Hi, we are using an Agilent MSD/TOF for metabolomics. For us, it is important to convert to CENTROID mzXML for further data processing, otherwise the files become extremely large.
Greetings, Robert On Feb 16, 2:52 pm, "bio.x2y" <[email protected]> wrote: > Hi, > > I independently used both Trapper (4.3.1) and Msconvert (pwiz 1.6.0) > to convert a 1.4Gb Agilent MassHunter ".d" file containing ~16000 > spectra to mzXML. > > Parameters: > $msconvert --mzXML --verbose large.d > $trapper --mzXML -v large.d large.mzXML > > Msconvert took 5hrs 38mins to complete, generating a 57Gb file. > Trapper took 1hr 26mins to complete, generating a 28Gb file. > > I can understand the differences in size, given the differences in > structure and precision. However, the time difference still appears > quite high. > > One interesting observation is that msconvert does not start writing > to the output file until 1hr 20min has elapsed. At that point, the > file begins filling and the progress messages start appearing in the > output. Trapper, on the other hand, starts filling the output file and > reporting progress immediately. > > I have seen this occur now for two runs on two different days, so I > don't think it's related to other activity on the machine. > > Perhaps msconvert is engaging in some preprocessing that isn't > strictly necessary, for Agilent ".d" files at least? > > Thanks, > bio.x2y -- You received this message because you are subscribed to the Google Groups "spctools-discuss" group. To post to this group, send email to [email protected]. To unsubscribe from this group, send email to [email protected]. For more options, visit this group at http://groups.google.com/group/spctools-discuss?hl=en.
