I've uploaded the pepXML files, the parameters I used, and the database 
here. 
<https://drive.google.com/drive/folders/1gJoi9fqsmIYg_0tl_2Ur-n04MJyuotyc?usp=sharing>
Please let me know if I should be uploading anything else! Thank you!

On Saturday, October 17, 2020 at 12:04:21 AM UTC-4 Emily Kawaler wrote:

> Thank you! I'm working on getting it transferred to Drive, so it might 
> take a little while, but I'll be in touch!
>
> On Tuesday, October 13, 2020 at 3:08:44 PM UTC-4 David Shteynberg wrote:
>
>> Hello Emily,
>>
>> If you are able to share the dataset including the pepXML file and the 
>> database I can try to replicate the issue here and try to troubleshoot the 
>> sticking point.
>>
>> Thanks,
>> -David
>>
>> On Tue, Oct 13, 2020 at 11:15 AM Emily Kawaler <[email protected]> wrote:
>>
>>> Hello, and thank you for your response! It doesn't look like the process 
>>> is using too much memory (I've allocated 300 GB and it's maxing out around 
>>> 10), and I've kicked up the minprob parameter - it's still getting stuck, 
>>> unfortunately. 
>>> Emily
>>>
>>> On Friday, October 9, 2020 at 2:24:37 PM UTC-4 Luis wrote:
>>>
>>>> Hello Emily,
>>>>
>>>> This is not a problem that we have seen much of.  Do you know which 
>>>> version of ProteinProphet / TPP you are using?
>>>>
>>>> One potential issue is the large number of proteins (and peptides) that 
>>>> it is trying to process -- can you either monitor the memory usage of the 
>>>> machine when you run this dataset, and/or try on one with more memory?
>>>>
>>>> Hope this helps,
>>>> --Luis
>>>>
>>>>
>>>> On Tue, Oct 6, 2020 at 6:32 PM Emily Kawaler <[email protected]> wrote:
>>>>
>>>>> Hello! I've been running ProteinProphet as part of the Philosopher 
>>>>> pipeline for a while now with no problems. However, one of my datasets 
>>>>> seems to be getting stuck in the middle of this function. It doesn't 
>>>>> throw 
>>>>> an error or anything - just stops advancing (the last 
>>>>> line of the output is "Computing degenerate peptides for 69919 
>>>>> proteins: 0%...10%...20%...30%...40%...50%"). Has anyone run into this 
>>>>> problem before?
>>>>>
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