Hi Steve, Malcolm, Doug and all,

I have been looking into a mushroom called Chaga lately which grows on birch trees primarily and in colder climates. It has a history of immune enhancement in Russia and has been used there to help in the recovery of cancer patients as well as as a preventative. Its properties can be better explained in the links below. I have read of several different ways to prepare it.

I am wondering if Chaga tincture could be made with DMSO to help achieve good penetration as one might do with herbs. Any thoughts anyone?

http://www.wholife.com/issues/9_4/03_article.html

http://www.survivaltopics.com/survival/the-chaga-natures-medicinal-mushroom/

http://www.sunfood.com/buy/1/34/Chaga-Extract-Mushroom-Science-90-veg-caps-Wild-Crafted-1433.aspx

http://www.raysahelian.com/chaga.html

http://www.rogersmushrooms.com/gallery/DisplayBlock~bid~5349~gid~~source~gallerydefault.asp

http://mushroom-collecting.com/mushroomchaga.html

http://www.mushroomharvest.com/catalog/product_info.php?cPath=36_39&products_id=161

http://www.optimallyorganic.com/Chaga.htm?gclid=CLv4nZPSmZ0CFZJM5Qodhlg_3A

http://www.premiumchaga.com/index.html

http://www.chagatrade.ru/

http://www.mychaga.com/default.aspx

http://www.mitobi.com/chaga.html

Blessings,

Peter


----- Original Message ----- From: "Malcolm" <[email protected]>
To: <[email protected]>
Sent: Friday, October 02, 2009 2:42 AM
Subject: RE: CS>DMSO and poke


Hi Steve;

There are a number of mushrooms that contain anti-viral compounds; most
of the research on this topic as well as other medicinal qualities of
fungi has been done in China or Japan.

Check out "Mycomedicinals" by Paul Stamets.

Available from Fungi Perfecti, P.O. Box 7634 Olympia, WA 98507
or go to:

http://www.fungi.com/

I'd also highly recommend his book "Mycelium Running"

Take care,
Malcolm


On Wed, 2009-09-30 at 18:30 -0500, Norton, Steve wrote:
Doug,

I certainly agree that pokeweed is interesting.
Both in it's unique antiviral properties: Three well-known different pokeweed antiviral protein (PAP)isoforms from the leaves of the pokeweed (PAP-I from spring leaves, PAPII from early summer leaves, and PAP-III from late summer leaves) that cause concentration-dependent depurination of genomic virus RNA. And there is the pokeweed mitogen. I have not come across mitogens in any other plant, although there may be some with mitogens. And in it's immune stimulating properties.

I have to admit that the roots worry me a little since they, along with any red parts of the plant (not including the berries), contains the highest amount of toxins. The berries are the lowest as long as you do not eat the seeds.

When I grew up in Kentucky, pokeweed would be found anywhere you did not cut or weed regularly. I have yet to see it in CA where I live now. I see that you offer pokeweed for sale or trade on your site. What are your prices for shoots, roots, leaves and berries and when are the seasons for each? I would like enough berries for a pie and some jelly to try. The rest would be for tincturing. Except for some shoots that I may cook if there are enough.

Thanks,
     Steve N

-----Original Message-----
From: polo [mailto:[email protected]]
Sent: Wednesday, September 30, 2009 2:57 PM
To: [email protected]
Subject: Re: CS>DMSO and poke

Steve,

I recommend a pure (upper 90s%) DMSO menstruum (herbal solvent), if you are planning on tincturing the fresh green herb. If you are tincturing dry herbs, I would go with the recommended ratios that are traditionally used and varies from herb to herb. For instance it is recommended that when you tincture dry poke root, you use a 50% ethanol/50% water solution, so I would likewise use a 50% DMSO/50% water solution. Just substitute the DMSO for ethanol.

DMSO should not need a preservative if used at the higher strengths, just like ethanol. Things usually do not grow in DMSO as they do not in ethanol, presuming the strength is high. I would not be afraid of herbal tinctures 30% or higher in DMSO concentrations. I mostly only use High purity DMSO in my tincturing process and I have yet to have a tincture spoil.

I have never tried to combine DMSO and ethanol as a combination menstruum. Interesting concept! I can only see an advantage to this from a solvent standpoint if both solvents can extract components of an herb, if one by itself could not. If you are only adding DMSO to provide a more efficient vehicle of herbal drug delivery, then yes, that might be an advantage too, though most people detest DMSO. You could extract the herb by either using a combined DMSO/ethanol menstruum or just tincturing each herb in a DMSO or ethanol menstruum then combining the two. Either way should be ok to my way of thinking.

The eclectic medical movement that specialized in botanical medicines from the late 1800s up till 1932 or so, found that the best poke root tincture was made directly from the fresh green poke root. The dry poke root is no where near as good or potent. The toxic qualities of poke weed are highly exaggerated. No doubt if you ate the mature weed like you would the young one or as you would any salad, you would suffer gastro-intestinal distress, but that's about it--puking. In some circles, it is felt that vomiting as a result of poke root is actually cathartic. This is held mainly by the puke & cleanse old time herbalists. I would not be worried about the widely publicized toxicity of poke. I know you will find that some young children in the long ago past were said to be poisoned by the berry. Maybe so. We don't know how much they ate, nor if they were compromised in some way or if younger systems are more susceptible. In the adult, poke berries were commonly used for arthritic conditions. As the old cliché goes, all things are poison in the right amounts and most poisons are medicinal in smaller amounts. Poke is no different. It is one of my favorite herbs and a superb anti-viral and lymphatic stimulant. It is great as a topical DMSO tincture.

doug


----- Original Message -----
> Doug,
> A little while back I asked you about making tinctures with DMSO
> (using the email address provided at your web site). If I remember
> right you recommended a 50% DMSO solution. Thanks for the info. I was
> wondering if you use a preservative in your DMSO tinctures? I am
> considering a DMSO/vodka tincture and wondered if you have tried
> something similar. If you do, would you need to combine the herb and
> DMSO  and let it set first before adding the vodka, to maximize
> bonding between DMSO and herb components rather than DMSO bonding with > alcohol?
> I also have a question regarding the tincturing of polkweed. The toxic
> components of pokeweed are water soluble. Should one dry and powder
> the pokeweed and then go through several soaking in water. Throwing
> away the water after each soaking before tincturing to eliminate the
> toxic substances? Or would you recommend an extraction using a non
> polar solvent to remove only the non water soluble components of the > pokeweed?
> Thanks,
>     Steve N


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