Bob, have you considered that all the medications that you are taking have side effects. One that certainly does, and is probably unnecessary is Lipitor. There is a front page article in Business Week this week about Lipitor. http://tinyurl.com/2fp4pc It definitely has many side effects. I took statins for many years, and quit when I started having strange pains. Then I found it does very little good for most people, but does great good for the companies that make it.
Gene

At 05:24 PM 1/22/2008, you wrote:
I have pain in my left ankle when it gets cold. I usually does not get cold during day at work. In evening sitting around in evening it gets cold and starts to hurt. I had a circulation test done it was good as a fact left leg was slightly better than right (go figure). I have arthritis, I had X-rays they show nothing. I take several Meds. Advair Diskus for my as ma, terazosin for blood pressure, triamterene/hctz cap, lipitor for cholesterol, tramadol hcl tab for arthritis and a 24 antihistamine (and nasal spray). I also take allergy shots on a regular basis and Venom shots as I am allergic to bees, wasps and hornets. I do use my nebulizer at least once a week with CS in it. This ancle pain is annoying, could it just be from the arthritis? I am open to ideas and solutions. I have a pair of thermal boot inserts I wear as slippers around the house and to bed. At night I can get away with just covering my left leg (with boot insert on) this keeps leg warm and stops pain. Even Motrin 800 do not stop the anchle from hurting. SICK LEAVE, Bob