Dear Uma,
A very complehensive survey of the state-of-the-art in this topic can be found
in the following literature resources:
(1)
Garman EF.
Radiation damage in macromolecular crystallography: what is it and why should
we care?
Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):339-51.
Collect small slices of data (instead of a complete data set) on several
crystals then merge the data together to get a full data set.
The slices of must be small enough so that the damage to the S-NO group is
still very limited on each slice. You may have to play with beam attenuation a
bit,
Dear All:
Many thanks for your commoents and advice.
I will keep them in mind.
Uma
On Thu, Feb 14, 2013 at 7:54 AM, Fischmann, Thierry
thierry.fischm...@merck.com wrote:
Collect small slices of data (instead of a complete data set) on several
crystals then merge the data together to get a
Maybe you can try different energies hoping that damage is wavelength
dependent. It must be dose dependent though, so you may consider merging short
sweeps from multiple crystals.
Original message
From: Uma Ratu rosiso2...@gmail.com
Date:
To: CCP4BB@JISCMAIL.AC.UK
