Dana,
I hope this helps you:
v Lactic Acid >2 is Severe Sepsis associated with organ dysfunction, 
hypotension, or hypoperfusion abnormalities including:
*     Skin mottling or capillary refill time >3 seconds
*     Urine output < 0.5 ml/kg for at least 1 h or patient requiring renal 
replacement therapy
*     Serum lactate >2 mmol/L
*     Acute alteration of mentation or encephalopathic changes on 
electroencephalogram
*     Disseminated intravascular coagulation or platelets <100K cells/mL
*   Acute lung injury or acute respiratory distress syndrome
v Septic Shock is Severe Sepsis PLUS
v Hypotension despite adequate fluid resuscitation OR
v Serum Lactate > 4 mmol/L
  If you are just beginning to collect data you might focus on how your 
institution does in getting the 3 hour bundle in for the lactate >4. I think 
there needs to be more research done on implementing the 3 hours bundle when 
the lactic acid is 2......but from the sepsis expedition the experts stated 
these patients need fluid.....maybe not the entire 30ml/kg, but fluid and the 
other elements too.
There is a study that shows the faster you get the 3 hour bundle completed the 
better the outcomes. "Multicenter Implementation of Server Sepsis and Septic 
Shock Treatment Bundle" By Russell R. Miller III et, al
If I miss spoke please someone correct me.
Thank you,
Amy

Amy L. Sprague MSN, RN, ACNS-BC, CCRN
    Clinical Nurse Specialist~Critical Care
Franciscan St. Francis Health
8111 S. Emerson Avenue
Indianapolis, IN 46237
Office (317)528-6800
[email protected]
"People grow through experience if
they meet life honestly and courageously."
Eleanor Roosevelt,
U.S. first lady




From: [email protected] 
[mailto:[email protected]] On Behalf Of DanaMarie 
Smith
Sent: Friday, November 22, 2013 9:10 AM
To: [email protected]
Subject: [Sepsis Groups] Lactic Acid

Im sorry just one more question. For the Lactic Acid, I have been collecting if 
its >4 as criteria for severe sepsis but I have been seeing articles saying 
they are considering >2 as criteria for severe sepsis. So I guess my question 
is do I count Lactic Acid >2 as severe sepsis and the Lactic Acid >4 is for the 
6 hr bundle?
                                            Thank You,
                                                Dana

Dana Marie Smith RN
Clinical Data Analyst
Quality/Performance Improvement
Phone # 215- 612-5354
Fax # 215-612-4463



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