CSMolecula Silver .. comments please

2008-05-18 Thread Pat
The link you sent said not found.  This is what I found at Sloan-Kettering 

(  http://www.mskcc.org/mskcc/html/69189.cfm  ) , not exactly what I wanted to 
hear.  


 Pat

Common Name
Silver Proteins, Colloidal Silver Proteins, Colloidal Silver Water
top


Clinical Summary
Colloidal
silver consists of silver particles suspended in a liquid. It is often
produced by home-made generators. The use of silver medicinals to treat
disorders such as epilepsy, gonorrhea, and colds was not uncommon until
the mid-20th century. However, silver was replaced by safer therapies
in the recent decades. While silver compounds are still used in
external preparations as antiseptics, there has been a growing interest
in using the collodial form of silver orally as an alternative
medicine. Although no human clinical data support the use of oral
colloidal silver, it is being promoted as a cure for AIDS, cancer, and
diabetes. Silver is not an essential mineral and does not serve any
physiological function in the body. It actually denatures proteins by
binding to their reactive groups. It can inactivate some enzymes by
forming hemisilver sulfides with sulfhydryl groups of the enzymes (1).
Silver when taken orally can interact with and reduce the effectiveness
of tetracycline, quinolone, and penicillamine. Long term use can cause
silver deposition in the skin and mucous membranes leading to an
irreversible condition called argyria, characterized by bluish-gray to
gray-black pigmentation (2) (3). Other adverse effects include seizures (6) and 
kidney damage. Pregnant women should not consume colloidal silver as it can 
cause developmental abnormalities in the fetus (1).
top


Purported uses
* AIDS 
* Cancer treatment 
* Diabetes 
* Immunostimulation 
* Infections 
top


Constituents
* Silver particles suspended in liquid.
top


Mechanism of Action
Silver
is unstable in suspension form and can bind to proteins. Silver
compounds form hemisilver sulfides with sulfhydryl groups that leads to
inactivation of enzymes. Silver also has the ability to bind amino,
carboxyl, phosphate and imidazole groups (1).
Studies have shown that silver accumulates in rat liver and binds with
various tissues and basal membranes. It also affects the activities of
lactate dehydrogenase and glutathione peroxidase and the peroxidation
of membrane lipids (4).
top


Pharmacokinetics
Approximately
10% of silver salts may be absorbed following ingestion, with increased
absorption from ruptured mucus membranes and skin wounds. The half-life
varies from several days to months but silver deposited in the skin has
a much longer half-life. It is excreted into the bile and eliminated in
the feces (1).
top


Warnings
The
Food and Drug Administration (FDA) declared that all over-the-counter
drugs containing colloidal silver are not recognized as safe and
effective and are misbranded (7).
The FDA has also recently issued letters to website operators of
colloidal silver warning them that it is illegal to promote such
products online (8).
top


Contraindications
Pregnant women should not use colloidal silver as it can cause developmental 
abnormalities in the fetus (1).
top


Adverse Reactions
Reported (Oral): Accumulation
of silver in the body causes argyria, a bluish-gray discoloration of
the skin, which is untreatable. Other effects include seizures and
kidney damage. 
Reported (Topical): Topical use of silver nitrate for burns may cause 
methemoglobinemia. 
Exposure to high concentrations of silver, such as in an industrial setting, 
leads to systemic toxicity (1) (5).
top


Herb-Drug Interactions
* Antibiotics: Colloidal silver can reduce the bioavailability of 
antibiotics such as tetracycline and quinolone. 
* Penicillamine: Colloidal silver can reduce the effectiveness of drugs 
such as penicillamine by binding to the drug.
top


Literature Summary and Critique
No
human studies have been conducted to test the medicinal effects of
colloidal silver. There are a few case reports on its toxicity. 

McKenna JK, et al Argyria associated with colloidal silver supplementation. Int 
J Dermatol 2003; 42(7):549. 
A
65-year old male developed skin discoloration but had no other
symptoms. He had consumed colloidal silver supplements for two years
for treatment of diabetes. The discoloration was limited to fingernails
but could not be treated by depigmenting creams or chelation. The
patient was advised to use sunscreens to prevent further pigmentary
changes. 

Gulbranson SH, Hud JA, Hansen RC. Argyria 

Re: CSMolecula Silver .. comments please

2008-05-18 Thread Arnold Beland
Please note that they are talking about Silver Proteins, Colloidal Silver 
Proteins, which relate to the original post concerning the lastest form of 
snake oil, not what we make here.

Best Regards,
Arnold Beland
www.atlasnova.com
- Original Message - 
From: Pat pattycake29...@yahoo.com

To: silver list silver-list@eskimo.com
Sent: Sunday, May 18, 2008 4:13 PM
Subject: CSMolecula Silver .. comments please



The link you sent said not found.  This is what I found at Sloan-Kettering

(  http://www.mskcc.org/mskcc/html/69189.cfm  ) , not exactly what I 
wanted to hear.



Pat

Common Name
Silver Proteins, Colloidal Silver Proteins, Colloidal Silver Water
top


Clinical Summary
Colloidal
silver consists of silver particles suspended in a liquid. It is often
produced by home-made generators. The use of silver medicinals to treat
disorders such as epilepsy, gonorrhea, and colds was not uncommon until
the mid-20th century. However, silver was replaced by safer therapies
in the recent decades. While silver compounds are still used in
external preparations as antiseptics, there has been a growing interest
in using the collodial form of silver orally as an alternative
medicine. Although no human clinical data support the use of oral
colloidal silver, it is being promoted as a cure for AIDS, cancer, and
diabetes. Silver is not an essential mineral and does not serve any
physiological function in the body. It actually denatures proteins by
binding to their reactive groups. It can inactivate some enzymes by
forming hemisilver sulfides with sulfhydryl groups of the enzymes (1).
Silver when taken orally can interact with and reduce the effectiveness
of tetracycline, quinolone, and penicillamine. Long term use can cause
silver deposition in the skin and mucous membranes leading to an
irreversible condition called argyria, characterized by bluish-gray to
gray-black pigmentation (2) (3). Other adverse effects include seizures 
(6) and kidney damage. Pregnant women should not consume colloidal silver 
as it can cause developmental abnormalities in the fetus (1).

top


Purported uses
* AIDS
* Cancer treatment
* Diabetes
* Immunostimulation
* Infections
top


Constituents
* Silver particles suspended in liquid.
top


Mechanism of Action
Silver
is unstable in suspension form and can bind to proteins. Silver
compounds form hemisilver sulfides with sulfhydryl groups that leads to
inactivation of enzymes. Silver also has the ability to bind amino,
carboxyl, phosphate and imidazole groups (1).
Studies have shown that silver accumulates in rat liver and binds with
various tissues and basal membranes. It also affects the activities of
lactate dehydrogenase and glutathione peroxidase and the peroxidation
of membrane lipids (4).
top


Pharmacokinetics
Approximately
10% of silver salts may be absorbed following ingestion, with increased
absorption from ruptured mucus membranes and skin wounds. The half-life
varies from several days to months but silver deposited in the skin has
a much longer half-life. It is excreted into the bile and eliminated in
the feces (1).
top


Warnings
The
Food and Drug Administration (FDA) declared that all over-the-counter
drugs containing colloidal silver are not recognized as safe and
effective and are misbranded (7).
The FDA has also recently issued letters to website operators of
colloidal silver warning them that it is illegal to promote such
products online (8).
top


Contraindications
Pregnant women should not use colloidal silver as it can cause 
developmental abnormalities in the fetus (1).

top


Adverse Reactions
Reported (Oral): Accumulation
of silver in the body causes argyria, a bluish-gray discoloration of
the skin, which is untreatable. Other effects include seizures and
kidney damage.
Reported (Topical): Topical use of silver nitrate for burns may cause 
methemoglobinemia.
Exposure to high concentrations of silver, such as in an industrial 
setting, leads to systemic toxicity (1) (5).

top


Herb-Drug Interactions
* Antibiotics: Colloidal silver can reduce the bioavailability of 
antibiotics such as tetracycline and quinolone.
* Penicillamine: Colloidal silver can reduce the effectiveness of drugs 
such as penicillamine by binding to the drug.

top


Literature Summary and Critique
No
human studies have been conducted to test the medicinal effects of
colloidal silver. There are a few case reports on its toxicity.

McKenna JK, et al Argyria associated with colloidal silver 
supplementation. Int J Dermatol 2003; 42(7):549.

A
65-year old male developed skin discoloration but had no other
symptoms. He had consumed colloidal silver supplements for two years
for treatment

Re: CSMolecula Silver .. comments please

2008-05-18 Thread Gene Wolfe
And what would anyone expect from a mainline medical establishment? 
The key to this statement is: Although no human clinical data 
support the use of oral

colloidal silver, it is being promoted as a cure for AIDS, cancer, and
diabetes.
Of course there is no clinical data, what Big Pharma company would 
spend the money to do clinical studies when they could not patent the 
product and make money off of it? This says nothing about the 
effectiveness of CS. No one on this list wants to spend the money to 
collect clinical data, so there is no data.


The FDA is a branch of Big Pharma, so they are not going to say 
anything good about CS. And the examples tell nothing about what the 
CS product was that they site.


The information from this list is much more valuable.

Gene


At 06:13 PM 5/18/2008, you wrote:

The link you sent said not found.  This is what I found at Sloan-Kettering

(  http://www.mskcc.org/mskcc/html/69189.cfm  ) , not exactly what I 
wanted to hear.



Pat

Common Name
Silver Proteins, Colloidal Silver Proteins, Colloidal Silver Water
top


Clinical Summary
Colloidal
silver consists of silver particles suspended in a liquid. It is often
produced by home-made generators. The use of silver medicinals to treat
disorders such as epilepsy, gonorrhea, and colds was not uncommon until
the mid-20th century. However, silver was replaced by safer therapies
in the recent decades. While silver compounds are still used in
external preparations as antiseptics, there has been a growing interest
in using the collodial form of silver orally as an alternative
medicine. Although no human clinical data support the use of oral
colloidal silver, it is being promoted as a cure for AIDS, cancer, and
diabetes. Silver is not an essential mineral and does not serve any
physiological function in the body. It actually denatures proteins by
binding to their reactive groups. It can inactivate some enzymes by
forming hemisilver sulfides with sulfhydryl groups of the enzymes (1).
Silver when taken orally can interact with and reduce the effectiveness
of tetracycline, quinolone, and penicillamine. Long term use can cause
silver deposition in the skin and mucous membranes leading to an
irreversible condition called argyria, characterized by bluish-gray to
gray-black pigmentation (2) (3). Other adverse effects include 
seizures (6) and kidney damage. Pregnant women should not consume 
colloidal silver as it can cause developmental abnormalities in the fetus (1).

top


Purported uses
* AIDS
* Cancer treatment
* Diabetes
* Immunostimulation
* Infections
top


Constituents
* Silver particles suspended in liquid.
top


Mechanism of Action
Silver
is unstable in suspension form and can bind to proteins. Silver
compounds form hemisilver sulfides with sulfhydryl groups that leads to
inactivation of enzymes. Silver also has the ability to bind amino,
carboxyl, phosphate and imidazole groups (1).
Studies have shown that silver accumulates in rat liver and binds with
various tissues and basal membranes. It also affects the activities of
lactate dehydrogenase and glutathione peroxidase and the peroxidation
of membrane lipids (4).
top


Pharmacokinetics
Approximately
10% of silver salts may be absorbed following ingestion, with increased
absorption from ruptured mucus membranes and skin wounds. The half-life
varies from several days to months but silver deposited in the skin has
a much longer half-life. It is excreted into the bile and eliminated in
the feces (1).
top


Warnings
The
Food and Drug Administration (FDA) declared that all over-the-counter
drugs containing colloidal silver are not recognized as safe and
effective and are misbranded (7).
The FDA has also recently issued letters to website operators of
colloidal silver warning them that it is illegal to promote such
products online (8).
top


Contraindications
Pregnant women should not use colloidal silver as it can cause 
developmental abnormalities in the fetus (1).

top


Adverse Reactions
Reported (Oral): Accumulation
of silver in the body causes argyria, a bluish-gray discoloration of
the skin, which is untreatable. Other effects include seizures and
kidney damage.
Reported (Topical): Topical use of silver nitrate for burns may 
cause methemoglobinemia.
Exposure to high concentrations of silver, such as in an industrial 
setting, leads to systemic toxicity (1) (5).

top


Herb-Drug Interactions
* Antibiotics: Colloidal silver can reduce the 
bioavailability of antibiotics such as tetracycline and quinolone.
* Penicillamine: Colloidal silver can reduce the 
effectiveness of drugs such as penicillamine by binding to the drug.

Re: CSMolecula Silver .. comments please

2008-05-18 Thread Michael Zangari
I guess my reaction is typically me.
Does it really matter if the effectiveness is broadly
excepted?
Silver kill bacteria. Case Closed.
Molecular? Isn't everything? It isn't magnetic. That
changes everything.
i guess I feel no evangelistic tendency towards the
usage of anything unless it is threatened by a law
that changes access and usage rights.
I'd like to see as much research as possible. I am not
threatened by spin. Everything goes into the
information pot.
  =z=
--- Pat pattycake29...@yahoo.com wrote:

 The link you sent said not found.  This is what I
 found at Sloan-Kettering 
 
 (  http://www.mskcc.org/mskcc/html/69189.cfm  ) ,
 not exactly what I wanted to hear.  
 
 
 Pat
 
 Common Name
 Silver Proteins, Colloidal Silver Proteins,
 Colloidal Silver Water
 top
 
 
 Clinical Summary
 Colloidal
 silver consists of silver particles suspended in a
 liquid. It is often
 produced by home-made generators. The use of silver
 medicinals to treat
 disorders such as epilepsy, gonorrhea, and colds was
 not uncommon until
 the mid-20th century. However, silver was replaced
 by safer therapies
 in the recent decades. While silver compounds are
 still used in
 external preparations as antiseptics, there has been
 a growing interest
 in using the collodial form of silver orally as an
 alternative
 medicine. Although no human clinical data support
 the use of oral
 colloidal silver, it is being promoted as a cure for
 AIDS, cancer, and
 diabetes. Silver is not an essential mineral and
 does not serve any
 physiological function in the body. It actually
 denatures proteins by
 binding to their reactive groups. It can inactivate
 some enzymes by
 forming hemisilver sulfides with sulfhydryl groups
 of the enzymes (1).
 Silver when taken orally can interact with and
 reduce the effectiveness
 of tetracycline, quinolone, and penicillamine. Long
 term use can cause
 silver deposition in the skin and mucous membranes
 leading to an
 irreversible condition called argyria, characterized
 by bluish-gray to
 gray-black pigmentation (2) (3). Other adverse
 effects include seizures (6) and kidney damage.
 Pregnant women should not consume colloidal silver
 as it can cause developmental abnormalities in the
 fetus (1).
 top
 
 
 Purported uses
   * AIDS 
   * Cancer treatment 
   * Diabetes 
   * Immunostimulation 
   * Infections 
 top
 
 
 Constituents
   * Silver particles suspended in liquid.
 top
 
 
 Mechanism of Action
 Silver
 is unstable in suspension form and can bind to
 proteins. Silver
 compounds form hemisilver sulfides with sulfhydryl
 groups that leads to
 inactivation of enzymes. Silver also has the ability
 to bind amino,
 carboxyl, phosphate and imidazole groups (1).
 Studies have shown that silver accumulates in rat
 liver and binds with
 various tissues and basal membranes. It also affects
 the activities of
 lactate dehydrogenase and glutathione peroxidase and
 the peroxidation
 of membrane lipids (4).
 top
 
 
 Pharmacokinetics
 Approximately
 10% of silver salts may be absorbed following
 ingestion, with increased
 absorption from ruptured mucus membranes and skin
 wounds. The half-life
 varies from several days to months but silver
 deposited in the skin has
 a much longer half-life. It is excreted into the
 bile and eliminated in
 the feces (1).
 top
 
 
 Warnings
 The
 Food and Drug Administration (FDA) declared that all
 over-the-counter
 drugs containing colloidal silver are not recognized
 as safe and
 effective and are misbranded (7).
 The FDA has also recently issued letters to website
 operators of
 colloidal silver warning them that it is illegal to
 promote such
 products online (8).
 top
 
 
 Contraindications
 Pregnant women should not use colloidal silver as it
 can cause developmental abnormalities in the fetus
 (1).
 top
 
 
 Adverse Reactions
 Reported (Oral): Accumulation
 of silver in the body causes argyria, a bluish-gray
 discoloration of
 the skin, which is untreatable. Other effects
 include seizures and
 kidney damage. 
 Reported (Topical): Topical use of silver nitrate
 for burns may cause methemoglobinemia. 
 Exposure to high concentrations of silver, such as
 in an industrial setting, leads to systemic toxicity
 (1) (5).
 top
 
 
 Herb-Drug Interactions
   * Antibiotics: Colloidal silver can reduce the
 bioavailability of antibiotics such as tetracycline
 and quinolone. 
   * Penicillamine: Colloidal silver can reduce the
 effectiveness of drugs such as penicillamine by
 binding to the drug.
 top
 
 
 

Re: CSMolecula Silver .. comments please

2008-05-18 Thread Arnold Beland
Gene writes,
Of course there is no clinical data, what Big Pharma company would
spend the money to do clinical studies when they could not patent the
product and make money off of it? This says nothing about the
effectiveness of CS. No one on this list wants to spend the money to
collect clinical data, so there is no data.

There is simply no mechanism to support the expense of a thorough
investigation into the effectiveness or lack thereof as a method of
dealing with various bacteria, viruses or fungi. It is extremely easy
for anyone to make colloidal silver, which is eighty percent Ionic and
fifteen to twenty percent particulate. It is also a fact that it does
not lend itself to shipment and storage after being made. The particles
are held in suspension by Brownian motion and the Ionic portion exists
in solution due to a mutually repulsive electrical charge of individual
atoms. Vibration or external stimulus including photons tends to cause
these particles to agglomerate and fall out of solution. All that being
said, it is still a very useful product. We will probably never know
precisely why it works as it does as there is simply no money in it. 
And
money, after all, is what makes the world go round. 

And what would anyone expect from a mainline medical establishment?

If you are ever so unfortunate as to have a serious illness that chug-a
lugging CS doesn't fix, you might be grateful they exist.

The FDA is a branch of Big Pharma

If this were true I doubt that our toddlers would now be chewing on 
lead painted toys from China.

The information from this list is much more valuable.

We can certainly agree on that.  One of the most useful functions of the list 
is the de-bunking of items such as 
Molecula Silver, that is supposed to be smaller than a single atom, LOL.



Best Regards,
Arnold Beland
www.atlasnova.com

  - Original Message - 
  From: Gene Wolfe 
  To: silver-list@eskimo.com 
  Sent: Sunday, May 18, 2008 5:56 PM
  Subject: Re: CSMolecula Silver .. comments please


  And what would anyone expect from a mainline medical establishment? The key 
to this statement is: Although no human clinical data support the use of oral
  colloidal silver, it is being promoted as a cure for AIDS, cancer, and
  diabetes. 
  Of course there is no clinical data, what Big Pharma company would spend the 
money to do clinical studies when they could not patent the product and make 
money off of it? This says nothing about the effectiveness of CS. No one on 
this list wants to spend the money to collect clinical data, so there is no 
data. 

  The FDA is a branch of Big Pharma, so they are not going to say anything good 
about CS. And the examples tell nothing about what the CS product was that they 
site. 

  The information from this list is much more valuable.

  Gene


  At 06:13 PM 5/18/2008, you wrote:

The link you sent said not found.  This is what I found at Sloan-Kettering 

(  http://www.mskcc.org/mskcc/html/69189.cfm ) , not exactly what I wanted 
to hear.  


 Pat