Re: [Freesurfer] FDR correction for statistical maps in Freeview?

2021-02-23 Thread Douglas N. Greve
There is nothing interactive. You can use mri_fdr. It will compute the threshold, which you can then use in freeview. It will also do the thresholding for you. On 2/22/2021 9:25 AM, Hannah Eichhorn wrote: External Email - Use Caution Dear all, I am using glmfit to analyse changes

[Freesurfer] FDR correction for statistical maps in Freeview?

2021-02-22 Thread Hannah Eichhorn
External Email - Use Caution Dear all, I am using glmfit to analyse changes in cortical thickness, but I couldn't find a description on how to perform FDR correction with FreeSurfer. Is there a way to perform FDR correction of the statistical maps in Freeview, analogous to how

Re: [Freesurfer] fdr correction problem

2018-12-11 Thread Greve, Douglas N.,Ph.D.
do you mean that nothing survived threshold? That happens sometimes. On 12/10/18 8:03 AM, 1013364183 wrote: External Email - Use Caution Dear Bruce?? I have fdr correction for sig.mgh obtained by mri_glmfit, but the corrected graphs are all 0. Why is this, the instructions and the

[Freesurfer] fdr correction problem

2018-12-10 Thread 1013364183
External Email - Use Caution Dear Bruce?? I have fdr correction for sig.mgh obtained by mri_glmfit, but the corrected graphs are all 0. Why is this, the instructions and the running results are as follows: mri_fdr --fdr .05 --i lh2.gender_age.glmdir/group2/sig.mgh

[Freesurfer] fdr correction problem

2018-12-10 Thread 1013364183
External Email - Use Caution Dear Bruce?? I have fdr correction for sig.mgh obtained by mri_glmfit, but the corrected graphs are all 0. Why is this, the instructions and the running results are as follows: mri_fdr --fdr .05 --i lh2.gender_age.glmdir/group2/sig.mgh

Re: [Freesurfer] FDR correction

2018-11-19 Thread Greve, Douglas N.,Ph.D.
High p-values (i,e close to 1) mean non-significance. I don't know how to do a power analysis with FDR. On 11/19/18 1:16 PM, Laura Ferrero wrote: > External Email - Use Caution > > Hi, > I performed an statistical analysis comparing autism group with control group > using volume/area

[Freesurfer] FDR correction

2018-11-19 Thread Laura Ferrero
External Email - Use Caution Hi, I performed an statistical analysis comparing autism group with control group using volume/area and thickness measures. I found significant differences in some regions but they were not significant after FDR correction. The majority of p-values

Re: [Freesurfer] Fdr correction using command line

2016-10-12 Thread neuroimage analyst
Thank you for that clarification,Doug. VM On Oct 12, 2016 12:09 PM, "Douglas N Greve" wrote: > The sign depends on how you set up the contrast. If you are using an > FSGD file and have two classes A and B and a contrast [+1 -1], then > positive indicates A>B. The

Re: [Freesurfer] Fdr correction using command line

2016-10-12 Thread Douglas N Greve
The sign depends on how you set up the contrast. If you are using an FSGD file and have two classes A and B and a contrast [+1 -1], then positive indicates A>B. The F.mgh is the map of F values which are unsigned. The gamma.mgh file will have the contrast values themselves including sign. The

Re: [Freesurfer] Fdr correction using command line

2016-10-12 Thread neuroimage analyst
Thanks, Doug for the binary. A quick follow-up: what does the sign in either mri_glmfit-sim/mri_fdr indicate? When I open F.mgh, the values are only positive and p-values obtained from them has sign of +/-. My understanding is + indicates where mean_A>mean_B and vice versa. If for example, I am

Re: [Freesurfer] Fdr correction using command line

2016-10-12 Thread Douglas N Greve
try this binary https://gate.nmr.mgh.harvard.edu/safelinks/greve/mri_fdr On 10/07/2016 04:11 PM, neuroimage analyst wrote: > > Hi, > > I was wondering if there is a way to perform fdr correction using > command line in freesurfer without using matlab as mri_glmfit-sim only > does bonferroni

Re: [Freesurfer] Fdr correction using command line

2016-10-07 Thread neuroimage analyst
Hi again. I think I can obtain fdr maps by: mri_surfcluster --in sig.mgh --subject fsaverage --hemi lh --annot aparc --sign pos --o fdr_005_lh_pos.mgh --fdr 0.05 --cortex --mask mask.mgh Can anyone comment if the above command is right to generate a clusterwise fdr corrected p<0.05? Thanks

[Freesurfer] Fdr correction using command line

2016-10-07 Thread neuroimage analyst
Hi, I was wondering if there is a way to perform fdr correction using command line in freesurfer without using matlab as mri_glmfit-sim only does bonferroni ? Thanks Regards MV ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu

[Freesurfer] FDR correction

2016-01-06 Thread stdp82
Hi list, I would like to ask you a number of questions regarding the FDR which is performed following seed-based fcMRI using FS-FAST.1-In the previous mail you have suggested me to use mir_fdr command line (version 6.0). Because I have some problem with new version license (as reported in

Re: [Freesurfer] FDR correction

2016-01-06 Thread Douglas N Greve
On 01/06/2016 11:00 AM, std...@virgilio.it wrote: > Hi list, > > I would like to ask you a number of questions regarding the FDR which > is performed following seed-based fcMRI using FS-FAST. > 1-In the previous mail you have suggested me to use mir_fdr command > line (version 6.0). Because I

Re: [Freesurfer] FDR correction in Matlab

2014-05-29 Thread Knut J Bjuland
Hi help lme_mass_FDR and help /lme_mass_FDR2/ For help with input and output? Knut J On 05/26/2014 11:24 AM, Nandita Vijayakumar wrote: Hi FS team, I was wondering if you could help me with FDR correction for linear mixed models within Matlab. I have run FDR2 correction using the

[Freesurfer] FDR correction in Matlab

2014-05-26 Thread Nandita Vijayakumar
Hi FS team, I was wondering if you could help me with FDR correction for linear mixed models within Matlab. I have run FDR2 correction using the following command: *dvtx = lme_mass_FDR2(F_lhstats.pval,F_lhstats.sgn,lhcortex,0.05,0); *However, dvtx was empty, so I would like to try lme_mass_FDR

Re: [Freesurfer] FDR Correction of NHP Surface Data

2012-09-10 Thread Clark Fisher
Per Bruce's suggestion, I'm reposting this now. A synopsis: I'm looking for a way to correct painted statistical maps for multiple comparisons using Freesurfer's tools, without having segmentation or any .xfm files. Thanks, Clark On Aug 23, 2012, at 10:09 AM, Clark Fisher wrote: Hi

Re: [Freesurfer] FDR Correction of NHP Surface Data

2012-09-05 Thread Douglas N Greve
Hi Clark, I just made a modification to mri_binarize to make it take an FDR as input. It computes the threshold and binarizes the input based on the threshold. I've put a copy here: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/mri_binarize.linux Run it with --help to get more

Re: [Freesurfer] FDR Correction of NHP Surface Data

2012-09-03 Thread Bruce Fischl
Hi Clark sorry, the end of the summer has been a period when things slip through the cracks. I think what you want is possible without a talairach or aseg, but it will need to wait for Doug to get back. Can you repost at the end of next week? Bruce On Thu, 30 Aug 2012, Clark Fisher wrote:

Re: [Freesurfer] FDR Correction of NHP Surface Data

2012-09-03 Thread Clark Fisher
Hi Bruce, Will do. Thanks again. -Clark On Sep 3, 2012, at 2:33 PM, Bruce Fischl wrote: Hi Clark sorry, the end of the summer has been a period when things slip through the cracks. I think what you want is possible without a talairach or aseg, but it will need to wait for Doug to get

Re: [Freesurfer] FDR Correction of NHP Surface Data

2012-08-29 Thread Clark Fisher
Hi Sebastian, I think you are right, both about tksurfer thresholding and the correct interpretation of FDR. As you point out though, there is some value in having maps that show how relatively well different points on the surface fit your model. At the very least, is there any way to

Re: [Freesurfer] FDR Correction of NHP Surface Data

2012-08-29 Thread Michael Waskom
Hi Clark, If you're loading the data into Python anyway to use with PySurfer, Nipy seems to have some utilities to do an FDR correction (docshttp://nipy.sourceforge.net/nipy/stable/api/generated/nipy.algorithms.statistics.empirical_pvalue.html

Re: [Freesurfer] FDR Correction of NHP Surface Data

2012-08-29 Thread Clark Fisher
Thanks Michael, I'll look into Nipy's FDR tools. I actually started this thread asking for help getting mri_surfcluster running for my situation (I have no talraich .xfm and no segmentation for my monkeys). The silence on that topic suggest that it might not be possible, or it's at least not

Re: [Freesurfer] FDR Correction of NHP Surface Data

2012-08-28 Thread Clark Fisher
Ok, maybe I'm making this question too intricate. Here's the short version: How can I FDR correct painted surface significance maps when I have no talraich .xfm file and no cortical segmentation? Thanks again, Clark Hi Freesurfers, I have another monkey-specific question. I'd like to output

Re: [Freesurfer] FDR Correction of NHP Surface Data

2012-08-28 Thread Bruce Fischl
Hi Clark you shouldn't need either. Load your overlays then click the button to compute the FDR threshold in the tksurfer configure overlay interface. cheers Bruce On Tue, 28 Aug 2012, Clark Fisher wrote: Ok, maybe I'm making this question too intricate. Here's the short version: How can I

Re: [Freesurfer] FDR Correction of NHP Surface Data

2012-08-28 Thread Clark Fisher
Hi Bruce, Thanks. I actually have used this function of tksurfer, but am looking for a way to save the corrected maps, so that they could be manipulated by other tools (for instance, viewed by PySurfer). I recognize that this may not be an officially supported functionality, but is there

Re: [Freesurfer] FDR Correction of NHP Surface Data

2012-08-28 Thread Bruce Fischl
I'll leave that for Doug. Bruce On Tue, 28 Aug 2012, Clark Fisher wrote: Hi Bruce, Thanks. I actually have used this function of tksurfer, but am looking for a way to save the corrected maps, so that they could be manipulated by other tools (for instance, viewed by PySurfer). I recognize

Re: [Freesurfer] FDR Correction of NHP Surface Data

2012-08-28 Thread Sebastian Moeller
Hi Clark, On Aug 28, 2012, at 11:15 AM, Clark Fisher wrote: Hi Bruce, Thanks. I actually have used this function of tksurfer, but am looking for a way to save the corrected maps, so that they could be manipulated by other tools (for instance, viewed by PySurfer). Does it

[Freesurfer] FDR Correction of NHP Surface Data

2012-08-23 Thread Clark Fisher
Hi Freesurfers, I have another monkey-specific question. I'd like to output FDR-corrected signficance surface maps for my monkey data, or at least FDR-threshold the maps. It seems like mri_surfcluster might be one way to go about this however: 1) I don't have any .xfm files for my

Re: [Freesurfer] FDR correction in Qdec

2010-07-10 Thread Xiaojing Long
Now it works if I enter the FDR in the text box - press Enter - click on Set Using FDR Thank you so much. Best, Xiaojing 2010/7/9 Douglas N Greve gr...@nmr.mgh.harvard.edu That is strange. Can you change the FDR to something ridiculous like .5 and see if that changes things? Xiaojing

[Freesurfer] FDR correction in Qdec

2010-07-09 Thread Xiaojing Long
Hi, all, I have some questions about performing the FDR correction in Qdec. I ran recon-all on all my subjects, then ran the surface group analysis following the Qdec tutorial. There are 3 factors in the qdec.table.dat file: age, gender and diagnosis. In the Design tab of Qdec, I selected the

Re: [Freesurfer] FDR correction in Qdec

2010-07-09 Thread Douglas N Greve
That is strange. Can you change the FDR to something ridiculous like .5 and see if that changes things? Xiaojing Long wrote: Hi, all, I have some questions about performing the FDR correction in Qdec. I ran recon-all on all my subjects, then ran the surface group analysis following

Re: [Freesurfer] FDR correction in Qdec

2010-07-09 Thread Xiaojing Long
I tried that. Still no change. And I tried running Qdec on all of my datasets. The problem occurs on all of them. Xiaojing 2010/7/9 Douglas N Greve gr...@nmr.mgh.harvard.edu That is strange. Can you change the FDR to something ridiculous like .5 and see if that changes things?

Re: [Freesurfer] FDR correction in FS vs. SPM

2010-06-04 Thread Chris Filo Gorgolewski
Hi Jürgen, 2010/5/27 Jürgen Hänggi j.haen...@psychologie.uzh.ch: For SPM, it has been shown that the FDR procedure based on height threshold (FDRp) is not appropriate in the random Gaussian field theory framework (Chumbley et al., 2010; Chumbley and Friston, 2009, both published in

[Freesurfer] FDR correction in FS vs. SPM

2010-05-27 Thread Jürgen Hänggi
Dear FS experts One of our reviewers would like to know whether the FDR procedures as implemented in FS on one hand and as implemented in SPM on the other hand are comparable. In FS, I think FDR is based on the height threshold (FDRp) and it is outside of the random Gaussian field theory

Re: [Freesurfer] FDR correction (fwd)

2009-10-19 Thread Donna Dierker
...@nmr.mgh.harvard.edu Cc: Donna Dierker do...@brainvis.wustl.edu Subject: Re: [Freesurfer] FDR correction (fwd) Dear Doug, Great discussion! But I think it misses the point. Can you forward the following to the list? The Benjamini-Hochberg (BH) FDR procedure uses the inequality P(i

Re: [Freesurfer] FDR correction (fwd)

2009-10-19 Thread Douglas N Greve
. Thanks Tom! -- Forwarded message -- Date: Fri, 16 Oct 2009 23:11:09 +0100 From: Thomas Nichols t.e.nich...@warwick.ac.uk To: Doug Greve gr...@nmr.mgh.harvard.edu Cc: Donna Dierker do...@brainvis.wustl.edu Subject: Re: [Freesurfer] FDR correction (fwd) Dear Doug, Great

Re: [Freesurfer] FDR correction (fwd)

2009-10-19 Thread Donna Dierker
From: Thomas Nichols t.e.nich...@warwick.ac.uk To: Doug Greve gr...@nmr.mgh.harvard.edu Cc: Donna Dierker do...@brainvis.wustl.edu Subject: Re: [Freesurfer] FDR correction (fwd) Dear Doug, Great discussion! But I think it misses the point. Can you forward the following to the list

Re: [Freesurfer] FDR correction (fwd)

2009-10-19 Thread Douglas N Greve
-- Date: Fri, 16 Oct 2009 23:11:09 +0100 From: Thomas Nichols t.e.nich...@warwick.ac.uk To: Doug Greve gr...@nmr.mgh.harvard.edu Cc: Donna Dierker do...@brainvis.wustl.edu Subject: Re: [Freesurfer] FDR correction (fwd) Dear Doug, Great discussion! But I think it misses the point. Can you

Re: [Freesurfer] FDR correction

2009-10-17 Thread Anderson Winkler
Dear all, The BH procedure is dependent on the number of tests and, for neuroimaging methods, more tests is often equivalent to higher resolution, either in voxel-based or surface-based representations of the brain. The question that arises is whether this would influence sensitivity and/or

Re: [Freesurfer] FDR correction (fwd)

2009-10-17 Thread Doug Greve
...@nmr.mgh.harvard.edu Cc: Donna Dierker do...@brainvis.wustl.edu Subject: Re: [Freesurfer] FDR correction (fwd) Dear Doug, Great discussion! But I think it misses the point. Can you forward the following to the list? The Benjamini-Hochberg (BH) FDR procedure uses the inequality P(i) = i / V * q

[Freesurfer] FDR correction

2009-10-16 Thread Yulia WORBE
Dear Freesurfer team, We are currently doing a cortical thickness studies between a group of psychiatric patients (n=60) and controls (n=30). We tested several smoothing levels (15mm, 20mm, 25mm) When setting an uncorrected threshold (such as p0.005), we obtained several regions of

Re: [Freesurfer] FDR correction

2009-10-16 Thread Michael Harms
Your FDR analysis sounds correct. You probably have a rather small number of marginally significant vertices, which is why none survive FDR. You could try increasing the q value from say 0.05 to 0.1, in which case 10% of the surviving vertices would be expected to be false positives. cheers,

Re: [Freesurfer] FDR correction

2009-10-16 Thread Donna Dierker
I never heard anything on my post here, but it might just be high surface resolution: http://www.mail-archive.com/neuro-mult-c...@brainvis.wustl.edu/msg00026.html On 10/16/2009 09:58 AM, Michael Harms wrote: Your FDR analysis sounds correct. You probably have a rather small number of

Re: [Freesurfer] FDR correction

2009-10-16 Thread Michael Harms
Interesting post Donna, but my understanding of FDR is that it sets the p-value threshold based on the LARGEST p-value that satisfies the FDR relationship. That is, steps 3 and 4 in Genovese et al. (2002) are: 3) Let r be the largest i for which p = i/V*q (assuming c=1) 4) Threshold the image

Re: [Freesurfer] FDR correction

2009-10-16 Thread Donna Dierker
Regardless: FDR's sensitivity appears resolution-dependent to me. On 10/16/2009 10:39 AM, Michael Harms wrote: Interesting post Donna, but my understanding of FDR is that it sets the p-value threshold based on the LARGEST p-value that satisfies the FDR relationship. That is, steps 3 and 4

Re: [Freesurfer] FDR correction

2009-10-16 Thread Doug Greve
Good point (meaning that I don't know the answer). I'll see if I can find out. doug On Fri, 16 Oct 2009, Donna Dierker wrote: Regardless: FDR's sensitivity appears resolution-dependent to me. On 10/16/2009 10:39 AM, Michael Harms wrote: Interesting post Donna, but my understanding of

[Freesurfer] FDR correction

2009-03-24 Thread Lars M. Rimol
Hi, I have done an analysis involving three groups, so there are three pairwise comparisons across two hemispheres = 6 p-maps. I want to adjust for multiple comparisons (across the vertices), so I use FDR. But since FDR determines the threshold basd on the actual p-values, I get 6 different

Re: [Freesurfer] FDR correction

2009-03-24 Thread Pedro Paulo de Magalhães Oliveira Junior
Some links that may be helpful: http://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/QdecMultipleComparisons http://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/GroupAnalysis http://surfer.nmr.mgh.harvard.edu/fswiki/MultipleComparisons Hope it helps. PPJ

RE: [Freesurfer] FDR correction

2009-03-24 Thread Lars M. Rimol
Date: Tue, 24 Mar 2009 14:03:46 -0300 Subject: Re: [Freesurfer] FDR correction From: p...@netfilter.com.br To: lari...@gmail.com CC: freesurfer@nmr.mgh.harvard.edu Some links that may be helpful: http://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/QdecMultipleComparisons http

[Freesurfer] FDR correction

2008-08-27 Thread Manja Lehmann
Hi, We've noticed that FDR correction produces different p-values for the left and right hemispheres. We found that this issue was observed previously and an email was sent to the mailing list (see below), however, no answer was received. We wondered if anybody has noticed this problem

Re: [Freesurfer] FDR correction

2008-08-27 Thread Pedro Paulo de Magalhães Oliveira Junior
Manja, I think FDR can be different for each hemisphere since they are taken apart during processing. Best Regards, Pedro Paulo Jr 2008/8/27 Manja Lehmann [EMAIL PROTECTED] Hi, We've noticed that FDR correction produces different p-values for the left and right hemispheres. We found that