Hi Luis,

Oh good to hear that it is already solved. If I could have a windows binary 
would be really useful.

Thanks.

Cheers,

Alejandro

On Tuesday, November 21, 2017 at 8:06:25 PM UTC+1, Luis wrote:
>
> Hi Alejandro,
>
> The misreported intensity ratios was a bug when using the -L or -H options 
> in XPRESS.  We have fixed this, as well as added support for those fields 
> in PepXMLViewer and Petunia.  If you are building from sources, simply 
> build revision 7683, or let us know if you would like Windows binaries.  
> This will also be in the next official release of TPP.
>
> Thanks for reporting this, and for the positive feedback on 5.1!
> --Luis
>
>
> On Sun, Nov 19, 2017 at 11:36 AM, Alejandro <[email protected] 
> <javascript:>> wrote:
>
>> Hi Luis,
>>
>> Yes, I would be really interested in testing it out as soon as you have a 
>> pre-release!
>>
>> I haven't checked if thats also the case with an older version, I should 
>> have a computer running 4.8. I will check it out and see.
>>
>> Thanks for the info on the tag, I will try to then find the mod tag.
>>
>> BTW, great release with the 5.1, so far I have found it quite good to 
>> work with.
>>
>> Cheers,
>>
>> Alejandro
>>
>> On Saturday, November 18, 2017 at 4:07:04 AM UTC+1, Luis wrote:
>>>
>>> Hello Alejandro,
>>>
>>> We will add these columns to the PepXMLViewer for the next release; I 
>>> can let you know when we have a pre-release version if you would be 
>>> interested in testing it.
>>>
>>> I am not sure why the ratios are not being correctly calculated; we will 
>>> have a look and try to fix as well for the next release.  Did you also have 
>>> trouble with this feature with the previous version of TPP?
>>>
>>> As you noted, modified peptide masses are rounded when reported in the 
>>> modified_peptide attribute of protXML in order save space and for making 
>>> the display simpler.  You can find the full modification masses within the 
>>> mod_aminoacid_mas tags within modification_info.  Or just round the pepXML 
>>> masses when comparing peptides.
>>>
>>> Cheers,
>>> --Luis
>>>
>>>
>>>
>>> On Thu, Nov 16, 2017 at 6:04 AM, Alejandro <[email protected]> wrote:
>>>
>>>> Dear all,
>>>>
>>>> I have been running since a while the 5.1 release candidate and since a 
>>>> week or so the new 5.1 release with great success thanks! 
>>>>
>>>> Lately I have been running more the TPP tools from the command-line and 
>>>> came across the option in XPRESS to export intensities as well as 
>>>> intensity 
>>>> based ratios of labeled type of data. I have used it but I don't see the 
>>>> option in Petunia in the Pepxml viewer to add it to the table. By manual 
>>>> inspection of the Pepxml, file I see them reported within the xpress tag, 
>>>> although the ratio is always reported as 0.000, even though the 
>>>> intensities 
>>>> are reported, and by manually calculating in some peptides it seems quite 
>>>> close to the ratio calculated from the areas, as expected. Is there an 
>>>> option to parse those out when exporting the tsv file? Moreover have you 
>>>> have some experience on using the intensities as input for the protein 
>>>> ratio/abundance calculation? I tried to see if I could build it it up 
>>>> using 
>>>> the intensities but the peptides are annotated different in the Pepxml, 
>>>> than in the Protxml. All modifications are annotated either with the more 
>>>> precise mass shift or rounded. e.g CAM is reported as C[160.03] for the 
>>>> peptides in the Pepxml whereas as C[160] for in Protxml.
>>>>
>>>> Another question that I have related to xpress is if you have any 
>>>> experience on better settings for data analyzed on hi-res MS, ie. Q 
>>>> Exactive. Fixed elution peaks, number of chromatograms points, or number 
>>>> of 
>>>> 13C isotopic peaks. 
>>>>
>>>> Any thoughts on this?
>>>>
>>>> Best,
>>>>
>>>> Alejandro 
>>>>
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>>>
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