Hello there. I have been having some discussion with our pharmacists on whether or not patients who present to the ED in severe sepsis or septic shock should receive a full dose of an aminoglycoside (when indicated) within the first hour regardless of Cr clearance? The practice of our ED physicians thus far has been to order a full dose, and now we are getting some feedback from pharmacy to reduce the dose per renal function, which seems appropriate with consecutive doses along with monitoring drug levels. I am concerned about delaying administration. For initial empric therapy what are the rest of you doing in such cases? Any literature available for me to share with the pharmacy? Thank you!
Jessica Harkey, RN, BSN, CCRN Sepsis Program Coordinator San Joaquin Community Hospital 661-869-6874 [email protected]<mailto:[email protected]> [Description: wr]
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