From: Reid Smith <[email protected]>
 To:   [email protected]
 Date: Mon, 13 Jul 1998
 Subj: interesting info - ATHEROSCLEROSIS

 Got high cholesterol maybe there is a reason!! 
 The body is retaining it to plug holes in the arterys.
 ===================================================================


                         ATHEROSCLEROSIS

                  How Cholesterol Plaque is Formed

 Until recently, the process of atherosclerosis had many unanswered
 questions: How is it that some people with high cholesterol levels
 never develop atherosclerosis? Why does one artery fill with
 cholesterol plaque while another remains free of disease?
 Fortunately, the latest clinical research has begun to lift the
 veil of mystery surrounding atherosclerosis. 

 Current studies indicate that atherosclerosis begins with a viral
 or bacterial infection (or other injury) of the artery. Recent
 reports point to an obscure germ called Chlamydia pneumoniae as the
 likely bacterial culprit. In fact, one study found that 79% of the
 specimens from patients undergoing coronary atherectomy (i.e., the
 removal of cholesterol plaque from diseased coronary arteries)
 tested positive for Chlamydia. 

 Once the artery is infected, the inner lining becomes inflamed --
 it swells and blisters, leaking enzymes and other chemicals into
 the blood stream. The body attempts to heal this damage by
 depositing cholesterol and a thin layer of congealed blood over the
 infected site. Unfortunately, once the infection has run its
 course, the body has no way to remove the cholesterol plaque that
 has built up. This is because the layer of congealed blood prevents
 chemical agents in the blood stream from reaching the cholesterol
 and re-dissolving it. 

 This scenario explains why a person's cholesterol level may be high
 and yet atherosclerosis doesn't form; the artery has to suffer
 viral or bacterial damage first, and then cholesterol is deposited. 

 Take Care 

 Reid





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