I have also been encountering this issue and would love to hear a solution. 
The search still reads as "Running" but simply stops searching any more 
mzML files. Depending on the size of my  files, the search times out at 
different points, but will almost never search more than 8 files at a time. 

Happy to provide an example dataset + parameters + FASTA file if anyone 
wants to try and replicate the timeout.

-Will

On Wednesday, November 10, 2021 at 1:32:09 AM UTC-5 [email protected] 
wrote:

> Hi everyone,
>
> I've been using TPP for a little while now for the analysis of my data. I 
> have been using Comet to perform database searching on a large number of 
> mzml files and have noticed that the analysis will usually time out after 
> about 6 hours. In this case, I will remove the mzml files that have been 
> successfully processed and then re-run comet. Is this job time-out an 
> inherent part of TPP, or is it a setting that can be changed? If the 
> latter, are there any risks in running the analysis for over 6 hours?
>
> Thanks in advance for any advice
> Steven
>

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