Hi Honglan,

I am on vacation this week. I did fix another processing issue with MSGF+
earlier, but I was still testing.  I will get back to you once I'm back
next week.

David
On Apr 13, 2016 12:14 AM, "Honglan Li" <[email protected]> wrote:

> Hi David
>
> It's me again.
>
> Thanks for giving me new PeptideProphet file to run MS_GF+ results.
>
> But it still has problem to execute new test file.
>
> Would you please tell me the reason?
>
>
> Thanks a lot.
>
> Honglan Li
>
>
> XML file:
> https://drive.google.com/file/d/0B5i2NDdAgrJ3bDY4ZFR0M2VOUlU/view?usp=sharing
>
> Recieved msg:
>
> ----
> KDModel.cpp, Line 144
> Expression: idx < posprobs_ -> size()
>
> This application has requested the Runtime to terminate it in an unusual
> way.
> Please contact the application's support team for more information
> ----
>
> Thanks a lot.
>
> Honglan Li
>
>
> 2016년 3월 30일 수요일 오후 8시 30분 5초 UTC+9, Honglan Li 님의 말:
>>
>>
>> Hi David.
>>
>> It's me again.
>>
>> Last time, you gave me the s/w and cmd.
>>
>> It's works well when I use the sample I gave you, and some other XML
>> files.
>>
>> But for some XML files, it still do not work well.
>>
>>                   XML file:
>> https://drive.google.com/file/d/0B5i2NDdAgrJ3bDY4ZFR0M2VOUlU/view?usp=sharing
>>
>>
>> When I executed this test sample (test2.pep.xml.xml) with the cmd you
>> told me
>>
>>                 "PeptideProphetParser.exe test2.pep.xml.xml NONPARAM
>> DECOY=XXX DECOYPROBS MINPROB=0 CLEVEL=2 ACCMASS PPM"
>>
>> I received msg as follows: (detail: I added captured error msg file)
>>
>> ----
>> KDModel.cpp, Line 144
>> Expression: idx < posprobs_ -> size()
>>
>> This application has requested the Runtime to terminate it in an unusual
>> way.
>> Please contact the application's support team for more information
>> ----
>>
>> Would you please tell me what happened to this XML file?
>>
>> Thanks a lot.
>>
>> Honglan Li
>>
>>
>>
>> 2016년 3월 28일 월요일 오전 8시 52분 13초 UTC+9, Honglan Li 님의 말:
>>>
>>> Thank you very much for your help, David.
>>>
>>> It works well now.
>>>
>>> Best wishes,
>>> Honglan Li
>>>
>>>
>>> 2016년 3월 26일 토요일 오전 2시 33분 59초 UTC+9, David Shteynberg 님의 말:
>>>>
>>>> Hello Honglan,
>>>>
>>>> I was unable to replicate the error on my system, however, I have
>>>> tested that this command works on a more recently compiled version of
>>>> PeptideProphet.  You can download the binary here
>>>> https://dl.dropboxusercontent.com/u/21286225/PeptideProphetParser.exe
>>>> and run as follows
>>>>
>>>> PeptideProphetParser.exe test.pep.xml NONPARAM DECOY=XXX DECOYPROBS
>>>> MINPROB=0 CLEVEL=2 ACCMASS PPM
>>>>
>>>>
>>>> I had to set a fairly high CLEVEL value on this data since MSGF+
>>>> suffers from scoring highly of some decoys and is not always accurate at
>>>> the critical 1% error.  The WARNING message in the new code has been
>>>> updated to reflect this problem.
>>>>
>>>> Cheers,
>>>> -David
>>>>
>>>>
>>>> On Thu, Mar 24, 2016 at 8:21 PM, Honglan Li <[email protected]> wrote:
>>>>
>>>>> Thanks for your quick reply.
>>>>>>
>>>>>
>>>>>    I tried the command you told me, but it stll didn't work well.
>>>>>
>>>>>    The warning msg is "*The discriminant function for MSGFPL is not
>>>>> yet complete" *
>>>>>
>>>>>    How to fix it ?
>>>>>
>>>>>
>>>>>   *cmd*:
>>>>>
>>>>>   xinteract -OPd -p0 -dXXX_ *.xml
>>>>>
>>>>>
>>>>>
>>>>>  *Error msg I received*
>>>>>
>>>>>   ----
>>>>> running: "/usr/local/tpp/bin/DatabaseParser 'interact.pep.xml'"
>>>>> command completed in 0 sec
>>>>>
>>>>> running: "/usr/local/tpp/bin/RefreshParser 'interact.pep.xml'
>>>>> 'C:\Users\JONGHUN\Desktop\MSGFPlus\C-25fmol\C-25fmol-R1\1.
>>>>> CYH\uniprot_C+H+Y+48.revCat.fasta'"
>>>>>   - Building Commentz-Walter keyword tree...  - Searching the
>>>>> tree...opening "C:\Users\JONGHUN\Desktop\MSGFPlus\C-25fmol\C-25fmol-R1\1.
>>>>> CYH\uniprot_C+H+Y+48.revCat.fasta" as
>>>>> "/home/mllab/hllee/uniprot_C+H+Y+48.revCat.fasta"
>>>>>
>>>>>   - Linking duplicate entries...  - Printing results...
>>>>>
>>>>> command completed in 11 sec
>>>>>
>>>>> running: "/usr/local/tpp/bin/PeptideProphetParser 'interact.pep.xml'
>>>>> NONPARAM DECOYPROBS MINPROB=0 DECOY=XXX_"
>>>>> Using Decoy Label "XXX_".
>>>>> Decoy Probabilities will be reported.
>>>>> Using non-parametric distributions
>>>>>  (MS-GF+) (minprob 0)
>>>>> WARNING!! *The discriminant function for MSGFPL is not yet complete.*
>>>>>  It is presented here to help facilitate trial and discussion.  Reliance 
>>>>> on
>>>>> this code for publishable scientific results is not recommended.
>>>>> init with MS-GF+ trypsin
>>>>> Segmentation fault (core dumped)
>>>>>
>>>>> command "/usr/local/tpp/bin/PeptideProphetParser 'interact.pep.xml'
>>>>> NONPARAM DECOYPROBS MINPROB=0 DECOY=XXX_" exited with non-zero exit code:
>>>>> 35584
>>>>> QUIT - the job is incomplete
>>>>>
>>>>> -----
>>>>>
>>>>> *XML format per PSM: (file: *
>>>>> https://drive.google.com/file/d/0B5i2NDdAgrJ3Y2diWDAzVHBQSm8/view?usp=sharing
>>>>> )
>>>>>
>>>>>   <spectrum_query
>>>>> spectrum="C:\Users\JONGHUN\Desktop\MSGFPlus\C-25fmol\C-25fmol-R1\1.
>>>>> CYH\C-25fmol-R1_QEx2_000090.51174.51174.4" spectrumNativeID="index=51174"
>>>>> start_scan="51174" end_scan="51174"
>>>>> precursor_neutral_mass="3972.990669523105" assumed_charge="4" index="1">
>>>>>       <search_result>
>>>>>         <search_hit hit_rank="1"
>>>>> peptide="VGNVGEDDAIPEVSHAGDVSTTLQVVNELLKDETVAPR" peptide_prev_aa="R"
>>>>> peptide_next_aa="F" protein="sp|P16521|EF3A_YEAST" num_tot_proteins="1"
>>>>> calc_neutral_pep_mass="3972.99140194498" massdiff="7.32421875e-04"
>>>>> protein_descr="sp|P16521|EF3A_YEAST Elongation factor 3A OS=Saccharomyces
>>>>> cerevisiae (strain ATCC 204508 / S288c) GN=YEF3 PE=1 SV=4" 
>>>>> num_tol_term="2"
>>>>> num_missed_cleavages="1">
>>>>>           <search_score name="raw" value="269"/>
>>>>>           <search_score name="denovo" value="289"/>
>>>>>           <search_score name="SpecEValue"
>>>>> value="2.8337685502588284E-39"/>
>>>>>           <search_score name="EValue" value="1.2856572993111488E-31"/>
>>>>>           <search_score name="IsotopeError" value="0"/>
>>>>>         </search_hit>
>>>>>       </search_result>
>>>>>     </spectrum_query>
>>>>>
>>>>>
>>>>>
>>>>>
>>>>>
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>>>>
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