Re: [ccp4bb] AlphaFold: more thinking and less pipetting (?)

2020-12-04 Thread Ioannis Vakonakis
In defence of experimental science, may I also suggest that the models AlphaFold2 and other predictors worked on were derived from sequences for which they knew a well-defined structure is possible. Much of the work we do is exactly on taking unwieldy sequences with disordered elements,

[ccp4bb] Postdoctoral position on novel method for protein crystallisation

2018-07-25 Thread Ioannis Vakonakis
Dear colleagues, A postdoctoral position is available immediately in my group jointly with the lab of Maike Bublitz, in the Department of Biochemistry, Oxford. The aim of this BBSRC-funded post is to develop a novel methodology for membrane protein crystallisation that utilises NMR-derived

[ccp4bb] ATPase inhibitor

2017-05-30 Thread Ioannis Vakonakis
Dear colleagues, Apologies for the non-crystallographic question. I was wondering if anyone knows of broad-spectrum inhibitors of the ATPase type common in Hexokinase, Hsp70, actin etc, appart from nucleotide analogues. If you could point to literature on such inhibitors that would be even

[ccp4bb] Postdoctoral position in structural biology in Oxford

2015-12-09 Thread Ioannis Vakonakis
Dear all, We seek to appoint a highly motivated Postdoctoral Research Associate in the laboratory of Professor John Vakonakis for studies of proteins involved in centriole assembly. The successful candidate will join a multidisciplinary collaboration between Oxford and the groups of Professors

Re: [ccp4bb] Postdoctoral position in Structural Biology at Oxford University

2013-08-03 Thread Ioannis Vakonakis
Dear all, Apologies for sending this postdoc position announcement twice. It has come to my attention that the link I provided for the online application and job details is broken; the following one should work: