[ccp4bb] Postdoc vacancy

2013-09-27 Thread Laura Spagnolo
Dear colleagues,

I would like to draw your attention to a job opening in my laboratory, at the 
University of Edinburgh, to perform electron microscopy studies of CRISPR-Cas 
assemblies. 

The vacancy number is 020349  and can be accessed here: 
https://www.vacancies.ed.ac.uk/pls/corehrrecruit/erq_jobspec_version_4.display_form
Best regards,
Laura


Dr Laura Spagnolo
Institute of Structural Molecular Biology
University of Edinburgh
Room 506, Darwin Building 
King's Buildings Campus
Edinburgh EH9 3JR
United Kingdom
T: +44 (0)131 650 7066 
F: +44 (0)131 650 8650 
http://www.biology.ed.ac.uk/research/institutes/structure/homepage.php?id=lspagnolo
laura.spagn...@ed.ac.uk









The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


Re: [ccp4bb] Postdoc vacancy - new link

2013-09-27 Thread Laura Spagnolo
Hi,

The former link does not seem to be working, please use this:
https://www.vacancies.ed.ac.uk/

Laura



On 27 Sep 2013, at 16:14, Laura Spagnolo laura.spagn...@ed.ac.uk wrote:

 Dear colleagues,
 
 I would like to draw your attention to a job opening in my laboratory, at the 
 University of Edinburgh, to perform electron microscopy studies of CRISPR-Cas 
 assemblies. 
 
 The vacancy number is 020349  and can be accessed here: 
 https://www.vacancies.ed.ac.uk/pls/corehrrecruit/erq_jobspec_version_4.display_form
 Best regards,
 Laura
 
 
 Dr Laura Spagnolo
 Institute of Structural Molecular Biology
 University of Edinburgh
 Room 506, Darwin Building 
 King's Buildings Campus
 Edinburgh EH9 3JR
 United Kingdom
 T: +44 (0)131 650 7066 
 F: +44 (0)131 650 8650 
 http://www.biology.ed.ac.uk/research/institutes/structure/homepage.php?id=lspagnolo
 laura.spagn...@ed.ac.uk
 
 
 
 
 
 
 
 
 
 The University of Edinburgh is a charitable body, registered in
 Scotland, with registration number SC005336.

Laura Spagnolo
ISMB
University of Edinburgh
laura.spagn...@ed.ac.uk

+44 (0)131 6507066



The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


[ccp4bb] PhD opportunity

2013-12-05 Thread Laura Spagnolo
Dear colleagues,

I am currently looking for up to two PhD students to work on proteins involved 
in double strand DNA repair.

Details on the projects can be found here: 
http://www.findaphd.com/search/ProjectDetails.aspx?PJID=48449
http://www.findaphd.com/search/ProjectDetails.aspx?PJID=48456LID=456

The Eastbio project is open to candidates that meet the residency criteria, the 
other project is open to overseas students. Both are competition funded 
projects. Informal enquiries should be addressed to laura.spagn...@ed.ac.uk, 
the application is online:
http://www.ed.ac.uk/schools-departments/biology/postgraduate/pgr/how-to-apply

***The closing date is December 16th***

Laura



Laura Spagnolo
ISMB
University of Edinburgh
laura.spagn...@ed.ac.uk
http://spagnolo.bio.ed.ac.uk/
+44 (0)131 6507066




-- 
The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


[ccp4bb] Postdoctoral position - University of Edinburgh

2012-06-25 Thread Laura Spagnolo
*** DEADLINE JUNE 27TH ***

I would like to draw your attention to a current opening in my laboratory, to 
work on the electron microscopy of CRISPR complexes with a single particle 
approach (see Zhang et al., Mol. Cell 2012).

The project is really quite exciting. We have plenty of great preliminary data, 
the facility is fully equipped and runs smoothly, the scientific environment is 
vibrant, and Edinburgh is a great place to live!

Full details are available here: 
http://www.jobs.ed.ac.uk/vacancies/index.cfm?fuseaction=vacancies.detailvacancy_ref=3015791
Informal enquiries can be sent to my email address: laura.spagn...@ed.ac.uk

Laura




Dr Laura Spagnolo
Institute of Structural Molecular Biology
University of Edinburgh
Room 506, Darwin Building 
King's Buildings Campus
Edinburgh EH9 3JR
United Kingdom
T: +44 (0)131 650 7066 
F: +44 (0)131 650 8650 
http://www.biology.ed.ac.uk/research/institutes/structure/homepage.php?id=lspagnolo
laura.spagn...@ed.ac.uk









The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


[ccp4bb] Postdoc vacancy in the Boettcher lab - Edinburgh

2012-10-29 Thread Laura Spagnolo
Dear Colleagues, 

I am forwarding this message from Bettina Boettcher.
Please get in touch with her if you have any queries about the opening.

Best regards,
Laura



I have a PostDoc position in my lab at the University of Edinburgh. I am 
looking for a good biochemist with a keen interest to work on the structure 
determination of the Ccr4Not complex. 
A detailed job description can be found at: 
https://www.vacancies.ed.ac.uk 
the vacancy ref is:  005386 (please include leading zeros) 

The deadline for applications is 26.11.2012 
Interviews will be during the first week of December. The anticipated start 
date for the position is not later than 16.1.2013. 

Best regards, 

Bettina Boettcher
The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


Re: [ccp4bb] OT: Has anyone experienced problems with Apple laptop battery expansion?

2012-11-18 Thread Laura Spagnolo
Dear Bill,

Yes, the same happened a year ago or so to me, with a 17 inch MacBookPro bought 
in 2008.
The Apple store in Glasgow replaced it for free within roughly one week, and 
the laptop works well. 

I agree that this is really dangerous, I wonder if it could also cause the leak 
of material from inside (mine exposed some really ugly brown stuff).
Laura


On Nov 18, 2012, at 12:28 AM, William G. Scott wrote:

 Hi folks:
 
 I'm trying to get a sense for how frequently this sort of thing occurs:
 
 CIMG4451.jpeg
 
 That was a macbook air that served me well for four years, but then 
 self-destructed. (I took it to the Apple store.  They generously offered to 
 repair it for $800 or to sell me a new one, and suggested this was normal if 
 you leave the power cord attached after the battery charges, even while 
 giving a lecture or seminar.)  It strikes me as a bit dangerous.
 
 --Bill Scott
 
 
 
 
 
 William G. Scott
 Professor
 Department of Chemistry and Biochemistry
 and The Center for the Molecular Biology of RNA
 228 Sinsheimer Laboratories
 University of California at Santa Cruz
 Santa Cruz, California 95064
 USA
 
 
 

Dr Laura Spagnolo
Institute of Structural Molecular Biology
University of Edinburgh
Room 506, Darwin Building 
King's Buildings Campus
Edinburgh EH9 3JR
United Kingdom
T: +44 (0)131 650 7066 
F: +44 (0)131 650 8650 
http://www.biology.ed.ac.uk/research/institutes/structure/homepage.php?id=lspagnolo
laura.spagn...@ed.ac.uk









-- 
The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


[ccp4bb] PhD studentship

2012-11-23 Thread Laura Spagnolo
Dear Colleagues,

I would like to draw the attention of interested students to this opportunity 
to perform a PhD in my laboratory:
http://www.findaphd.com/search/ProjectDetails.aspx?PJID=41839LID=456

The deadline for applications is 18.01.2013.

Best regards,
Laura



Dr Laura Spagnolo
Institute of Structural Molecular Biology
University of Edinburgh
Room 506, Darwin Building 
King's Buildings Campus
Edinburgh EH9 3JR
United Kingdom
T: +44 (0)131 650 7066 
F: +44 (0)131 650 8650 
http://www.biology.ed.ac.uk/research/institutes/structure/homepage.php?id=lspagnolo
laura.spagn...@ed.ac.uk










-- 
The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


Re: [ccp4bb] archival memory?

2012-12-12 Thread Laura Spagnolo
I would definitely go for babylonian clay...



On Dec 12, 2012, at 10:31 PM, Adrian Goldman wrote:

 I say write them out onto acid-free paper: should be good for at least 300 
 years without active management, if there is no fire.  If that doesn't work, 
 I believe babylonian clay tablets have an even longer expected life time…. 
 
 Dale, I must say I am impressed… I gave up after the exabyte to DAT 
 transition, and decided that if I really wanted to get data sets from (my) 
 old projects, it would be easier to regrow the crystals…
 
   Adrian
 
 
 On 13 Dec 2012, at 00:22, Dale Tronrud wrote:
 
  I don't believe there is a solution that does not involve active
 management.  You can't write your data and pick up those media 25
 years later and expect to get your data back -- not without some
 heroic effort involving the construction of your own hardware.
 
  I have data from Brian Matthews' lab going back to the mid-1970's
 and those data started life on 7-track mag tapes.  I've moved them
 from there to 9-track 1600 bpi tapes, to 9-track 6250 bpi tapes, to
 just about every density of Exabyte tape, to DVD, and most recently
 to external magnetic hard drives (each with USB, Firewire, and eSATA
 interfaces).  The hard drives are about five years old and so far
 are holding up.  Last time I checked I could still read the 10 year
 old DVD's.  I'm having real trouble reading Exabyte tapes.
 
  Write your data to some medium that you expect to last for at least
 five years but anticipate that you will then have to move them to
 something else.
 
  Instead of spending time working on the 100 year solution you should
 spend your time annotating your data so that someone other than you
 can figure out what it is.  Lack of annotation and editing is the
 biggest problem with old data.
 
 Dale Tronrud
 
 P.S. If someone needs the intensities for heavy atom derivatives of
 Thermolysin written in VENUS format, I'm your man.
 
 
 
 On 12/12/2012 1:57 PM, Richard Gillilan wrote:
 Better option? Certainly not TAPE or electromechanical disk drive. CD's and 
 DVD's don't last nearly that long and James Holton has pointed out.
 
 I suppose there might be a cloud solution where you rely upon data just 
 floating around out there in cyberspace with a life of its own.
 
 Richard
 
 On Dec 12, 2012, at 4:41 PM, Dale Tronrud wrote:
 
 
  Good luck on your search in 100 years for a computer with a
 USB port.  You will also need software that can read a FAT32
 file system.
 
 Dale Glad I didn't buy a lot of disk drives with Firewire Tronrud
 
 On 12/12/2012 1:02 PM, Richard Gillilan wrote:
 SanDisk advertises a Memory Vault disk for archival storage of photos 
 that they claim will last 100 years.
 
 (note: they do have a scheme for estimating lifetime of the memory, 
 Arrhenius Equation ... interesting. Check it out: 
 www.sandisk.com/products/usb/memory-vault/ and click the Chronolock tab.).
 
 Has anyone here looked into this or seen similar products?
 
 Richard Gillilan
 MacCHESS
 
 

Dr Laura Spagnolo
Institute of Structural Molecular Biology
University of Edinburgh
Room 506, Darwin Building 
King's Buildings Campus
Edinburgh EH9 3JR
United Kingdom
T: +44 (0)131 650 7066 
F: +44 (0)131 650 8650 
http://www.biology.ed.ac.uk/research/institutes/structure/homepage.php?id=lspagnolo
laura.spagn...@ed.ac.uk










-- 
The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


[ccp4bb] Postdoctoral position in Edinburgh

2008-12-17 Thread Laura Spagnolo

I would like to draw your attention to the following opening:

Vacancy Reference 3010245

Applications are invited for a Post-doctoral position funded by Cancer  
Research UK, to work on structure/function studies of the NMD  
machinery in Dr Laura Spagnolo's group. Applicants must hold a PhD in  
a biological science. Innovative thinking, strong motivation and  
experience in molecular biology, protein expression and purification  
are essential. Previous experience in crystallisation and X-ray  
crystallography and/or electron microscopy coupled to single particle  
analysis would be considered an advantage.


Informal enquiries at the address lspag...@staffmail.ed.ac.uk are  
welcome. Applications at web address:  
http://www.jobs.ed.ac.uk/vacancies/index.cfm?fuseaction=vacancies.detailvacancy_ref=3010245


Best regards,
Laura




--
Dr Laura Spagnolo
Institute of Structural Molecular Biology
Room 702/705, Darwin Building
King's Buildings
Mayfield Road
University of Edinburgh
Edinburgh EH9 3JR
United Kingdom
Mobile: (0)7793 018 625

From 05/01/2009:
T: +44 (0)131 650 7066
F: +44 (0)131 650 8650



--
The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


[ccp4bb] PhD studentship in Edinburgh

2009-02-25 Thread Laura Spagnolo
I am currently looking for a PhD student to work on structure/function  
studies of high-pressure adaptation by X-ray crystallography and  
electron microscopy coupled to single particle analysis. The research  
work will be carried out at the School of Biological Sciences (SBS)  
and at the Centre for Science at Extreme Conditions (CSEC) in  
Edinburgh. State-of-the art equipment for protein expression,  
purification and characterization and for high-pressure studies is  
available. Excellent X-ray crystallography facilities are also in  
place. The SBS has a strong interest in furthering its current  
electron microscopy resources.
Funding would be available for UK nationals or EU nationals with at  
least 3 years permanent residence in the UK.
Please contact Dr Laura Spagnolo (lspag...@staffmail.ed.ac.uk) for  
informal enquiries.

Best regards,
Laura


--
Dr Laura Spagnolo
Institute of Structural Molecular Biology
Room 702/705, Darwin Building
King's Buildings
Mayfield Road
University of Edinburgh
Edinburgh EH9 3JR
United Kingdom
T: +44 (0)131 650 7066
F: +44 (0)131 650 8650




--
The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


[ccp4bb] PhD studentship - Edinburgh, UK

2010-06-10 Thread Laura Spagnolo
A PhD studentship is available immediately in my laboratory at the  
University of Edinburgh.
Our studies focus on structural and biochemical studies of  
macromolecular complexes involved in the maintenance of genome  
stability. For more details, please refer to our website:

http://www.biology.ed.ac.uk/research/institutes/structure/homepage.php?id=lspagnolo

Informal enquiries are welcome. Interested candidates should email a  
CV and names of two referees to laura.spagn...@ed.ac.uk


Eligibility is restricted to UK citizens or EU citizens with 3 years  
residence in the UK.




--
Dr Laura Spagnolo
University of Edinburgh
Institute of Structural Molecular Biology
King's Buildings Campus
Darwin Building, Room 506
Mayfield Road
Edinburgh EH9 3JR
United Kingdom
T: +44 (0)131 650 7066
F: +44 (0)131 650 8650
http://www.biology.ed.ac.uk/research/institutes/structure/homepage.php?
id=lspagnolo



--
The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


[ccp4bb] PhD student recruitment

2014-11-17 Thread Laura Spagnolo
Hi,

I am currently looking to recruit a PhD student to work in my laboratory at the 
University of Edinburgh.
Several projects are available, in the general area of the 
biochemistry/structural biology of protein/nucleic acid complexes.
Depending on the scheme you are eligible to apply for, there is a deadline for 
application of 16.12.2014 or a deadline in early January 2015.

If you are interested in discussing this further, please send an informal 
enquiry to my email address: laura.spagn...@ed.ac.uk

Best regards,
Laura


Dr Laura Spagnolo
Institute of Structural Molecular Biology
University of Edinburgh
Room 506, Darwin Building 
King's Buildings Campus
Edinburgh EH9 3JR
United Kingdom
T: +44 (0)131 650 7066 
F: +44 (0)131 650 8650 
http://www.biology.ed.ac.uk/research/institutes/structure/homepage.php?id=lspagnolo
laura.spagn...@ed.ac.uk










-- 
The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


[ccp4bb] Fully funded PhD studentship (UK fees)

2015-04-01 Thread Laura Spagnolo
A fully funded PhD studentship is available jointly between Dr Laura Spagnolo 
at the University of Edinburgh and Dr Daniel Myatt at the ISIS UK neutron 
source, to work on protein/nucleic acid complexes involved in genome regulation.

 

The student will have an opportunity to receive training in electron 
microscopy, small angle scattering, biochemical and biophysical 
characterization, with access to state of the art facilities at the University 
of Edinburgh and at the Rutherford Appleton Laboratories (near Oxford), and 
will contribute to advancing our knowledge of an important, recently discovered 
biological mechanism.

 

Please contact Dr Spagnolo (laura.spagn...@ed.ac.uk 
mailto:laura.spagn...@ed.ac.uk) for enquiries on the project and on how to 
apply.

 

Funding is in place for 4 years, covering UK fees.



Dr Laura Spagnolo
Institute of Structural Molecular Biology
University of Edinburgh
Room 506, Darwin Building 
King's Buildings Campus
Edinburgh EH9 3JR
United Kingdom
T: +44 (0)131 650 7066 
F: +44 (0)131 650 8650 
http://www.biology.ed.ac.uk/research/institutes/structure/homepage.php?id=lspagnolo
laura.spagn...@ed.ac.uk









The University of Edinburgh is a charitable body, registered in
Scotland, with registration number SC005336.


Re: [ccp4bb] Fwd: [ccp4bb] Remittance advice - Invitation to edit

2016-12-11 Thread Laura Spagnolo
Isn't this mailing list moderated?
Laura

Sent from my iPhone

On 11 Dec 2016, at 17:48, Bonsor, Daniel 
> wrote:


The Nigerian Prince wants your money.

Get Outlook for Android


From: CCP4 bulletin board > 
on behalf of Anindito Sen 
>
Sent: Sunday, December 11, 2016 12:45:16 PM
To: CCP4BB@JISCMAIL.AC.UK
Subject: [ccp4bb] Fwd: [ccp4bb] Remittance advice - Invitation to edit

Guys

are you all receiving the same??? What on earth is this ?

Andy



Begin forwarded message:

From: Hai-fu Fan >
Subject: [ccp4bb] Remittance advice - Invitation to edit
Date: December 12, 2016 at 2:31:56 AM GMT+9
To: CCP4BB@JISCMAIL.AC.UK
Reply-To: Hai-fu Fan >

Please find attached for your review.
Regards.

Hai-fu Fan



[ccp4bb] EPSRC-funded PhD studentship - Spagnolo laboratory, Glasgow, UK

2018-06-27 Thread Laura Spagnolo
Hi,

I am currently advertising an EPSRC-funded PhD studentship to study 
protein-nucleic acid interactions using single molecule fluorescence approaches.

Please see link n.5:
https://www.gla.ac.uk/colleges/mvls/graduateschool/researchopportunities/fundedresearchopportunities/mvlsepsrcstudentships/#/bridgingsinglemoleculelightandelectronmicroscopy:developmentof“rnacurtains”tovisualizeprotein,bridgingsinglemoleculelightandelectronmicroscopy:developmentof“rnacurtains”tovisualizeprotein/rnainteractions

If you need some informal info, please do not hesitate to get in touch with me 
directly.

Best regards,
Laura



Dr Laura Spagnolo
Reader in Structural Biology
Institute of Molecular, Cell and Systems Biology
University of Glasgow
Room 409, Bower Building
University Avenue
Glasgow G12 8QQ
United Kingdom

Tel. + (0)141 3305133





[University of Glasgow: The Times Scottish University of the Year 2018]



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[ccp4bb] PhD studentship - Glasgow University/Astra Zeneca

2018-03-29 Thread Laura Spagnolo
Dear Colleagues,
Applications are invited for a PhD studentship position funded by the 
BBSRC-CASE scheme in the laboratory of Dr Laura Spagnolo, University of 
Glasgow, in collaboration with Dr Taiana Maia de Oliveira, Astra Zeneca, 
Cambridge. The project involves the cryo-electron microscopy study of large 
protein/nucleic acid complexes involved in the maintenance of genome stability.
Candidates should have a first or upper second class degree in biochemistry, 
cell biology or biological/medical science. The successful candidate will have 
the opportunity to work in both academic and industry setting during their 
studentship. The studentship is available to UK nationals and EU students who 
meet the UK residency requirements.
To apply, please send a CV and cover letter to 
laura.spagn...@glasgow.ac.uk<mailto:laura.spagn...@glasgow.ac.uk>. The closing 
date for applications is April 20th, 2018.
Best regards,
Laura



Dr Laura Spagnolo
Reader in Structural Biology
Institute of Molecular, Cell and Systems Biology
University of Glasgow
Room 409, Bower Building
University Avenue
Glasgow G12 8QQ
United Kingdom

Tel. + (0)141 3305133





[University of Glasgow: The Times Scottish University of the Year 2018]


[ccp4bb] Postdoc opening - DNA integrases

2022-11-14 Thread Laura Spagnolo
Hi,

Just a reminder of the upcoming deadline (Nov 26th) to apply for a postdoctoral 
position  in my group, to work on the structure/function study of serine 
integrases.

now with working link :-)

https://my.corehr.com/pls/uogrecruit/erq_jobspec_version_4.display_form
https://www.jobs.ac.uk/job/CUM478/research-associate

Best wishes,

Laura






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[ccp4bb] Postdoc opening - DNA integrases

2022-11-11 Thread Laura Spagnolo
Dear Colleagues,

I am writing to advertise an opening for a postdoctoral position  in my group, 
to work on the structure/function study of serine integrases.
Further info can be found here: 
https://my.corehr.com/pls/uogrecruit/erq_jobspec_version_4.display_form 
(vacancy number 100388)

The deadline for applications is November 26th, 2022.

Best wishes,

Laura


Dr Laura Spagnolo
School of Molecular Biosciences
University of Glasgow, UK
https://www.gla.ac.uk/schools/molecularbiosciences/staff/lauraspagnolo/




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