Thanks! I will try to figure out if I have a naming problem, as I tried
putting mzXML file into same folder, now will look in detail according to
your instruction.
Thanks!
R

On Thu, Feb 9, 2012 at 1:24 PM, Luis Mendoza <
[email protected]> wrote:

> Hi Ruby,
> You are correct: the quantitation tools need to have access to the raw
> (mzXML) data to extract the chromatograms from the MS1 scans.  The
> name of the mz(X)ML files should match what is contained in the
> base_name attribute of the msms_run_summary tag in the pepXML file
> that you are analyzing -- this is typically in the same directory,
> though it is not necessary.
>
> Cheers,
> --Luis
>
>
> On Wed, Feb 8, 2012 at 8:48 AM, Ruby <[email protected]> wrote:
> > I'm running the TPP via Petunia. Our Sequest cluster cannot currently
> > be accessed via the TPP, so I currently convert .RAW to mzXML via
> > MSConvert, then search on the cluster. I take the Sequest search
> > results and copy them into TPP data folder and process them. This has
> > worked well for me for non-quant data. However, I have tried doing
> > this now with SILAC data, where I see peptides of both heavy and light
> > versions, and ASAPratio tells me
> > ". . . importing ASAPRatio protein ratios . . . and pvalues . . . Not
> > enough data for Gaussian fitting.
> > no pvalues available for this dataset"
> >
> > I'm wondering if ASAPratio requires more than just the Sequest search
> > results, but also the mzMXL file or something else - as I'm guessing
> > it can't get chromatographic info from sequest output? If it needs to
> > have another file type also, will it work if I place it in the same
> > folder in the TPP data directory as I place the search results?
> > Thanks!
> > Ruby
> >
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