Re: [Felvtalk] Need Opinions on Testing new cats for FELV
Hi, Michelle, Your post caught my attention. I would tend to agree with your veterinarian about the one month time for testing. Even for kittens. I have worked with Feline Leukemia cats since 1985 and we currently have around 25-35 at any given time. IN spite of the fact that kittens are more susceptible to FeLV, etc. I do agree that if they come up negative, they probably will remain negative. We have several test cases with adult cats, as has my shelter vet who has her own FeLine Leukemia sanctuary, where adult cats that are negative living with the FeLV cats remain negative all their lives. You'll get as many opinions as there are people, but do what you feel is best for the two kits. If your two month old kittens show no signs of any health symptoms, my feeling would be that they are going to test negative. Good luck with them. I would be interested to learn the ages that your FeLV sanctuary cats lived to be, and what were the illnesses that eventually took their lives. I am always interested in learning more from others with experience. Thanks, Carmen (I know, I'm mostly a lurker here, but I love reading the posts when I get the chance!!) > From: [EMAIL PROTECTED]> To: felvtalk@felineleukemia.org> Date: Fri, 5 Sep 2008 20:51:13 +> Subject: [Felvtalk] Need Opinions on Testing new cats for FELV> > > I have two female cats that I rescued from a shelter in the first week of August (one had a litter of kittens 2 days after I picked them up).I have had them for a month now. They have been in the same room but have had no contact with eachother or the others dishes, litterbox, etc.(they sleep in their own giant dogs crates and have little litter boxes and food and water and everything so it's almost like what you see at shelters) They each get 12 hours in their crate and 12 hours out in the room so they don't stir crazy - when the other one is out the crate is turned so they can't see eachother or have face to face contact. I am unfortunately very familiar with feline leukemia, we had a sanctuary for FELV+ cats and our last one just died last October so I am very cautious and aware of the disease and probably know more than most do about it. Because of this though I think maybe I'm paranoid about it. The kittens are a month old now and really need to have free roam of the room so I was going to get the mom cat and the other girl I have tested so they can cohabitate in the room until they get fixed and to new homes. I have 12 personal cats and don't have any 'free rooms' to let them each have one or I would do that. A rescuer bailed last minute which is how I ended up with two cats. I'm just worried that the incubation period for FELV is 2 months and it's only been one month and I don't know where they came from or what they were exposed to prior to me getting them. I also know FELV in adult cats, usually takes prolonged exposure unless it was transmitted inutero. SO - am I being too paranoid? Should I just get them tested and not worry about it if it comes back neg?My vet said a month should be a fair place to test them at and he's never had a neg come back pos later on> Michelle Brockman > _> Stay up to date on your PC, the Web, and your mobile phone with Windows Live.> http://clk.atdmt.com/MRT/go/msnnkwxp1020093185mrt/direct/01/> ___> Felvtalk mailing list> Felvtalk@felineleukemia.org> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _ Want to do more with Windows Live? Learn “10 hidden secrets” from Jamie. http://windowslive.com/connect/post/jamiethomson.spaces.live.com-Blog-cns!550F681DAD532637!5295.entry?ocid=TXT_TAGLM_WL_domore_092008 ___ Felvtalk mailing list Felvtalk@felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org
[Felvtalk] Need Opinions on Testing new cats for FELV
I have two female cats that I rescued from a shelter in the first week of August (one had a litter of kittens 2 days after I picked them up).I have had them for a month now. They have been in the same room but have had no contact with eachother or the others dishes, litterbox, etc.(they sleep in their own giant dogs crates and have little litter boxes and food and water and everything so it's almost like what you see at shelters) They each get 12 hours in their crate and 12 hours out in the room so they don't stir crazy - when the other one is out the crate is turned so they can't see eachother or have face to face contact. I am unfortunately very familiar with feline leukemia, we had a sanctuary for FELV+ cats and our last one just died last October so I am very cautious and aware of the disease and probably know more than most do about it. Because of this though I think maybe I'm paranoid about it. The kittens are a month old now and really need to have free roam of the room so I was going to get the mom cat and the other girl I have tested so they can cohabitate in the room until they get fixed and to new homes. I have 12 personal cats and don't have any 'free rooms' to let them each have one or I would do that. A rescuer bailed last minute which is how I ended up with two cats. I'm just worried that the incubation period for FELV is 2 months and it's only been one month and I don't know where they came from or what they were exposed to prior to me getting them. I also know FELV in adult cats, usually takes prolonged exposure unless it was transmitted inutero. SO - am I being too paranoid? Should I just get them tested and not worry about it if it comes back neg?My vet said a month should be a fair place to test them at and he's never had a neg come back pos later on Michelle Brockman _ Stay up to date on your PC, the Web, and your mobile phone with Windows Live. http://clk.atdmt.com/MRT/go/msnnkwxp1020093185mrt/direct/01/ ___ Felvtalk mailing list Felvtalk@felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org
Re: [Felvtalk] FeLV diversity
Thank you for posting this information Herbert. It helps explain why this disease progresses so differently in our beloved cats. Sharyl --- On Thu, 9/4/08, hebert ferrarezzi <[EMAIL PROTECTED]> wrote: From: hebert ferrarezzi <[EMAIL PROTECTED]> Subject: [Felvtalk] FeLV diversity To: felvtalk@felineleukemia.org Date: Thursday, September 4, 2008, 8:45 AM I found the following introductory paragraph of an article from The Journal of Virology very interesting (and not excessively technical), to be posted here. It provides some possible explanations to the differences regarding latency period, survival time, associate malignancies and other disease outcomes that we have witnessed, which could be related to different kinds of FeLV viruses recognizable by means of molecular sequence comparisons: "Feline leukemia virus (FeLV) is a naturally occurring gammaretrovirus of the domestic cat. FeLV is endemic in free-roaming urban domestic cats, serological survey of which shows that at least 50% of adult animals have been infected. The disease outcome of natural FeLV infection is variable and rather unpredictable. Among persistently infected animals, the majority succumb to degenerative diseases, including anemia or immunodeficiency; however, a substantial minority develop neoplastic or proliferative diseases, including lymphoma, leukemia, or myeloproliferative disorder. The determinants of disease outcome in natural FeLV infection have not been clearly defined but probably involve a combination of host, viral, and environmental factors. While there is little doubt that the genetic heterogeneity of the outbreeding mammalian host exerts an influence on disease outcome, the genetic heterogeneity of FeLV in nature clearly has an impact as well. Like other natural retrovirus populations, FeLV is not a single genomic species but represents a family of closely related viruses. Four natural subgroups of FeLV (A, B, C, and T) have been described on the basis of sequence differences in the surface glycoprotein (SU) and on receptor interactions required for entry. Subgroup A FeLV (FeLV-A) includes the ecotropic, weakly pathogenic viruses that are horizontally transmitted in nature. Infection with FeLV-A is associated with prolonged, asymptomatic persistent infection that may lead to malignant lymphoma, typically of T-cell origin. For example, infection with FeLV-A/61E in several studies induced thymic lymphoma in some animals after prolonged latency for up to 2 years, but other animals remained healthy for even longer periods of observation. FeLV-A is present in all natural infections and gives rise to the other subgroups by envelope (env) gene mutation, insertion, or recombination events de novo. FeLV-B is a polytropic virus that arises by recombination with endogenous FeLV-related sequences. The disease association of FeLV-B infection remains unclear; however, FeLV-B is unusually common in animals with lymphoid malignancy and thus may be linked to the induction of that disease. FeLV-C is also a polytropic virus that arises by mutation in the SU gene. FeLV-C is strongly associated with aplastic anemia in infected animals. FeLV-T has recently been classified and includes T-cell-tropic cytopathic viruses that cause lymphoid depletion and fatal immunodeficiency disease in infected cats. FeLV-T evolves from FeLV-A by mutation and insertion in the SU gene. The association of particular outcomes with FeLV subgroups as described above suggests that the nature of the virus isolate is the major disease determinant in FeLV infection. In fact, in the case of anemia or immunodeficiency induced by FeLV-C or FeLV-T, the genetic regions responsible for directing disease outcome have been localized to mutations or insertions in the FeLV SU gene. By comparison, the viral determinants of neoplastic disease have not been as clearly defined." Chandhasin et al. full text is available at http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=15827142 Thanks for the attention, Hebert _ Instale a Barra de Ferramentas com Desktop Search e ganhe EMOTICONS para o Messenger! É GRÁTIS! http://www.msn.com.br/emoticonpack ___ Felvtalk mailing list Felvtalk@felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org ___ Felvtalk mailing list Felvtalk@felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org
