[ccp4bb] PhD studentship in the pioneering use of bovine knob domains for an antibody-assisted structure-based drug discovery approach targeting proteins involved in chronic inflammatory diseases

Dear all, There is a PhD studentship available in my lab at the Leicester Institute of Structural and Chemical Biology, University of Leicester, in partnership with the biopharmaceutical company, UCB. This position would be to start in October 2023 We will use an innovative antibody-assisted

Re: [ccp4bb] Non-standard amino acids in Coot

Dear Paul and Cheng, Thank you both for your suggestions to solve the issue, they were very informative. I had struggled to find the prepared dictionary for methyl cysteine, or at least my search terms were not appropriate! As it was, methyl cysteine was already listed in the database, which

[ccp4bb] Non-standard amino acids in Coot

Dear ccp4bb, I am having an issue with a non-standard amino acid in Coot. I have a cyclic peptide that is stapled using two cysteine residues and a methylene bridge. I have prepared a restraints file using ACEDRG for a methyl cysteine as a surrogate for one of the cysteine residues and I have