Were all the wiff files acquired with the same version of Analyst? If 
not, that's probably the issue.

I recommend trying msconvert which reads WIFFs with a different API from 
mzWiff: instead of depending on the myriad of different Analyst 
versions, it uses the unified DLLs from Protein Pilot 3.0 (free trial 
version available). I've yet to find a non-corrupt WIFF file it doesn't 
work on.

http://sourceforge.net/projects/proteowizard/files/proteowizard/1.6.0/pwiz-1.6.0-tools-windows-i386.zip/download

-Matt


Sunghyouk Park wrote:
> Thanks for the information.
>
> The real problem is that a single computer generates working-mzXML 
> files for some wiff files but not-working files for other wiff files.
> (not only on different computers).
> For the empty scans, the working-mzxml file generated on a different 
> computer (for the same wiff file) does have a  non-zero peaksCount and 
> proper information for the particular scan.
>
> I want to import this mzXML file into mzmine but it reports errors for 
> the "corrupt peak" and refuses the import.
>
> Any suggestions will be appreciated.
>
> Sunghyouk
>
>
>
>
> On Fri, Sep 11, 2009 at 2:53 AM, Natalie Tasman 
> <[email protected] <mailto:[email protected]>> 
> wrote:
>
>     And by the way, the "AAAAAAAAAAA" string that you see is just the
>     encoding for an empty scan (as you've already seen, peaksCount
>     will be "0" for these scans.)
>
>     On Sep 10, 2009, at 10:45 AM, Brian Pratt wrote:
>
>>     I expect you'll find the difference between those computers is
>>     that they have different (or no) versions of the mass spec
>>     vendor's software installed.  The mzwiff program depends on the
>>     vendors DLLs to read their secret file format, and probably wants
>>     to see a certain version of that DLL.
>>
>>     On Thu, Sep 10, 2009 at 6:10 AM, Sunghyouk <[email protected]
>>     <mailto:[email protected]>> wrote:
>>
>>
>>         Dear mzwiff users
>>
>>         I was trying to convert ABI4000 *.wiff format file to mzXML using
>>         standalone mzwiff (v. 4.3.1).
>>         Strangely, it works for some files, but not for others.
>>         For the exactly same file, it gives working and not-working mzXML
>>         output files in different computers.
>>         The problem I found so far is that the not-working mzXML file
>>         has the
>>         following:
>>         In just a few scans out of thousands, some scan has
>>         "AAAAAAAAAAA" in
>>         the <peaks></peaks> block
>>         as shown below (right above the </scan> tag below)
>>
>>          <scan num="2857"
>>           msLevel="1"
>>           peaksCount="0"
>>           polarity="+"
>>           scanType="Q1 Scan"
>>           retentionTime="PT1728.74S"
>>           lowMz="0"
>>           highMz="0"
>>           basePeakMz="0"
>>           basePeakIntensity="0"
>>           totIonCurrent="0" >
>>           <peaks precision="32"
>>            byteOrder="network"
>>            contentType="m/z-int"
>>            compressionType="none"
>>            compressedLen="0" >AAAAAAAAAAA=</peaks>
>>          </scan>
>>
>>         In addition, most of the parameters are set to "0"
>>         (peaksCount, lowMz,
>>         etc)
>>
>>         Does anyone know how to fix this problem?
>>
>>         Thanks.
>>

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