Re: [Felvtalk] Found some of original paper on therapy for felv
re-read it folks, the cats were NOT tested with the IFA as far as i can tell--just progressive SNAPs. they state that the IDEXX test is for ANTIGENS (exposure) as i keep emphasizing, so the fact that the cat is ultimately negative on a snap just proves what has actually been known for a long time: 70% of cats will NOT remain viremic! and the very fact that they consistently say HIV for a feline population tells me that they don't know their anal glands from their whiskers: HIV is specific to humans, FIV to cats. (what part of FELINE don't these people get?? ) i also seriously question the reversal of the FIV cats, as i've never seen or heard anything reliable in the literature about WESTERN-BLOT positive FIVs being able to throw off the virus once it's established (which is what the FIV part of the snap tests for, actual antibodies.) i'll send this on to joel for his review, where was this published, j? i can't believe it could have been in a peer-reviewed pub, or that HIV/FIV nomenclature would have been caught. thanks for sharing it, tho. MC -- Spay Neuter Your Neighbors! Maybe That'll Make The Difference MaryChristine Special-Needs Coordinator, Purebred Cat Breed Rescue (www.purebredcats.org) Member, SCAT (Special-Cat Action Team) ___ Felvtalk mailing list Felvtalk@felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org
Re: [Felvtalk] Found some of original paper on therapy for felv
trmckel...@charter.net wrote: Thank you for this information, could you provide a reference, so I could review the original work? I'd also like to strongly caution that even though something looks really good in a research article, it doesn't mean it is effective or even safe, especially when it involves animal testing for use in humans. First hand experience on this one. Thanks, Terry jbero tds.net jb...@tds.net wrote: = I did a little searching and found a more detailed paper on what was done with these few cats using antioxidant therapy and resulting change in viral status to negative. I copied and pasted it. EXAMPLES In vivo testing was performed to demonstrate the startling effectiveness of the treatment methods described herein. A series of laboratory tests were conducted on retrovirus-infected cats. In the preferred treatment regimen, the animal suffering from HIV(+), is administered relatively large doses of both water-soluble and fat-soluble antioxidants such as Vitamins C, A and E; an effective amount of at least one glutathione precursor such as N-acetyl cysteine; followed by an NFKB induction inhibitor such as one or more anti-inflammatory steroids or lazaroids. As summarized. in Table 4 below, seven cats heavily infected with HIV or FIV were treated according to the methods described and claimed herein. Each cat weighed approximately 10 to about 18 pounds. The cats were initially treated with a single dosage of an effective amount of an NFKB induction inhibitor, that is an anti-inflammatory steroid dose of DEPO-MEDROL (20-25 mg) and a series of oral dosages of a glutathione precursor, N-acetyl cysteine. The amount of N-acetyl cysteine administered with food to each cat was 1,200 mg per day. In addition, large dosages of fat-soluble and water-soluble antibxidants, Vitamins E, C, and A were administered to the cats orally every day by mixing in cat food. Vitamin E was administered at a dosage of 400 IU per day to each cat and Vitamin C was administered at a level of 500 mg per day to each cat. Vitamins A, K, and copper and zinc were also administered via 1 PET TABS per day to each cat. PET TABS is a commercially available multivitamin for pets such as cats, and is available from Smith-Kline Beecham. The treated cats: were monitored by ELISA assay for feline leukemia viruses antigen/feline immunodeficiency virus antibody test (CITE PRO COMBO: Programmed Biodetection available from IDEXX Corp. of Portland, Me.) for about two weeks. Of the seven cats tested, all seven appeared to have been cured from their earlier infection of feline leukemia, feline AIDS or both. The treatment process lasted one to two months of continual treatment with N-acetyl cysteine and high dosages of Vitamins C, E and A and periodic administration of anti-inflammatory steroids. TABLE 4 EFFECT OF ANTIRETROVIRAL THERAPY ON RETROVIRUS-INFECTED CATS Age Sex Name Assay Symptoms Assay 8 F Champagne FELV(+), hair loss, lost teeth FELV(-), FIV(+) FIV(-) 8 M Precious FELV(+), vomiting, dental FELV(-), FIV(+) problems FIV(-) 9 F Missy FELV(+), Bloody diarrhea, FELV(-), FIV(+) problems dental FIV(-) 11 M Sampson FIV(+) vomiting, gum red FIV(-) 8 M Josey FELV(+) teeth loss, no FELV(-)appetite, lungproblem 10 M Patch FIV(+) poor appetite, FIV(-)lethargy 12 M Bud FIV(+) weight loss, no FIV(-) appetite Notes 1) One cat with FELV(+)/FIV(+) died without the treatment as a control. 2) Treatments: Cats were injected intramuscularly with 20 mg DEPO-MEDROL (anti-inflammatory steroid) and dispensed with 1,200 mg powdered N-acetyl cysteine, 200 IU of Vitamin E, 500 mg of Vitamin C and one PET TAB/day. 3) It takes from 3 weeks to 6 weeks for the cats to turn retrovirus positive reaction to negative after the treatment. 4) The symptoms of Champagne, Precious, and Missy such as dental problems, bloody diarrhea, and loss of appetite completely subsided after the treatment with steroids/antioxidants. The symptoms of Sampson such as vomiting, gum disease, and loss of appetite completely reversed after the treatment. Josey's symptoms of lung problem, loss of appetite, and gum infection cleared up following the treatment. The cats were maintained on PET TABS following the treatment with steroid/antioxidants. 5) At the conclusion of the test all cats remained FIV or leukemia virus negative. 6) Blood was drawn for analysis from four of the cats treated (Sampson, Josey, Patch, and Bud). The analysis included cell cultures, mitogen stimulation, and polymerase chain reaction assay for the retrovirus. All tests indicated the cats were fully cured as none indicated any sign of the virus. These cat experiments are the first to demonstrate that AIDS can be cured in an in vivo model. Treatments were performed by a licensed veterinarian. The treatment methods were also performed by a second veterinarian. The second set of treatments were also successful. In an optional treatment
[Felvtalk] Found some of original paper on therapy for felv
I did a little searching and found a more detailed paper on what was done with these few cats using antioxidant therapy and resulting change in viral status to negative. I copied and pasted it. EXAMPLES In vivo testing was performed to demonstrate the startling effectiveness of the treatment methods described herein. A series of laboratory tests were conducted on retrovirus-infected cats. In the preferred treatment regimen, the animal suffering from HIV(+), is administered relatively large doses of both water-soluble and fat-soluble antioxidants such as Vitamins C, A and E; an effective amount of at least one glutathione precursor such as N-acetyl cysteine; followed by an NFKB induction inhibitor such as one or more anti-inflammatory steroids or lazaroids. As summarized. in Table 4 below, seven cats heavily infected with HIV or FIV were treated according to the methods described and claimed herein. Each cat weighed approximately 10 to about 18 pounds. The cats were initially treated with a single dosage of an effective amount of an NFKB induction inhibitor, that is an anti-inflammatory steroid dose of DEPO-MEDROL (20-25 mg) and a series of oral dosages of a glutathione precursor, N-acetyl cysteine. The amount of N-acetyl cysteine administered with food to each cat was 1,200 mg per day. In addition, large dosages of fat-soluble and water-soluble antibxidants, Vitamins E, C, and A were administered to the cats orally every day by mixing in cat food. Vitamin E was administered at a dosage of 400 IU per day to each cat and Vitamin C was administered at a level of 500 mg per day to each cat. Vitamins A, K, and copper and zinc were also administered via 1 PET TABS per day to each cat. PET TABS is a commercially available multivitamin for pets such as cats, and is available from Smith-Kline Beecham. The treated cats: were monitored by ELISA assay for feline leukemia viruses antigen/feline immunodeficiency virus antibody test (CITE PRO COMBO: Programmed Biodetection available from IDEXX Corp. of Portland, Me.) for about two weeks. Of the seven cats tested, all seven appeared to have been cured from their earlier infection of feline leukemia, feline AIDS or both. The treatment process lasted one to two months of continual treatment with N-acetyl cysteine and high dosages of Vitamins C, E and A and periodic administration of anti-inflammatory steroids. TABLE 4 EFFECT OF ANTIRETROVIRAL THERAPY ON RETROVIRUS-INFECTED CATS Age Sex Name Assay Symptoms Assay 8 F Champagne FELV(+), hair loss, lost teeth FELV(-), FIV(+) FIV(-) 8 M Precious FELV(+), vomiting, dental FELV(-), FIV(+) problems FIV(-) 9 F Missy FELV(+), Bloody diarrhea, FELV(-), FIV(+) problems dental FIV(-) 11 M Sampson FIV(+) vomiting, gum red FIV(-) 8 M Josey FELV(+) teeth loss, no FELV(-)appetite, lungproblem 10 M Patch FIV(+) poor appetite, FIV(-)lethargy 12 M Bud FIV(+) weight loss, no FIV(-) appetite Notes 1) One cat with FELV(+)/FIV(+) died without the treatment as a control. 2) Treatments: Cats were injected intramuscularly with 20 mg DEPO-MEDROL (anti-inflammatory steroid) and dispensed with 1,200 mg powdered N-acetyl cysteine, 200 IU of Vitamin E, 500 mg of Vitamin C and one PET TAB/day. 3) It takes from 3 weeks to 6 weeks for the cats to turn retrovirus positive reaction to negative after the treatment. 4) The symptoms of Champagne, Precious, and Missy such as dental problems, bloody diarrhea, and loss of appetite completely subsided after the treatment with steroids/antioxidants. The symptoms of Sampson such as vomiting, gum disease, and loss of appetite completely reversed after the treatment. Josey's symptoms of lung problem, loss of appetite, and gum infection cleared up following the treatment. The cats were maintained on PET TABS following the treatment with steroid/antioxidants. 5) At the conclusion of the test all cats remained FIV or leukemia virus negative. 6) Blood was drawn for analysis from four of the cats treated (Sampson, Josey, Patch, and Bud). The analysis included cell cultures, mitogen stimulation, and polymerase chain reaction assay for the retrovirus. All tests indicated the cats were fully cured as none indicated any sign of the virus. These cat experiments are the first to demonstrate that AIDS can be cured in an in vivo model. Treatments were performed by a licensed veterinarian. The treatment methods were also performed by a second veterinarian. The second set of treatments were also successful. In an optional treatment regimen, to be followed when the animal suffering from HIV(+), is exhibiting AIDS (that is, a T-lymphocyte or CD 4 lymphocyte count less than 100 cells/mm 3 ), relatively large doses of both water-soluble and fat-soluble antioxidants and an effective amount of at least one glutathione precursor such as N-acetyl cysteine are administered. Before an NFKB induction inhibitor is administered, the CD 4 (T-lymphocyte) count is increased to about 100 cells/mm 3 or
Re: [Felvtalk] Found some of original paper on therapy for felv
Thank you for this information, could you provide a reference, so I could review the original work? I'd also like to strongly caution that even though something looks really good in a research article, it doesn't mean it is effective or even safe, especially when it involves animal testing for use in humans. First hand experience on this one. Thanks, Terry jbero tds.net jb...@tds.net wrote: = I did a little searching and found a more detailed paper on what was done with these few cats using antioxidant therapy and resulting change in viral status to negative. I copied and pasted it. EXAMPLES In vivo testing was performed to demonstrate the startling effectiveness of the treatment methods described herein. A series of laboratory tests were conducted on retrovirus-infected cats. In the preferred treatment regimen, the animal suffering from HIV(+), is administered relatively large doses of both water-soluble and fat-soluble antioxidants such as Vitamins C, A and E; an effective amount of at least one glutathione precursor such as N-acetyl cysteine; followed by an NFKB induction inhibitor such as one or more anti-inflammatory steroids or lazaroids. As summarized. in Table 4 below, seven cats heavily infected with HIV or FIV were treated according to the methods described and claimed herein. Each cat weighed approximately 10 to about 18 pounds. The cats were initially treated with a single dosage of an effective amount of an NFKB induction inhibitor, that is an anti-inflammatory steroid dose of DEPO-MEDROL (20-25 mg) and a series of oral dosages of a glutathione precursor, N-acetyl cysteine. The amount of N-acetyl cysteine administered with food to each cat was 1,200 mg per day. In addition, large dosages of fat-soluble and water-soluble antibxidants, Vitamins E, C, and A were administered to the cats orally every day by mixing in cat food. Vitamin E was administered at a dosage of 400 IU per day to each cat and Vitamin C was administered at a level of 500 mg per day to each cat. Vitamins A, K, and copper and zinc were also administered via 1 PET TABS per day to each cat. PET TABS is a commercially available multivitamin for pets such as cats, and is available from Smith-Kline Beecham. The treated cats: were monitored by ELISA assay for feline leukemia viruses antigen/feline immunodeficiency virus antibody test (CITE PRO COMBO: Programmed Biodetection available from IDEXX Corp. of Portland, Me.) for about two weeks. Of the seven cats tested, all seven appeared to have been cured from their earlier infection of feline leukemia, feline AIDS or both. The treatment process lasted one to two months of continual treatment with N-acetyl cysteine and high dosages of Vitamins C, E and A and periodic administration of anti-inflammatory steroids. TABLE 4 EFFECT OF ANTIRETROVIRAL THERAPY ON RETROVIRUS-INFECTED CATS Age Sex Name Assay Symptoms Assay 8 F Champagne FELV(+), hair loss, lost teeth FELV(-), FIV(+) FIV(-) 8 M Precious FELV(+), vomiting, dental FELV(-), FIV(+) problems FIV(-) 9 F Missy FELV(+), Bloody diarrhea, FELV(-), FIV(+) problems dental FIV(-) 11 M Sampson FIV(+) vomiting, gum red FIV(-) 8 M Josey FELV(+) teeth loss, no FELV(-)appetite, lungproblem 10 M Patch FIV(+) poor appetite, FIV(-)lethargy 12 M Bud FIV(+) weight loss, no FIV(-) appetite Notes 1) One cat with FELV(+)/FIV(+) died without the treatment as a control. 2) Treatments: Cats were injected intramuscularly with 20 mg DEPO-MEDROL (anti-inflammatory steroid) and dispensed with 1,200 mg powdered N-acetyl cysteine, 200 IU of Vitamin E, 500 mg of Vitamin C and one PET TAB/day. 3) It takes from 3 weeks to 6 weeks for the cats to turn retrovirus positive reaction to negative after the treatment. 4) The symptoms of Champagne, Precious, and Missy such as dental problems, bloody diarrhea, and loss of appetite completely subsided after the treatment with steroids/antioxidants. The symptoms of Sampson such as vomiting, gum disease, and loss of appetite completely reversed after the treatment. Josey's symptoms of lung problem, loss of appetite, and gum infection cleared up following the treatment. The cats were maintained on PET TABS following the treatment with steroid/antioxidants. 5) At the conclusion of the test all cats remained FIV or leukemia virus negative. 6) Blood was drawn for analysis from four of the cats treated (Sampson, Josey, Patch, and Bud). The analysis included cell cultures, mitogen stimulation, and polymerase chain reaction assay for the retrovirus. All tests indicated the cats were fully cured as none indicated any sign of the virus. These cat experiments are the first to demonstrate that AIDS can be cured in an in vivo model. Treatments were performed by a licensed veterinarian. The treatment methods were also performed by a second veterinarian. The second set of treatments were also successful. In an optional treatment regimen, to be followed when the animal
Re: [Felvtalk] Found some of original paper on therapy for felv
The patent office website says the patent for this has been abandoned (they didn't pay the fee to keep it an active patent). What I find really strange about this is that if it is such an effective treatment - why did they abandon a patent that could make them a fortune? Gary -- From: jbero tds.net jb...@tds.net Sent: Saturday, April 17, 2010 11:08 AM To: felvtalk@felineleukemia.org Subject: [Felvtalk] Found some of original paper on therapy for felv I did a little searching and found a more detailed paper on what was done with these few cats using antioxidant therapy and resulting change in viral status to negative. I copied and pasted it. ___ Felvtalk mailing list Felvtalk@felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org
