I found the  msconvert of proteowizard is very convenient. 
It comes with vendor reader, so I don't need to install xcalibur.

http://proteowizard.sourceforge.net/downloads.shtml 


Maybe you can convert the RAW file to mzML before using TPP.


On Friday, November 23, 2012 11:07:39 PM UTC+8, Alex wrote:
>
> Hi there,
>
> I just downloaded the latest TPP 4.6.1and try to convert some RAW files to 
> mzML. It worked fine before I updated to this version. I get the following 
> error, any help?
> *
>
>
> EXECUTING: c:\Inetpub\tpp-bin\msconvert 
> c:/Inetpub/wwwroot/ISB/data/121119YEAST/2DYeast01.raw -v --mzML -o 
> c:/Inetpub/wwwroot/ISB/data/121119YEAST *
>
> *Command FAILED*
> RETURN CODE:13568
>

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