it is that while McCain has generally cast mostly pro-life
votes, he has never appeared to speak from the heart about the pro-life
issue, and most critically of all, has said that he would consider
appointing justices who actually believe that Roe vs. Wade was a decent
piece of jurisprudence.

If not the pres nomination itself, do you think McCain has a chance to get a 
Republican VP offer?

First, I think that McCain's age is such that he probably would not accept
the VP slot.   The VP slot is generally seen these days as primarily a
ticket to the nomination in 8 years.   McCain isn't sure he wants to run
for President in 2008, let alone in 2016.

Secondly, McCain was widely mooted as a potential VP candidate in 2000, and
the pro-life faction of the Republican Party made it abundantly clear that
they would be very displeased to have someone whom they viewed as
insufficiently pro-life only a heartbeat away from the Presidency, and the
heir apparent for 2008.   Moreover, Bush himself did not exactly have
strong pro-life bona fides in 2000, and thus needed to shore up support
from the pro-life faction of the Republican base with a pro-life running
mate.The nominee in 2008 could easily be in a similar predicament.

JDG

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Re: The McCain Fizzle

2004-08-31 Thread Warren Ockrassa
On Aug 31, 2004, at 8:11 PM, Bryon Daly wrote:
If not the pres nomination itself, do you think McCain has a chance to 
get a
Republican VP offer?
One can only wish. I'm certainly not Republican but I would definitely 
have voted for him in 2000, had I had an opportunity. (I voted for 
Nader, but not in a state where it mattered anyway. Which might be all 
50! ;)

I don't see it happening. He's stumping for Dub now but I'd be looking 
more closely at Giuliani shooting for the chair in '04. If that were to 
happen McCain *might* get the veep nod but I still wouldn't count on 
it. The Repubs have swung so far into religion lately that I can't 
imagine them being very tolerant of any deviation from their 
rapidly-narrowing definition of what's acceptable.

It's unfortunate. Lincoln was an unbelievably progressive president. To 
hear him mentioned in the same breath with Reagan -- and without a 
trace of irony -- set my teeth on edge. The US's agrarian areas are 
(IMO) being a little too heavily represented in government lately -- by 
which I mean that apparent policy does not seem to align with what the 
true majority would favor -- and had we had a demographic like this one 
in the 1850s, the South might not have needed to secede to keep its 
bigotries intact.

-- WthmO
George W. Bush:
Putting the 'dense' in presidency since 2001.
--
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Re: The Mercies of The Vatican

2004-08-31 Thread Julia Randolph
On Tue, 31 Aug 2004 19:14:20 -0700, Warren Ockrassa
[EMAIL PROTECTED] wrote:
 On Aug 31, 2004, at 6:47 PM, Alberto Monteiro wrote:
 
  I imagine that if it were
  possible to keep cutting with surviving remains we would get other
  smaller versions of I.
 
 I'm sure you're correct. This is actually one reason I was so intrigued
 by _Kiln People_ -- a sort of energetic resonance being passed into
 clay, and then inloaded (before it had too much time to digress into
 its own consciousness) is an interesting idea. If you haven't read the
 book you might want to. ;)
 
 It's why I don't really buy the idea of someone becoming immortal by
 putting his consciousness into a machine. There'd be immediate
 divergence which would only grow over time; in essence you'd have two
 distinct entities in very short order. (Oh, you could kill the body --
 but that would end the distinct consciousness in the body. I don't
 think there's one essence allotted to a person, IOW.)

Poul Anderson explored this some in his series beginning with _Harvest
the Stars_.  I recommend it.  (Not just for that, but for other
divergence issues.)

 Julia
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The Shrub Hamster...

2004-08-31 Thread The Fool
Didn't make it.

Proving yet again, Stupidity is genetic.

--
Never interrupt your enemy when he is making a mistake.
- Napoleon Bonaparte
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Re: Privately funded medical research is evil, why it must be eradicated [was: Fascist Censorship Spreads: Vichy Style]

2004-08-31 Thread Dan Minette

- Original Message - 
From: Erik Reuter [EMAIL PROTECTED]
To: Killer Bs Discussion [EMAIL PROTECTED]
Sent: Tuesday, August 31, 2004 6:46 PM
Subject: Re: Privately funded medical research is evil,why it must be
eradicated [was: Fascist Censorship Spreads: Vichy Style]


 On Tue, Aug 31, 2004 at 10:20:01AM -0700, Gautam Mukunda wrote:

  If, at some point in the future, someone trusts you with a job
  that involves decisions and information that have to be handled
  responsibly, perhaps you will understand where I'm coming from.

 You know, Gautam, if you don't keep reminding us we might forget how
 important you are and how you have all sorts of contacts and secret
 information that you can't share with us.

ROTFLMAO.  Erik, I really appreciate the work you do in research for this
group, but on this subject you are speaking from ignorance.  Gautam and I
are friends.  We share our personal triumphs and tragedies.  Knowing what I
know about him, a reasonable person would categorize his self-description
on the list as rather modest.  Indeed, his restraint verges on amazing from
time to time...particularly when he could come back with a rather stunning
response.

BTW, I got why he couldn't talk even about common knowledge from the
beginning.  At Teleco, we knew when our VPs knew something because they
would stop talking about subjects that they talked about before.  We knew
what was going on, and respected them for it.

Dan M.


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Re: US wounded total in Iraq approaching 7,000

2004-08-31 Thread Julia Thompson
Robert G. Seeberger wrote:
 
 http://www.boston.com/dailynews/244/wash/US_wounded_total_in_Iraq_approP.shtml
 
 The number of American troops wounded in Iraq since the U.S.-led
 invasion in March 2003 is approaching 7,000, according to figures
 published Tuesday by the Pentagon. The death toll for U.S. military
 personnel is 975, plus three Defense Department civilians.
 The wounded total has approximately doubled since mid-April, when
 casualties and deaths mounted rapidly as the insurgency intensified.
 The death toll over that period has grown by about 300.

rest snipped

The death toll for soldiers from Fort Hood just hit 100:

http://www.statesman.com/news/content/auto/epaper/editions/tuesday/news_144332e607a0d0c400b9.html

(this link will be good through Monday of next week)

Julia
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Re: JDG-Type ...Fool, this is out-of-line.

2004-08-31 Thread Julia Thompson
Nick Arnett wrote:
 
 Nick Arnett wrote:
 
  Often, we do this in public
 
 I meant private, of course...
 
 Had a sleep study a few weeks ago, which showed that I have severe sleep
 apnea, with 42 events (not breathing for at least 10 seconds) a hour.
 This will now be my excuse for any mistakes I may make... ;-)

Will you be undergoing treatment?  That might help out on the mistake
front after awhile.  ;)  (And improve your health in general, in all
likelihood)

Julia

Good Sleep Maru
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Re: The McCain Fizzle

2004-08-31 Thread Julia Thompson
JDG wrote:

 At the core of it is that while McCain has generally cast mostly pro-life
 votes, he has never appeared to speak from the heart about the pro-life
 issue, and most critically of all, has said that he would consider
 appointing justices who actually believe that Roe vs. Wade was a decent
 piece of jurisprudence.

Dang.

I don't believe that Roe v. Wade was decent jurisprudence, not on
abortion grounds, but because it was legislation handed down by the
judicial branch.

Maybe I'm too hung up on the Constitution, but when I read that decision
in the light of what the Constitution says the powers of the judiciary
are, and compare it to other famous Supreme Court decisions, it just
reads *wrong*.

Julia
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Re: Privately funded medical research is evil, why it must be eradicated [was: Fascist Censorship Spreads: Vichy Style]

2004-08-31 Thread Doug Pensinger
Dan wrote:
BTW, I got why he couldn't talk even about common knowledge from the
beginning.  At Teleco, we knew when our VPs knew something because they
would stop talking about subjects that they talked about before.  We knew
what was going on, and respected them for it.
When you hold a government clearance you aren't supposed to even discuss 
stuff that is common knowledge because by doing so you may verify or 
discount information that may or may not be correct.  I'm not sure it the 
same in the private sector, but I'm sure the principal holds

--
Doug
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Re: The Mercies of The Vatican

2004-08-31 Thread Doug Pensinger
Warren wrote:
That is, I don't think you can have an I in a vacuum.
In fact, I think your I's pop right out in a vacuum...
--
Doug
headed for the hills
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