surrounding condition.
2) If the crystals indeed contain the protein of interest, they can be used
for various seeding methods. I've got results from both streak and micro
seeding.
Best,
Tuhin.
Tuhin Bhowmick
Department of Physics
Indian Institute of Science
Bangalore: 560012
Email: tuhin.i
Hi Jens,
You can try NAMOT (Nucleic Acid MOdelling Tool), from the links below.
http://namot.sourceforge.net/
http://sourceforge.net/projects/namot/
Best,
Tuhin.
Tuhin Bhowmick
Prof. S. Ramakumar’s Lab
Biocrystallography and Computation
Department of Physics
Indian Institute of Science
Dear friends,
here I'm summarizing all of your suggestions regarding dissolving a
hydrophobic ligand (in this case, containig benzoic acid moities) for
crystallization and biochemical assays:
1)Sodium salts of benzoic acid containing molecules can often be soluble
in water to high
Dear All,
does anyone have any clever suggestion/s for handling the solubility problem
of highly hydrophobic compound, during co-crystallization or inhibition
assays? The ligands I am using are almost insoluble in aquous medium
(precipitates out or becomes turbid at ~1 micro molar conc.). In
Dear all:
I am working on the aspherical atom refinement of a small molecule using
the XD package. The program provides you with the option of selecting a
refinement strategy against F or F^2. I have noticed that the R-factors
and GOFs calculated based on F^2 are larger in magnitude compared to
