Let's move this to the proteowizard-support list. What version of msconvert? I fixed 64-bit file I/O for SHA1Calculator some time ago.
-Matt On 4/19/2011 2:29 PM, John Damask wrote:
Hi, We have a large RAW file from a Velos HCD run,>2.2 Gig. MSConvert throws an error when trying to convert to mzXML with peakPicking true [1,2] "Error writing run 1 in<file>: [SHA1Calculator] Error hashing file<file>" The file opens in XCalibur...so it doesn't appear to be corrupt. We've successfully processed RAW files up to 2 Gig using MSConvert on a Win 2003 32-bit Server. Have we hit some limit? Unfortunately, I can't share the file. Thanks, John
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