Dear All,
Thank you very much for valuable suggestions and educating me on the normal
mode refinement. Actually, I am trying to refine a protein (cytosolic
domain and trans-membrane domain). I found a solution through PHASER and
density looks really good in both domain but as i proceeds with
Dear All,
Thank you very much for valuable suggestions and educating me on the normal
mode refinement. Actually, I am trying to refine a protein (cytosolic
domain and trans-membrane domain). I found a solution through PHASER and
density looks really good in both domain but as i proceeds with
On Tuesday, 21 October 2014 07:39:53 AM Appu kumar wrote:
Dear All,
Thank you very much for valuable suggestions and educating me on the normal
mode refinement. Actually, I am trying to refine a protein (cytosolic
domain and trans-membrane domain). I found a solution through PHASER and
On Monday, 20 October, 2014 18:10:03 Appu kumar wrote:
Dear CCP4 Users,
I seek your valuable advice and suggestion in carrying out the normal mode
structure refinement which manifest the dynamics of protein as linear
combination of harmonic modes, used to describe the motion of protein
I agree with Ethan.
In philosophy, NMA is a useful analysis to study low frequency collective
motions. That is true by taking a stand-alone structure and explore such
motions of biological interest. Domain motions in the crystallographic
environment need not necessarily correspond to those
Hello,
You can also contact elNemo or NOMAD-Ref server developers about getting
covariance/correlation matrices from normal mode analysis outputs to know
the correctly coordinated mobile atoms. In this way you can compare with
biological data also. In Shekhar's said paper K. Suhre (one of the
