Dear nmusers:
Recently I am trying to build a cell-cycle based tumor growth model, i.e.
tumor size = G1+ S + G2 + M. Meanwhile, I have quite a few simultaneous
biomarkers to characterize the cycle behaviors. Those biomarkers could be
calculated based on the population of G1, S, G2, and M. I have
Dear Feng, a smart way could be to (actually) write down equations for the
other biomarkers.
The simplest way to do this is is to assume that when cells have evolved in
a given phase (say G1) for a particular duration, they move to the following
one (S). By doing such, you may also solve your
Feng,
There is no need to worry about compartment numbers to match your
observations. The CMT data item is only needed when you have to identify
a compartment for an AMT. With NONMEM VI it is no longer necessary to
use CMT and AMT to initialize compartments. If you are still using
NONMEM V
Feng, I don't really understand what you're trying to do , but, it might be helpful to note that you are not required to use the compartment prediction in the Y = statementFor example, if you have$DESDADT(1) = DADT(2) = DADT(3) = ...it is permitted to have$ERRORY = A(1)/6 + LOG(A(2)) +
