We are looking for an ambitious and highly-motivated postdoctoral research
associate who has expertise in protein crystallography to join the team of Dr
Richard Bayliss within the Department of Biochemistry. The position is funded
by a 5-year Cancer Research UK Programme Grant, which provides a generous
allowance for equipment, running costs and research support.
Research in the Bayliss lab is focussed on the structural mechanisms by which
cell division is regulated, and on the structure-based design of
chemotherapeutics. The group has built an international reputation for
excellence in these fields, and has published 10 papers in peer-reviewed
journals in the past 3 years.
The main objective of this new position will be to elucidate the regulatory
mechanisms of separase, the protease that triggers chromosome segregation. This
is a high-impact project that will address a long-standing, unresolved question
in mitosis and which is supported by several years of pilot work. The
researcher will also contribute to the other aspects of the programme, such as
the pathways of regulation by protein kinases (Aurora-A, Neks) and the early
prophase checkpoint (CHFR).
Dr Bayliss’s research group is located in the state-of-the-art Henry Wellcome
Building with access to excellent facilities for biochemical studies,
structural biology, cell culture (including large-scale insect and mammalian
cell expression), microscopy and computer analysis. The position is available
from January for three years in the first instance, renewable for a further two
years depending on progress. The appointment will be made within the salary
range £30,870 - £35,788. Prospective candidates should hold a degree and Ph.D
in biochemistry, or related discipline, and have proven expertise in X-ray
crystallography through the publication of at least one first author paper in a
major international journal.
Informal enquiries can be directed to Dr Bayliss via email
(richard.bayl...@le.ac.uk). Applications must be made through the Job Vacancies
page of the University website, job reference MBP00499.
The closing date for this post is midnight on 6th December 2011.
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Dr Richard Bayliss, Reader in Structural Biology
Department of Biochemistry
Henry Wellcome Building
University of Leicester
Lancaster Road, Leicester
LE2 9HN
Tel: 0116 2297100
Web: http://www2.le.ac.uk/departments/biochemistry/staff/richard-bayliss/
