Hi all,

In the ProteinProphet ProtXML viewer, one can see for each identified
protein the number of unique peptides.
See example here: http://161.116.29.106/tpp-bin/protxml_help.png

In this example, there are 7 unique peptides. But actually one can see
these peptides are variations of precursor charge states and post-
translational modifications of only 3 peptide sequences.
I therefore understand that in this context, "unique peptides" should
be understoof as "peptides with a different precursor ion".

However the MCP guidelines recommend that "multiple matches to
peptides with the same primary sequence should be counted as a single
distinct peptide, including multiple matches that represent different
precursor charge states or modification states".

My question is therefore: is there a way to automatically extract from
the TPP results the number of unique peptides per proteins, as defined
by the MCP guidelines?

Thanks in advance for your comments or tips.

Nicolas

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