[ccp4bb] PhD studentship at the University of Exeter

Dear CCP4-ers, A PhD studentship in biochemistry and structural biology is available at the University of Exeter. The focus for this project will be toxin-antitoxin modules in the human pathogen Burkholderia pseudomallei, and their role in rendering bacteria resistant to antibiotics. The start

[ccp4bb] Postdoctoral position available

A postdoctoral position is available to join the lab of Dr. Nicholas Harmer, at the University of Exeter, UK, from 1st October 2010. The position is funded by the BBSRC to work on the structure and function of three novel proteins involved in the biosynthesis of the capsular polysaccharide of

[ccp4bb] Phasing statistics

Dear CCP4ers, I've been asked by a referee to provide the phasing statistics for a SAD dataset that I used to solve a recent structure. Whilst I have been able to find a figure-of-merit for the data after phasing, I can't work out how to get any other statistics (e.g. phasing power or an

[ccp4bb] Summary: Phasing statistics

Dear Colleagues, I am very grateful to everyone who contributed to the discussion regarding phasing statistics that I initiated. I certainly found it very informative. Below is a summary of the technical responses that I regarding this problem. 1) Use some of the statistics that SHELXD and

[ccp4bb] Structure-function PhD position (UK only)

Dear all, I have a PhD position in my laboratory, starting in September 2015. The position will be looking to elucidate the biosynthetic pathway for two unusual sugars from Coxiella, and will have good opportunities for interesting structural work. Unfortunately due to the funding it is only

[ccp4bb] [off-topic] PhD position available

Dear all, A BBSRC funded PhD position is available in my laboratory in Exeter, focusing on enzymes for synthetic biology. The work is most likely going to be more enzymology than structural work, but please pass this on to any candidates who might be interested. Full details are available

[ccp4bb] Postdoc and PhD positions available in Exeter UK

Dear all, We have a 6 month postdoc position (covering parental leave) and a PhD studentship available in my laboratory at the Living Systems Institute in Exeter to investigate the biosynthesis of the O-antigen of Coxiella burnetii. Both positions would suit people with an interest in enzyme

[ccp4bb] PhD positions available

Hi everyone, I have three PhD opportunities available in my lab for students interested in structural biology. If you know anyone who might be interested please pass this message on to them! The Living Systems Institute where I am based has funded positions available in our PhD programme

Re: [ccp4bb] Enzyme Vmax and Km

Dear Prem, I agree entirely with Tristan's conclusion that the processed substrate is also acting as an inhibitor at higher concentrations. You would need to run an experiment with a wider range of concentrations used (especially lower concentrations) to get a better feel for the range of the

[ccp4bb] PhD position in Structural Biology, University of Exeter/Dstl

Dear all, My group at the Living Systems Institute in Exeter is seeking to appoint a PhD position on a four year studentship. This is an industrial partnership award with Dstl (UK). Unfortunately because of the conditions of the funding we can only consider UK nationals. The position will be

Re: [ccp4bb] Contagious, Self-Distributing "Vaccines?"

I'm afraid that the "Kent" variant is also mutating and is likely to pick up some of the more challenging mutations. There is already a version circulating with the E484 mutation that has a clear impact on the vaccine ("Bristol" variant), and another picked up in Scotland that has several

[ccp4bb] 4-year PhD position in Exeter, UK, in partnership with Syngenta

Dear all, We have a fully funded 4-year PhD position available in my group in Exeter, UK. The position will be using structural and enzymology techniques to study thiamine diphosphate-dependent enzymes. The project is a collaborative project with Syngenta in the UK. The position is open to

[ccp4bb] Reminder - PhD position in structural biology - closing 6th December

Dear Colleagues, Just a reminder that I am advertising a PhD position in structural studies of microbial enzymes in my laboratory for autumn 2022 start. The project is partnering with Syngenta, focusing on potential herbicide targets. Students will benefit from the opportunity of a placement

[ccp4bb] PhD position in time resolved crystallography

beyond the standard UK PhD stipend. Full details of the project are at https://www.exeter.ac.uk/study/funding/award/?id=4940, which has a link to the application site, and I'm happy to answer any questions by email. Kind regards, Nic Harmer Nicholas Harmer Associate Professor in Biochemistry

Re: [ccp4bb] open review?

Dear all, I'd agree with Frank's sentiment. There is a strong risk that it would put reviewers in a conflicted position. You only have to look at say the world of literature to see that authors very rarely say anything that isn't positive about another author's work publicly. As a grant

[ccp4bb] Postdoc and PDRA positions in enzyme cascades

Dear all, I have a 21 month postdoc position and a 3.5 year PhD position available in my lab at the Living Systems Institute in Exeter, UK. These would be suitable for someone looking for an exciting project building enzyme cascades to produce novel chemicals. The full adverts are linked to

Re: [ccp4bb] Unidentified electron density

Dear Sayan, It's a little hard to see from the images, but there seems to be continuous density to the aspartate indicating a covalent adduct. Perhaps it would be best to extract a crystal and run it through mass spec to get an exact mass on the adduct (and so its chemical formula)? Others who

[ccp4bb] Academic position openings in Exeter, UK

, and ESRF. We're very happy to speak informally to anyone interested! Kind regards, Nic Harmer Nicholas Harmer Associate Professor in Biochemistry University of Exeter Ext: 5179 www.exeter.ac.uk Living Systems Institute, Stocker Road, Exeter, EX4 4QD [Winner badge] [http://www.exeter.ac.uk/codebox