I would suggest you run these in separate directories maintaining the
same basename of your spectrum files, this way iProphet will be able
to recognized multiple searches of the same spectra.  Run xinteract on
each search combining all fractions from each search into a single
analysis at the PeptideProphet level. Something like:

cd sequest

xinteract Band*.pep.xml

cd xtandem

xinteract Band*.pep.xml

cd ../iprophet

InterProphetParser ../sequest/interact.pep.xml
../xtandem/interact.pep.xml interact.iprophet.pep.xml

Write back if you need further clarification.

-David




On Wed, Aug 3, 2011 at 3:06 PM, Kinfai Au <[email protected]> wrote:
> Hi,
> I have a data with 8 factions. I searched them in SEQUEST and X!tandem
> respectively. The output files after PeptideProphet are:
>
> Band1.sequest.pep.xml
> Band2.sequest.pep.xml
> Band3.sequest.pep.xml
> Band4.sequest.pep.xml
> Band5.sequest.pep.xml
> Band6.sequest.pep.xml
> Band7.sequest.pep.xml
> Band8.sequest.pep.xml
>
> Band1.xtandem.pep.xml
> Band2.xtandem.pep.xml
> Band3.xtandem.pep.xml
> Band4.xtandem.pep.xml
> Band5.xtandem.pep.xml
> Band6.xtandem.pep.xml
> Band7.xtandem.pep.xml
> Band8.xtandem.pep.xml
>
> How can I merge them in InterProphet? I asked this question in the
> workshop. I work on Linux. Could you write me an example of the
> command line that I should use?
>
> Yours,
> Kinfai
>
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