Harry,

I made a modification to readmzXML for you that hopefully gets you the 
data in the format you want.  I'll send you a link to the binary offline.

- Jimmy

Harry wrote:
> Hello Brian,
> 
> I was able to generate a txt file from mzML or mzXML files using
> readmzXML. Thanks!
> 
> What I found curious was that the txt file generated from the mzML
> file does not contain the precursor ion list (which is necessary for
> interpreting the data), while the txt file generated from the mzXML
> file does have the precursor ion list.  The mzXML and mzML files being
> used were converted from the same RAW data using TTP.
> 
> I'd like to go back to my original question here again.  When I used
> the -b option (print brief peak list in interactive mode) with
> readmzXML, it showed peak intensities for each transitions of the
> specified SRM scan, on the screen.  This information is what I needed,
> besides those already in the txt file.  Is there a way to incorporate
> the SRM peak list into the txt file using readmzXML?
> 
> Thank you for your help!
> 
> Harry
> 
> On Aug 6, 2:19 pm, "Brian Pratt" <[email protected]> wrote:
>> Try passing it through readmzXML instead, you should be able to put the
>> result of that into Excel.
>>
>> -----Original Message-----
>> From: [email protected]
>>
>> [mailto:[email protected]] On Behalf Of Harry
>> Sent: Thursday, August 06, 2009 1:14 PM
>> To: spctools-discuss
>> Subject: [spctools-discuss] Re: A question on converting RAW data of MRM
>> experiments to mzXML
>>
>> Hello Matt, Thanks for replying to my question!
>>
>> I converted the my RAW date file to mzML, but had problems opening the
>> mzML file in Excel.  When I tried to open the file as an XML list, I
>> got the message: "There is a problem with the specified XML or schema
>> source". I clicked OK, then got another error message: "XML input
>> Error: some data failed to import".  In the end I got the spread sheet
>> with column heads, but no actual data.  I also tried to open the file
>> as a read-only workbook, again got an error message, even though this
>> time I can see part of the data appeared in the spread sheet.  When I
>> clicked OK on the error message, all was lost in the spread sheet.
>>
>> Could you enlighten me what might be the cause of this problem and how
>> to open the mzML files?
>>
>> P.S. you mentioned that mzML format stores SRM data in a chromatogram-
>> centric way, my data were collected using static infusion.  I wonder
>> if that would cause any problem.
>>
>> Thanks a lot,
>> Harry
>>
>> On Aug 6, 8:22 am, Matthew Chambers <[email protected]>
>> wrote:
>>> The m/z and intensity of each transition at each scan is stored in that
>>> scan's peak list in base64. So it's not human readable, but it's there.
>>> Incidentally, the mzML format stores SRM data in a chromatogram-centric
>>> way which is far more space and time efficient. Depending on what tool
>>> you're using to analyze the data you might try the new format.
>>> -Matt
>>> Harry wrote:
>>>> Hello group members!
>>>> I encountered a problem when using the data conversion function in the
>>>> TTP (v4.2 JETSTREAM rev 1, Build 200904071723) to convert my MRM
>>>> experimental data in .RAW format to mzXML.
>>>> In my MRM experiment setup, I had 3 transitions (i.e. 3 fragment ions)
>>>> for each precursor ion.  In the mzXML file that was converted from the
>>>> RAW data file, for each precursor ion, it showed the "base peak
>>>> intensity" and "total ion current",  which is the signal intensity of
>>>> the strongest transition and the sum of the signal intensity for all 3
>>>> transitions, respectively.  What is also very important for my
>>>> experiment, but missing in the mzXML file, is the signal intensity of
>>>> the weakest transition for each precursor ion.
>>>> So the question is: How can I get the individual signal intensity for
>>>> all 3 transitions of a precursor ion to show up in the mzXML file that
>>>> is converted from a RAW data file acquired in a MRM experiment?
>>>> Thanks so much for your help!
>>>> Harry
> 
> > 


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