It's impossible you had the same error you reported before:

>  I ran into a problem. X!tandem took really long time (2 or more hours) 
for loading the spectra,

Since it hasn't been two hours, I know it must be a new error. Or at 
least, it must have gotten to the error much faster. :)

Presumably the file is now much smaller?

-Matt


Zhi Sun wrote:
>
> Thanks Brian. I just tried using the "peakPicking true [1,2]" to 
> convert the file. It seems to produce the same error.
>
> Best,
>
> Zhi
>
> ------------------------------------------------------------------------
>
> *From:* [email protected] 
> [mailto:[email protected]] *On Behalf Of *Brian Pratt
> *Sent:* Monday, October 05, 2009 9:41 AM
> *To:* [email protected]
> *Subject:* [spctools-discuss] Re: msconvert generated mzML file
>
> Well, I learned something today! Sounds worth avoiding, though - 
> msconvert is the coverter of choice moving forward. especially for 
> mzML output.
>
> I'll have a quick look at the mzML and mzXML equivalent msconvert 
> outputs from the X!Tandem point of view, since I'm the one that added 
> that to X!Tandem.
>
> Brian
>
> On Mon, Oct 5, 2009 at 9:30 AM, Zhi Sun <[email protected] 
> <mailto:[email protected]>> wrote:
>
> Hi Brian,
>
> I have post the mzML, mzXML and also the wiff file to 
> http://www.peptideatlas.org/repository/tmp/ if anyone is interested in 
> taking a look.
>
> ReAdw have an option –mzML, it is “EXPERIMENTAL”. The version I used 
> was 4.3.0. I haven’t checked if there is a newer version out there. I 
> have checked with my colleague with the X!tandem version. He said the 
> X!tandem version we use should be same as the one in currently 
> released TPP.
>
> Thanks,
>
> Zhi
>
> ------------------------------------------------------------------------
>
> *From:* [email protected] 
> <mailto:[email protected]> 
> [mailto:[email protected] 
> <mailto:[email protected]>] *On Behalf Of *Brian Pratt
> *Sent:* Monday, October 05, 2009 9:20 AM
>
>
> *To:* [email protected] 
> <mailto:[email protected]>
>
> *Subject:* [spctools-discuss] Re: msconvert generated mzML file
>
> I don't think Readw ever made mzML files did it? Probably the user is 
> thinking of mzXML there.
>
> X!Tandem's mzML reader is from the same library as msconvert's writer 
> (assuming we're talking about the TPP build of X!Tandem), so a 
> mismatch is unlikely.
>
> I think the problem probably isn't within the tools themselves, in 
> this particular case, but in what data they're being fed.
>
> Brian
>
> On Fri, Oct 2, 2009 at 4:53 PM, Jimmy Eng <[email protected] 
> <mailto:[email protected]>> wrote:
>
>
> I'll be a translator. Zhi seems to be having issues with ABI QQQ wiff
> files. They were translated to mzML using msconvert and X!Tandem
> didn't like them. She mentioned ReAdW only to state that X!Tandem was
> able to process some unrelated mzML files in the past.
>
> The problem could be:
> 1) the QQQ file really has no good ms/ms spectra in it.
> 2) there's a problem with the QQQ to mzML conversion.
> 3) everything's fine with the data but for whatever reason X!Tandem
> can't handle the particular mzML correctly.
> 4) the X!Tandem spectral processing parameters are set weird.
>
> Even money on the first 3.
>
>
> On Fri, Oct 2, 2009 at 4:31 PM, Matthew Chambers
> <[email protected] 
> <mailto:[email protected]>> wrote:
> >
> > I'm lost. You said "recently I used the msconvert to convert some QQQ
> > wiff files to mzML format". Are we talking about ABI WIFF or Thermo RAW?
> >
> > -Matt
> >
> >
> > Brian Pratt wrote:
> >> You probably mean mzXML rather than mzML?
> >>
> >> On Fri, Oct 2, 2009 at 3:55 PM, Zhi Sun <[email protected] 
> <mailto:[email protected]>
> >> <mailto:[email protected] <mailto:[email protected]>>> 
> wrote:
> >>
> >>
> >> I just mean the mzML format itself. I used ReAdw to convert RAW
> >> file to mzML
> >> format.
> >>
> >> Thanks,
> >> Zhi
> >>
> >>
> >> -----Original Message-----
> >> From: [email protected] 
> <mailto:[email protected]>
> >> <mailto:[email protected] 
> <mailto:[email protected]>>
> >> [mailto:[email protected] 
> <mailto:[email protected]>
> >> <mailto:[email protected] 
> <mailto:[email protected]>>] On Behalf Of Matthew
> >> Chambers
> >> Sent: Friday, October 02, 2009 3:49 PM
> >> To: [email protected] 
> <mailto:[email protected]>
> >> <mailto:[email protected] 
> <mailto:[email protected]>>
> >> Subject: [spctools-discuss] Re: msconvert generated mzML file
> >>
> >>
> >> Hi Zhi,
> >>
> >> You say it worked fine with ReAdW; do you mean mzWiff? If so, what
> >> conversion settings did you use (for both msconvert and mzwiff)?
> >>
> >> -Matt
> >>
> >>
> >> Zhi Sun wrote:
> >> > Hi All,
> >> >
> >> > Recently I used the msconvert to convert some QQQ wiff files to mzML
> >> format,
> >> > and did X!tandem search using those mzML files. I ran into a
> >> problem.
> >> > X!tandem took really long time (2 or more hours) for loading the
> >> spectra,
> >> > and them after it finally finished loading, it just reported
> >> "Loaded, No
> >> > input spectra met the acceptance criteria." The X!tandem runs
> >> fine on
> >> other
> >> > mzML file. I tested on one mzML which was generated by ReAdw before.
> >> >
> >> > When doing the conversion, I used default options for msconvert.
> >> Does
> >> anyone
> >> > of you know what could be the reason for this? If necessary, I
> >> could send
> >> > the wiff file and also the mzML file.
> >> >
> >> > Thanks,
> >> > Zhi
> >>
> >
> > >
> >
>
>

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