Hello,

Anybody has experience using "Proteome Discoverer 1.0" software for SEQUEST
search. I use the Bioworks for SEQUEST search and new to "Proteome
Discoverer 1.0".  few of my concerns are as follows:

a) How to perform SEQUEST BATCH search using "Proteome Discoverer 1.0"? It
seems to accept only ine raw file at a time. Do you know how can one supply
multiple raw files for SEQEUST search?
b) The output is *.msf file which can be exported into protXML file format.
So does this mean "Proteome Discoverer 1.0" uses Protein Prophet algorithm
to identify significant proteins?
c) The SEQUEST search done through "Proteome Discoverer 1.0" doesnt seem to
output *.out files (or pepXML files). I am more interested in individual
peptide hits but dont see how one can get 1st and 2nd hit as we see in *.out
file using Bioworks).

I would really appreciate your feedback on this.

Thanks,
~Nikhil.

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