Re: [Felvtalk] Gilbert...

[Pam Doore]

I have been a foster failure 4 times.  Once I saw how well the foster's did
with the the other cats and I fell in love, they had to stay :-D.

As far as treating shelter pets, I know that at my shelter there is a set
amount per pet and anything above that comes from a special account which
has been newly set up.  We do not have a vet at our shelter, we have to
take the cats and dogs to the vet clinic and there really is no shelter
discount for medicine or office visits.  I can't make decisions for pets
based on money alone.  My goal is always the quality of life.

I wish you and Gilbert all the best in getting him the right meds to keep
him pain-free :-D.  I love the image of a 15lb kitty snoozing on your chest
:).


~~@~@~@~@~@

*Christ beside me, Christ before me, Christ behind me, Christ within me,
Christ beneath me, Christ above me. — **St. Patrick*


On Sun, Jun 25, 2017 at 5:21 PM,  wrote:

> They do get under our skin and become a necessary to our lives.  I have 3
> 15 pounders who think I am a mattress for them to sleep on.  Thank God they
> take turns.  Does Gilbert like to KNEED a lot?  Homey gets into a trance
> and digs deeply so I have had to explain to doctors what all those little
> red spots are.  Do you have to foster, or can you just adopt so you can
> give pain treatment as you see fit?
> I end up adopting everyone that comes my way.  After just a couple of days
> I could not let them go.
>
>  ROBERT CHAPEL  wrote:
> >
>
> Amani...
> As always... thank you for the advice and all the other references to
> research ( Doxy, Cannabinol) that can be helpful down the road...   In
> the case of Gilbert it is perplexing that they are so withholding re:
> drugs.  Gilbert is a favorite of everyone and no one wants to see him
> hurting  I'll keep making suggestions.  Starting once again to pay
> my own ( larger) medical contributions under medicare I cannot afford to
> be taking him to vets on my own ( as well as it being a potential
> problem if I do because he is ( technically) the shelters " property as
> he is a Foster   Right now he is on purefied liquid Venus Fly Trap
> per a complementary Vet who is well regarded in the local
> community...which she says helped her keep her own cats tumor at bay for
> nine months (  This lady is not simply " out there"... but I have not
> yet done any looking re: VFT as I was not planning to prolong Gilbies
> life.. Just to make him comfortable and keep him out of the shelter
> during his final days  Now, of course, having gotten so used to and
> loving having him with me I am interested in how to keep him painlessly
> around with me longer  I like watching TV with a 15 lb cat sitting
> on my chest with his face inches from my own... snoring..
>
> Bob
>
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Re: [Felvtalk] Gilbert...

[dlgegg]

They do get under our skin and become a necessary to our lives.  I have 3 15 
pounders who think I am a mattress for them to sleep on.  Thank God they take 
turns.  Does Gilbert like to KNEED a lot?  Homey gets into a trance and digs 
deeply so I have had to explain to doctors what all those little red spots are. 
 Do you have to foster, or can you just adopt so you can give pain treatment as 
you see fit?
I end up adopting everyone that comes my way.  After just a couple of days I 
could not let them go.

 ROBERT CHAPEL  wrote: 
> 

Amani...
As always... thank you for the advice and all the other references to 
research ( Doxy, Cannabinol) that can be helpful down the road...   In 
the case of Gilbert it is perplexing that they are so withholding re: 
drugs.  Gilbert is a favorite of everyone and no one wants to see him 
hurting  I'll keep making suggestions.  Starting once again to pay 
my own ( larger) medical contributions under medicare I cannot afford to 
be taking him to vets on my own ( as well as it being a potential 
problem if I do because he is ( technically) the shelters " property as 
he is a Foster   Right now he is on purefied liquid Venus Fly Trap 
per a complementary Vet who is well regarded in the local 
community...which she says helped her keep her own cats tumor at bay for 
nine months (  This lady is not simply " out there"... but I have not 
yet done any looking re: VFT as I was not planning to prolong Gilbies 
life.. Just to make him comfortable and keep him out of the shelter 
during his final days  Now, of course, having gotten so used to and 
loving having him with me I am interested in how to keep him painlessly 
around with me longer  I like watching TV with a 15 lb cat sitting 
on my chest with his face inches from my own... snoring..

Bob

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Re: [Felvtalk] Gilbert...

[ROBERT CHAPEL]

Amani...
As always... thank you for the advice and all the other references to 
research ( Doxy, Cannabinol) that can be helpful down the road...   In 
the case of Gilbert it is perplexing that they are so withholding re: 
drugs.  Gilbert is a favorite of everyone and no one wants to see him 
hurting  I'll keep making suggestions.  Starting once again to pay 
my own ( larger) medical contributions under medicare I cannot afford to 
be taking him to vets on my own ( as well as it being a potential 
problem if I do because he is ( technically) the shelters " property as 
he is a Foster   Right now he is on purefied liquid Venus Fly Trap 
per a complementary Vet who is well regarded in the local 
community...which she says helped her keep her own cats tumor at bay for 
nine months (  This lady is not simply " out there"... but I have not 
yet done any looking re: VFT as I was not planning to prolong Gilbies 
life.. Just to make him comfortable and keep him out of the shelter 
during his final days  Now, of course, having gotten so used to and 
loving having him with me I am interested in how to keep him painlessly 
around with me longer  I like watching TV with a 15 lb cat sitting 
on my chest with his face inches from my own... snoring..


Bob

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Re: [Felvtalk] Destiny..

[dlgegg]

I have learned from Annie and others that I need to check out every 
possibility, not just the obvious.  Had I done so, we might have caught the 
kidney problem in time.  My vet has since done some research and found that 
with FELV cats, kidney problem are one of the first signs, just sorry that 
Annie had to suffer and die because we did not know that earlier.

 Marilyn Knapp Litt  wrote: 
> I am so sorry to hear about Gilbert. This sounds like much the same 
> progression.  The sinus drip was from the pressure, although we didn't know 
> that.  We just knew it was not bacterial.  
> 
> Her head started to swell and she didn't have the energy or strength to go to 
> her favorite spots.  (The cats rotated in a fair fashion.)  I hope Gilbert 
> will not take the same course, but it was only a few days after her eye was 
> closed that we made our decision. 
> 
> So sorry to hear about Gilbert and so wonderful to hear he spent his short 
> time in such a loving home.
> 
> Marilyn
> 
> -Original Message-
> From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of 
> ROBERT CHAPEL
> Sent: Sunday, June 25, 2017 8:55 AM
> To: felvtalk@felineleukemia.org
> Subject: Re: [Felvtalk] Destiny..
> 
> Marilyn...
> So Sorry to  hear about Destiny... was afraid it was something like this when 
> it was discovered  that she was FeLV+  My Current Cat (
> Gilbert) is suffering much the same fate ( apart from the FeLV)... I am 
> keeping him on Prednisolone to keep the tumor in check for as long as we 
> can... and just last week he developed what appeared to be a sinus infection 
> ( though none of his exudate is purulent at this point) In his case the tumor 
> makes it impossible to _ close_ one of his eyes all the way( so I give him 
> drops several times a day to keep some moisture on the eyeball  We'll put 
> him down at the point that he stops eating or appears to be in severe pain... 
> neither has happened as yet...  I will miss him terribly... he is one of the 
> nicest cats I have ever met... Appears we have all been very fortunate to 
> have beautiful kitties with terrific personalities in our care and equally 
> unfortunate in losing them SO far before their reasonable time Your girl 
> sounds like she was a sweetie.  I am sorry...
> Bob
> 
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Re: [Felvtalk] Gilbert

[Amani Oakley]

Bob

I know you have had trouble with the clinic in terms of offering you 
medications, but if it were me, I would also want to try dexamethasone by 
injection if possible. It is much more powerful than the prednisone in reducing 
swelling and helping in reducing pain and neurological symptoms in brain 
lesions.

Amani
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Re: [Felvtalk] Destiny..

[Marilyn Knapp Litt]

I am so sorry to hear about Gilbert. This sounds like much the same 
progression.  The sinus drip was from the pressure, although we didn't know 
that.  We just knew it was not bacterial.  

Her head started to swell and she didn't have the energy or strength to go to 
her favorite spots.  (The cats rotated in a fair fashion.)  I hope Gilbert will 
not take the same course, but it was only a few days after her eye was closed 
that we made our decision. 

So sorry to hear about Gilbert and so wonderful to hear he spent his short time 
in such a loving home.

Marilyn

-Original Message-
From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of ROBERT 
CHAPEL
Sent: Sunday, June 25, 2017 8:55 AM
To: felvtalk@felineleukemia.org
Subject: Re: [Felvtalk] Destiny..

Marilyn...
So Sorry to  hear about Destiny... was afraid it was something like this when 
it was discovered  that she was FeLV+  My Current Cat (
Gilbert) is suffering much the same fate ( apart from the FeLV)... I am keeping 
him on Prednisolone to keep the tumor in check for as long as we can... and 
just last week he developed what appeared to be a sinus infection ( though none 
of his exudate is purulent at this point) In his case the tumor makes it 
impossible to _ close_ one of his eyes all the way( so I give him drops several 
times a day to keep some moisture on the eyeball  We'll put him down at the 
point that he stops eating or appears to be in severe pain... neither has 
happened as yet...  I will miss him terribly... he is one of the nicest cats I 
have ever met... Appears we have all been very fortunate to have beautiful 
kitties with terrific personalities in our care and equally unfortunate in 
losing them SO far before their reasonable time Your girl sounds like she 
was a sweetie.  I am sorry...
Bob

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Re: [Felvtalk] Destiny..

[ROBERT CHAPEL]

Marilyn...
So Sorry to  hear about Destiny... was afraid it was something like this 
when it was discovered  that she was FeLV+  My Current Cat ( 
Gilbert) is suffering much the same fate ( apart from the FeLV)... I am 
keeping him on Prednisolone to keep the tumor in check for as long as we 
can... and just last week he developed what appeared to be a sinus 
infection ( though none of his exudate is purulent at this point) In his 
case the tumor makes it impossible to _ close_ one of his eyes all the 
way( so I give him drops several times a day to keep some moisture on 
the eyeball  We'll put him down at the point that he stops eating or 
appears to be in severe pain... neither has happened as yet...  I will 
miss him terribly... he is one of the nicest cats I have ever met...  
Appears we have all been very fortunate to have beautiful kitties with 
terrific personalities in our care and equally unfortunate in losing 
them SO far before their reasonable time Your girl sounds like she 
was a sweetie.  I am sorry...

Bob

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Re: [Felvtalk] Doxycycline

[Amani Oakley]

Ardy - there are a number of publications which deal with the mode of action of 
Doxycycline and its antiviral properties. It doesn’t kill the virus but 
inhibits its replication, sometimes by interfering with cell wall development 
and other times by preventing the virus from penetrating cells. Viruses usually 
replicate by invading a normal host cell, taking over its "machinery" and 
basically getting the host cell to make millions more viruses, which are then 
released into the circulation when the cell bursts. Doxycycline has been shown 
to sometimes inhibit the penetration of the virus into the cell.

So for example, Doxycycline has been found to be effective against Dengue 
fever. There are a number of publications exploring the effectiveness with 
Dengue fever. Here is an excerpt from a 2014 publication from the Archives of 
Virology (Inhibitory Effect of Doxycycline against Dengue Virus Replication in 
Vitro):

"Doxycycline is an antibiotic derived from tetracycline that possesses 
antimicrobial and anti-inflammatory activities. Antiviral activity of 
doxycycline against dengue virus has been reported previously; however, its 
anti-dengue properties need further investigation. This study was conducted to 
determine the potential activity of doxycycline against dengue virus 
replication in vitro. Doxycycline inhibited the dengue virus serine protease 
(DENV2 NS2B-NS3pro) with an IC50 value of 52.3 ± 6.2 μM at 37 °C (normal human 
temperature) and 26.7 ± 5.3 μM at 40 °C (high fever temperature). The antiviral 
activity of doxycycline was first tested at different concentrations against 
DENV2 using a plaque-formation assay. The virus titter decreased significantly 
after applying doxycycline at levels lower than its 50 % cytotoxic 
concentration (CC50, 100 μM), showing concentration-dependent inhibition with a 
50 % effective concentration (EC50) of approximately 50 μM. Doxycycline 
significantly inhibited viral entry and post-infection replication of the four 
dengue serotypes, with serotype-specific inhibition (high activity against 
DENV2 and DENV4 compared to DENV1 and DENV3). Collectively, these findings 
underline the need for further experimental and clinical studies on 
doxycycline, utilizing its anti-dengue and anti-inflammatory activities to 
attenuate the clinical symptoms of dengue virus infection."

Doxycycline has also been found to be effective against West Nile virus, 
reovirus, Japanese encephalitis virus (JEV), vesicular stomatitis virus (in 
vitro), mural virus (a mouse virus which causes leukemia in mice), and more. 
Doxycycline is also effective against more unusual organisms like protozoa (eg 
- malaria) and the unusual bacteria which cause Lyme Disease and Rocky Mountain 
Spotted Fever.

Unbelievably, Doxycycline has also been shown to suppress metastatic cancer or 
assist in bone metastatses. I suspect this last finding is not a strong one 
since I don’t know that Doxycycline is routinely used for this. However, I sure 
wish I had known this when my family member was suffering from cancer. Again, 
under the category of "it might not do a darn thing but it's unlikely to be 
worse than the situation you're facing", I would have given this a try. There 
are quite a few publications looking at the use of Doxy for cancer though, so I 
think there is probably something there.

I doubt that anyone is studying the effect on the Feline Leukemia virus because 
I see little research involving cat conditions generally, and even less focused 
on the Feline Leukemia virus. I obviously went looking for an explanation as to 
why Doxycycline and Winstrol might have been effective with Zander, because I 
too had the general understanding that antibiotics are not effective against 
viruses (and I have a Microbiology degree!). I suspect that most physicians and 
vets have also had this "rule of thumb" hammered into their heads. It is 
generally true of course, but it obviously works to create a blind spot for 
physicians and vets, when it comes to the "exceptions" to this general rule. 
Also, what I have also come to understand is that when there is a drug like 
Doxycycline (and Winstrol), which has been around for a long time and the drug 
companies no longer have a patent on it, they can't make money on it, so they 
stop doing any research related to it. They focus their research on their new 
drugs on which they hold patents, so they can push these, and make more money.

And don’t even get me started on cannabis oil. To imagine where society might 
have been if we'd focused on researching the effects of cannabis on everything 
from cold sores to cancer for the last 100 years, is to truly despair at the 
sheer stupidity and duplicity of governments and certain people with devious 
designs. Oh, and cannabis' entirely benign cousin - hemp - which got swept into 
the ban for no legitimate reason at all - is able to be used for everything 
from a food source, to clothing, to fertilizer, to