Hi Jimmy,

I run Sequest from Bioworks on our computer cluster, and then transfer
the files to the local machine running TPP, so yeas I had the c:/
Inetpub/wwwroot/ISB/data/AAS/test/
With the out-and dta- files in it.
I have attempted to run Sequest from TPP and I had the same problem;
the dta and out files are created, but the command indicates that is
still running. The problem occurs whether I send a few files or a
single one. But I have more than one file on the queue, the command
will not proceed to the next file. I can run Sequest from Bioworks on
the local machine without any problems.

On Jul 2, 6:55 pm, Jimmy Eng <[email protected]> wrote:
> Antonio,
>
> That warning about not being able to open the mzXML file is not
> indicative of the underlying problem.  It is truly just a warning and
> the analysis process is capable of finishing correctly even if the
> corresponding mzXML file is missing.
>
> The important question that's not clear from your description below is
> how did you run the Sequest search?  Did you run it separately via
> Bioworks or did you run the search through the TPP?  Although helpful
> but not required, it doesn't seem like you did the latter.  Do you have
> a directory (e.g. c:/Inetpub/wwwroot/ISB/data/AAS/test/) that has the
> Sequest .out files in it?
>
> - Jimmy
>
>
>
> Antonio wrote:
> > I have installed TPP v4.2 on windows XP. I have created the mzXML
> > datafiles from my Sequest search. Now I'm making the corresponding
> > pepXML files. I see that the first file is being created, it seems
> > that is finished but I see the following warming message at the end of
> > the “Output so far” field:
>
> > warning: cannot open mzXML file "c:/Inetpub/wwwroot/ISB/data/AAS/
> > test.mzXML" for reading MS instrument info and scan times.
> > And the command status window indicates that the command is still
> > running. Is it? I do not see the file increasing in size. I can open
> > the pepxml file, although IE indicates that there is an error on page.
> > It seems to me that the program is stuck and is not progressing to
> > next task: the creation of the next pepXML file. Solutions?
>
> > Thanks,
>
> >  Antonio- Hide quoted text -
>
> - Show quoted text -

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