We'll chase this down.

Note for anyone else looking at these files, there's a typo in one of the
links on that page, actual links are
http://www.peptideatlas.org/repository/tmp/DP_Opti_Newpupi_mzML.tar.gz
http://www.peptideatlas.org/repository/tmp/DP_Opti_Newpupi_mzXML.tar.gz
http://www.peptideatlas.org/repository/tmp/DP_Opti_Newpupi_wiff.tar.gz

Brian

On Mon, Oct 5, 2009 at 9:52 AM, Zhi Sun <[email protected]> wrote:

>  Thanks Brian.  I just tried using the "peakPicking true [1,2]" to convert
> the file. It seems to produce the same error.
>
>
>
> Best,
>
> Zhi
>
>
>  ------------------------------
>
> *From:* [email protected] [mailto:
> [email protected]] *On Behalf Of *Brian Pratt
> *Sent:* Monday, October 05, 2009 9:41 AM
>
> *To:* [email protected]
> *Subject:* [spctools-discuss] Re: msconvert generated mzML file
>
>
>
> Well, I learned something today!  Sounds worth avoiding, though - msconvert
> is the coverter of choice moving forward. especially for mzML output.
>
>
>
> I'll have a quick look at the mzML and mzXML equivalent msconvert outputs
> from the X!Tandem point of view, since I'm the one that added that to
> X!Tandem.
>
>
>
> Brian
>
> On Mon, Oct 5, 2009 at 9:30 AM, Zhi Sun <[email protected]> wrote:
>
> Hi Brian,
>
>
>
> I have post the mzML, mzXML and also the wiff file to
> http://www.peptideatlas.org/repository/tmp/ if anyone is interested in
> taking a look.
>
>
>
> ReAdw have an option –mzML, it is “EXPERIMENTAL”.  The version I used was
> 4.3.0. I haven’t checked if there is a newer version out there.  I have
> checked with my colleague with the X!tandem version. He said the X!tandem
> version we use should be same as the one in currently released TPP.
>
>
>
> Thanks,
>
> Zhi
>  ------------------------------
>
> *From:* [email protected] [mailto:
> [email protected]] *On Behalf Of *Brian Pratt
> *Sent:* Monday, October 05, 2009 9:20 AM
>
>
> *To:* [email protected]
>
> *Subject:* [spctools-discuss] Re: msconvert generated mzML file
>
>
>
> I don't think Readw ever made mzML files did it?  Probably the user is
> thinking of mzXML there.
>
>
>
> X!Tandem's mzML reader is from the same library as msconvert's writer
> (assuming we're talking about the TPP build of X!Tandem), so a mismatch is
> unlikely.
>
>
>
> I think the problem probably isn't within the tools themselves, in this
> particular case, but in what data they're being fed.
>
>
>
> Brian
>
> On Fri, Oct 2, 2009 at 4:53 PM, Jimmy Eng <[email protected]> wrote:
>
>
> I'll be a translator.  Zhi seems to be having issues with ABI QQQ wiff
>  files.  They were translated to mzML using msconvert and X!Tandem
> didn't like them.  She mentioned ReAdW only to state that X!Tandem was
> able to process some unrelated mzML files in the past.
>
> The problem could be:
> 1) the QQQ file really has no good ms/ms spectra in it.
> 2) there's a problem with the QQQ to mzML conversion.
> 3) everything's fine with the data but for whatever reason X!Tandem
> can't handle the particular mzML correctly.
> 4) the X!Tandem spectral processing parameters are set weird.
>
> Even money on the first 3.
>
>
> On Fri, Oct 2, 2009 at 4:31 PM, Matthew Chambers
> <[email protected]> wrote:
> >
> > I'm lost. You said "recently I used the msconvert to convert some QQQ
> > wiff files to mzML format". Are we talking about ABI WIFF or Thermo RAW?
> >
> > -Matt
> >
> >
> > Brian Pratt wrote:
> >> You probably mean mzXML rather than mzML?
> >>
> >> On Fri, Oct 2, 2009 at 3:55 PM, Zhi Sun <[email protected]
> >> <mailto:[email protected]>> wrote:
> >>
> >>
> >>     I just mean the mzML format itself. I used ReAdw to convert RAW
> >>     file to mzML
> >>     format.
> >>
> >>     Thanks,
> >>     Zhi
> >>
> >>
> >>     -----Original Message-----
> >>     From: [email protected]
> >>     <mailto:[email protected]>
> >>     [mailto:[email protected]
> >>     <mailto:[email protected]>] On Behalf Of Matthew
> >>     Chambers
> >>     Sent: Friday, October 02, 2009 3:49 PM
> >>     To: [email protected]
> >>     <mailto:[email protected]>
> >>     Subject: [spctools-discuss] Re: msconvert generated mzML file
> >>
> >>
> >>     Hi Zhi,
> >>
> >>     You say it worked fine with ReAdW; do you mean mzWiff? If so, what
> >>     conversion settings did you use (for both msconvert and mzwiff)?
> >>
> >>     -Matt
> >>
> >>
> >>     Zhi Sun wrote:
> >>     > Hi All,
> >>     >
> >>     > Recently I used the msconvert to convert some QQQ wiff files to
> mzML
> >>     format,
> >>     > and did X!tandem search using those mzML files.  I ran into a
> >>     problem.
> >>     > X!tandem took really long time (2 or more hours) for loading the
> >>     spectra,
> >>     > and them after it finally finished loading, it just reported
> >>     "Loaded, No
> >>     > input spectra met the acceptance criteria." The X!tandem runs
> >>     fine on
> >>     other
> >>     > mzML file. I tested on one mzML which was generated by ReAdw
> before.
> >>     >
> >>     > When doing the conversion, I used default options for msconvert.
> >>     Does
> >>     anyone
> >>     > of you know what could be the reason for this? If necessary, I
> >>     could send
> >>     > the wiff file and also the mzML file.
> >>     >
> >>     > Thanks,
> >>     > Zhi
> >>
> >
> > >
> >
>
>
>
> <br
>
> >
>

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