Hi everyone,

We are using TPP to analyze data from 14N/15N Orbi-derived mass spectra 
(peptide extracts from trypsin digested gel slices).
At the “Analyze Peptides” step, the command fails for some 15N pepxml 
files. With the corresponding 14N files the command works fine.
Do you have any idea what the problem may be?

Below is the complete output from the TPP analysis command failure

Thanks a lot in advance!

Michaela


c:\Inetpub\tpp-bin\xinteract (TPP v4.6 OCCUPY rev 0, Build 201208170820 (MinGW))

 

running: "C:/Inetpub/tpp-bin/InteractParser "15N_slice03_interact.pep.xml" 
"hoc_protein_turnover_pnd28_03.xml" -L"7""

 file 1: hoc_protein_turnover_pnd28_03.xml

 processed altogether 8636 results

 

 

 results written to file 
c:/Inetpub/wwwroot/ISB/data/tpp_data/hoc/12112012/15N_pepxml/15N_slice03_interact.pep.xml

 

 direct your browser to 
http://pcj43/ISB/data/tpp_data/hoc/12112012/15N_pepxml/15N_slice03_interact.pep.shtml

 

 

 

command completed in 5 sec 

 

running: "C:/Inetpub/tpp-bin/DatabaseParser "15N_slice03_interact.pep.xml""

command completed in 0 sec 

 

running: "C:/Inetpub/tpp-bin/RefreshParser "15N_slice03_interact.pep.xml" 
"O:/hoc/12112012/database/decoy_uniprot_mouse(180210).fasta""

  - Searching the tree...error: could not open database file 
"o:/hoc/12112012/database/decoy_uniprot_mouse(180210).fasta" (No such file or 
directory)

  - Building Commentz-Walter keyword tree...

command "C:/Inetpub/tpp-bin/RefreshParser "15N_slice03_interact.pep.xml" 
"O:/hoc/12112012/database/decoy_uniprot_mouse(180210).fasta"" failed: Unknown 
error

 

command "C:/Inetpub/tpp-bin/RefreshParser "15N_slice03_interact.pep.xml" 
"O:/hoc/12112012/database/decoy_uniprot_mouse(180210).fasta"" exited with 
non-zero exit code: -1

QUIT - the job is incomplete

 

command "c:\Inetpub\tpp-bin\xinteract -N15N_slice03_interact.pep.xml -p0.05 -l7 
-O -dREV: hoc_protein_turnover_pnd28_03.xml" failed: Unknown error

 

 

*Command FAILED*
RETURN CODE:65280

 

 

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