Hi Matt,

I have just installed the trial version and already activated it and
rebooted the PC. But running msconvert still gives me the message
"[WiffFile::ctor] Reading ABI Wiff files requires Protein pilot 3.0 to
be installed. A trial version ......"

The wiff files were acquired on a QSTAR and I still have Analyst 1.1
installed on the PC. Any idea what's wrong?


Bernt

On Sep 11, 10:20 am, Matt Chambers <[email protected]>
wrote:
> Were all thewifffiles acquired with the same version of Analyst? If
> not, that's probably the issue.
>
> I recommend trying msconvert which reads WIFFs with a different API from
> mzWiff: instead of depending on the myriad of different Analyst
> versions, it uses the unified DLLs from Protein Pilot 3.0 (free trial
> version available). I've yet to find a non-corruptWIFFfile it doesn't
> work on.
>
> http://sourceforge.net/projects/proteowizard/files/proteowizard/1.6.0...
>
> -Matt
>
> Sunghyouk Park wrote:
> > Thanks for the information.
>
> > The real problem is that a single computer generates working-mzXML
> > files for somewifffiles but not-working files for otherwifffiles.
> > (not only on different computers).
> > For the empty scans, the working-mzxml file generated on a different
> > computer (for the samewifffile) does have a  non-zero peaksCount and
> > proper information for the particular scan.
>
> > I want to import this mzXML file into mzmine but it reports errors for
> > the "corrupt peak" and refuses the import.
>
> > Any suggestions will be appreciated.
>
> > Sunghyouk
>
> > On Fri, Sep 11, 2009 at 2:53 AM, Natalie Tasman
> > <[email protected] <mailto:[email protected]>>
> > wrote:
>
> >     And by the way, the "AAAAAAAAAAA" string that you see is just the
> >     encoding for an empty scan (as you've already seen, peaksCount
> >     will be "0" for these scans.)
>
> >     On Sep 10, 2009, at 10:45 AM, Brian Pratt wrote:
>
> >>     I expect you'll find the difference between those computers is
> >>     that they have different (or no) versions of the mass spec
> >>     vendor's software installed.  The mzwiff program depends on the
> >>     vendors DLLs to read their secret file format, and probably wants
> >>     to see a certain version of that DLL.
>
> >>     On Thu, Sep 10, 2009 at 6:10 AM, Sunghyouk <[email protected]
> >>     <mailto:[email protected]>> wrote:
>
> >>         Dear mzwiff users
>
> >>         I was trying to convert ABI4000 *.wiffformat file to mzXML using
> >>         standalone mzwiff (v. 4.3.1).
> >>         Strangely, it works for some files, but not for others.
> >>         For the exactly same file, it gives working and not-working mzXML
> >>         output files in different computers.
> >>         The problem I found so far is that the not-working mzXML file
> >>         has the
> >>         following:
> >>         In just a few scans out of thousands, some scan has
> >>         "AAAAAAAAAAA" in
> >>         the <peaks></peaks> block
> >>         as shown below (right above the </scan> tag below)
>
> >>          <scan num="2857"
> >>           msLevel="1"
> >>           peaksCount="0"
> >>           polarity="+"
> >>           scanType="Q1 Scan"
> >>           retentionTime="PT1728.74S"
> >>           lowMz="0"
> >>           highMz="0"
> >>           basePeakMz="0"
> >>           basePeakIntensity="0"
> >>           totIonCurrent="0" >
> >>           <peaks precision="32"
> >>            byteOrder="network"
> >>            contentType="m/z-int"
> >>            compressionType="none"
> >>            compressedLen="0" >AAAAAAAAAAA=</peaks>
> >>          </scan>
>
> >>         In addition, most of the parameters are set to "0"
> >>         (peaksCount, lowMz,
> >>         etc)
>
> >>         Does anyone know how to fix this problem?
>
> >>         Thanks.

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