We are rolling out the qsofa on the acute care floors even as we speak  and 
data is forthcoming.  It may be available by 1st Q 2017.

Petra Grami, MSN, RN, CCRN, NE-BC, CVRN
Nurse Manager
Medical-Surgical ICU 7 South 3, Acute Care Dialysis, and Outpatient Apheresis
CHI St. Luke's Health
Baylor St. Luke's Medical Center
6720 Bertner Ave. | Houston, TX  77030
Office: 832-355-6735 | Fax 832-355-6739
[email protected]<mailto:[email protected]>
[cid:[email protected]]
StLukesHouston.Org<http://www.stlukeshouston.org/> | 
@StLukes_Houston<https://twitter.com/StLukes_Houston>




From: Sepsisgroups [mailto:[email protected]] On 
Behalf Of Jaehne, Anja Kathrina
Sent: Friday, September 30, 2016 12:09 PM
To: '[email protected]'
Subject: Re: [Sepsis Groups] SIRS+organ dysfunction vs. qSOFA/SOFA

CAUTION:This email is not from a CHI source. Only click links or open 
attachments you know are safe.


Please see below some retrospective comparisons regarding Emergency Department 
Triage assessments in concerns to qSOFA and SIRS criteria (August 2015- June 
2016). These values are only in consideration of Triage for q SOFA and SIRS for 
patients who are retrospectively clearly identified as having either severe 
sepsis or septic shock. I would not be able to comment on specificity or 
sensitivity in the larger undifferentiated ED patient population at triage.
TRIAGE ED qSOFA (Hypotension SBP< 100 mmHg; Respiratory Rate >/ = 22 breath/ 
min; Mental status changes)


qSOFA 0 or 1 at Triage

qSOFA 2 or 3 at Triage

All Patients

260/382 (68%)

122/382 (32 %)

Severe Sepsis Patients

150/192 (78%)

42/192 (22 %)

Septic Shock patients

110/190 (58 %)

80/190 (42 %)




The above data for our ED would mean, that if we would do a qSOFA assessment 
only once at triage and would base further clinical decisions on this, we may 
miss 58 - 78 % of patients with severe sepsis or septic shock. However qSOFA is 
not intended as singular assessment !
But I agree with what was said: it does not provide a sensitive initial 
screening assessment tool for the ED setting.
Especially the assessment of mental status changes in the ED setting appears to 
be difficult particular in patients who are new to the ED, have no family or on 
certain medications. The GCS is often normal even when other mental alterations 
may be present but not documented not even recognized in the ED setting! I can 
see that in the ICU setting it may be easier to recognize mental status changes 
in patients which are known to the treatment teams. This is often not possible 
in the ED!
TRIAGE ED SIRS (HR > 90 bpm, RR >/=20, Temp <36 C or > 38 C, WBC <4 or > 12 or 
bandemia >10)


0 or 1 SIRS

2 or more SIRS

All Patients

48/382 (13 %)

334/382 (87 %)

Severe Sepsis Patients

27/192 (14 %)

165/192 (86 %)

Septic Shock Patients

21/190 (11 %)

169/190 (89 %)


When we use TRIAGE SIRS criteria on the same patients who were assessed with 
qSOFA in the ED, and which have been later by chart review confirmed to have 
severe sepsis or septic shock, we are less likely to underestimate the 
potential risk of sepsis in these patients.

My five cents: The qSOFA may be a tool for the continued ICU screening for 
septic patients. It may be not such a good tool in the ED triage setting.  
>From our observational data it appears to me that SIRS criteria do exactly 
what Dr Bone had in mind: Identify patients with potential sepsis EARLY. SIRS 
criteria are not bulled proof, but they currently appear at ED triage the 
better initial tool to use to use when screening for patients at risk for 
severe sepsis or septic shock! Hopefully we will have further data soon to have 
a more prospective validation of qSOFA as a screening tool for sepsis in the ED!
Maybe qSOFA performs better in the ICU!? Anyone what to share their data?


Kathrina
Anja Kathrin Jaehne, MD
Clinical Research Coordinator
Department of Emergency Medicine
Henry Ford Hospital, Detroit MI 48202

[email protected]<mailto:[email protected]>

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